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  • 1
    Electronic Resource
    Electronic Resource
    Increased carotid intima–media thickness in patients with inflammatory bowel disease (2005)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 22 (2005), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Patients with inflammatory bowel disease have an increased risk of thrombotic complications; moreover, mesenteric microvascular thrombosis has been hypothesized as a contributing factor in the pathogenesis of inflammatory bowel disease.Aim : To assess the extent of subclinical atherosclerosis in inflammatory bowel disease by measuring the intima–media thickness of the common carotid artery.Methods : Fifty-two patients were enrolled in the study. Patients aged 〉45 years, with a history of cardiovascular disease and known risk factors for atherosclerosis were excluded from the study. Twenty healthy subjects were studied as controls. Carotid ultrasonography was performed in all patients and controls. intima–media thickness was measured proximal to the carotid bifurcation over both right and left common carotid arteries. The clinical characteristics and the laboratory parameters relevant to disease activity were recorded for all inflammatory bowel disease patients. In particular, plasma homocysteine, a well-known risk factor for thrombosis, was assessed.Results : Common carotid artery intima–media thickness was significantly higher in inflammatory bowel disease patients (0.63 ± 0.15 mm) compared with controls (0.53 ± 0.08 mm). Multiple regression analysis revealed a significant association of carotid intima–media thickness with homocysteine levels and age.Conclusions : Inflammatory bowel disease patients have an increased risk of early atherosclerosis than healthy controls as showed by greater values of carotid intima–media thickness. Homocysteine levels and age resulted independently associated with the increased arterial wall thickness.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2005.02657.x
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  • 2
    Electronic Resource
    Electronic Resource
    Immune parameters in a populatio of institutionalized elderly subjects: influence of depressive disorders and endocrinological correlations
    Amsterdam : Elsevier
    Mechanisms of Ageing and Development 60 (1991), S. 1-12 
    Details
    ISSN: 0047-6374
    Keywords: Aging ; Cutaneous delayed hypersensitivity ; Lymphocyte subsets ; Psychoneuroendocrinoimmunology
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0047-6374(91)90104-8
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  • 3
    Electronic Resource
    Electronic Resource
    Carbon-14 net incorporation does not accurately estimate the weight-specific growth rate of the polychaete Capitella capitata (1984)
    Springer
    Marine biology 79 (1984), S. 101-107 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Tracer techniques to measure carbon-14 incorporation from labeled food can seriously overestimate the growth of an organism. The degree of overestimation can change with varying food supply and correlates with changes in the tracer activity in lipid and protein pools of the organism. These changes may be associated with differential metabolic partitioning of newly assimilated food.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00404991
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  • 4
    Electronic Resource
    Electronic Resource
    Impairment of lymphocyte activities in depressed aged subjects
    Amsterdam : Elsevier
    Mechanisms of Ageing and Development 60 (1991), S. 13-24 
    Details
    ISSN: 0047-6374
    Keywords: Aging ; Interferon ; Interleukins ; Lymphocyte blastogenesis ; NK activity ; Psychoneuroendocrinoimmunology
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0047-6374(91)90105-9
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  • 5
    Electronic Resource
    Electronic Resource
    Photosynthesis of two poplar clones contrasting in O3 sensitivity (1998)
    Springer
    Trees 12 (1998), S. 196-200 
    Details
    ISSN: 0931-1890
    Keywords: Key words Gas exchange ; Chlorophyll fluorescence ; Membrane leakage ; Populus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition
    Notes: Abstract  Two clones of poplar known for their phenomenological difference in response to ozone were fumigated with 150 nl l–1 of ozone for 5 h. In both clones the treatment significantly reduced the light-saturated rate of CO2 uptake of recently mature leaves and this was accompanied by a decrease in stomatal conductance. Intercellular CO2 concentration of the resistant clone increased following the fumigation. After 20 h of recovery, photosynthesis recovered completely only in the resistant clone. Electrolyte leakage of leaf disks increased in both clones to indicate damage to membranes; after the recovery time this parameter only reached values of the control in the resistant clone. The photochemical efficiency of PSII slightly decreased in the resistant clone. In the other clone, the treatment caused a decline of all chlorophyll fluorescence parameters and only some of them returned to normal values after the recovery time. The physiological response appears to be different in the two clones. In the resistant one, the most probable mechanism involved in the photosynthetic reduction was a regulatory reduction in CO2 fixation. Also data obtained by the solute leakage indicate that in the resistant clone repair mechanisms play a role. The reduction of photosynthesis observed in the sensitive clone is related both to strong stomatal closure and to an impairment in fluorescence parameters. These alterations can indicate a general disruption at the membrane level as confirmed by the solute leakage data.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00009710
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  • 6
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    Unknown
    Ripafratta (Pisa). 3 (1989)
    Firenze : Periodicals Archive Online (PAO)
    Archeologia medievale. 16 (1989) 425 
    Details
    ISSN: 0390-0592
    Topics: Archaeology , History , Art History
    Notes: "NOTIZIE, SCAVI E LAVORI SUL CAMPO"
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:e315-1989-016-00-000023
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  • 7
    Electronic Resource
    Electronic Resource
    Long-term nervous system damage from radiation of the spinal cord: An electrophysiological study (1991)
    Springer
    Journal of neurology 238 (1991), S. 9-15 
    Details
    ISSN: 1432-1459
    Keywords: Radiation damage ; Spinal cord ; Magnetic resonance imaging ; Somatosensory evoked potentials ; Motor evoked potentials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A group of 13 patients suffering from Hodgkin's disease who had undergone chemotherapy and radiotherapy (above and below the diaphragm) approximately 10 years earlier was studied. The total chemotherapeutic dose was similar for all patients; the radiotherapy dose, however, was standard for 7 patients, while the other 6 received much higher dosages over limited regions of the spinal cord. Although most of these patients appeared normal both clinically and on magnetic resonance imaging, a neurophysiological study was performed to determine whether there was any involvement of the central or peripheral nervous system. Motor conduction velocity and sensory conduction velocity were measured in the lower limbs as well as spinal- and scalprecorded somatosensory evoked potentials (SEPs) in response to stimulation of the posterior tibial and sural nerves at the ankle. In addition, motor evoked potentials were recorded from the upper and lower limbs during cortical stimulation. All neurophysiological data were normal in patients who had received a standard radiation dose, while most of those who had been exposed to higher doses showed altered cortical SEPs and a slowing of central conduction time (D10-P1). Thus even though they were asymptomatic, these patients appeared to have sustained CNS damage, mainly at the level of the spinal cord.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319702
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  • 8
    Electronic Resource
    Electronic Resource
    Myasthenia gravis, thymectomy, and antiacetylcholine receptor antibody (1980)
    Springer
    Journal of neurology 224 (1980), S. 9-15 
    Details
    ISSN: 1432-1459
    Keywords: Myasthenia gravis ; Acetylcholine receptor ; Antiacetylcholine receptor antibody ; Thymus ; Thymectomy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Antikörper gegen Acetylcholin-Rezeptoren wurden quantitativ im Serum von 63 Patienten mit Myasthenia Gravis und von 20 gesunden Kontrollpersonen bestimmt. Der Titer war bei 92% der Myasthenie Gravis-Patienten signifikant erhöht, jedoch bei keinem der Kontrollfälle. Es wurde keine Korrelation zwischen dem Titer einerseits und den pathologischanatomischen Besonderheiten beziehungsweise dem klinischen Schweregrad der Erkrankung andererseits festgestellt. Der Titer nahm nach Thymektomie ziemlich geradlinig ab, parallel zur klinischen Besserung der Myasthenie. Es wird die Rolle der Antikörper bei der Pathogenese der Erkrankung diskutiert.
    Notes: Summary The antiacetylcholine receptor antibody was titered in the serum of 63 patients with myasthenia gravis (MG) and 20 control healthy subjects. The titer was significantly high in 92% of MG patients in contrast with none of the controls and no correlation was found with the thymus pathology and the severity of the disease. The titer decreased after thymectomy almost steadily with the improvement of the myasthenic signs. The role of the antibody in the pathogenesis of the disease is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00313202
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  • 9
    Electronic Resource
    Electronic Resource
    Pulmonary alveolar microlithiasis: Review of Italian reports (1997)
    Springer
    European journal of epidemiology 13 (1997), S. 587-590 
    Details
    ISSN: 1573-7284
    Keywords: Calculi ; Case reports ; Diagnosis ; Epidemiology ; Lung diseases ; Review article
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Pulmonary alveolar microlithiasis (PAM) is a rare disease of unknown etiology, characterized by the presence of calcific concretions in the alveolar spaces. A familial occurrence is frequently found so that an inherited trait is thought to be involved. The chest X-ray is characterized by a ‘sandstorm’ picture while the clinical state undergoes to a slow and progressive impairment resulting in respiratory failure at the end stage. We have reviewed the Italian literature of the past 50 years detecting 48 case-reports of PAM (19 males and 29 females). Only 20 out of them were documented in international journals. A familial occurence of 43.7% was found and 18 patients were under age fifteen. There was a prevalence in the female sex (60.4%) and in the second decade of life. Chest X-ray was the most important tool to diagnose PAM revealing the characteristic picture in all patient. Bronchoalveolar lavage (BAL) and open lung biopsy respectively show the characteristic calcospherites in the recovered fluid (BALF) and in the alveolar spaces. About 300 cases of PAM are reported in the international literature. We believe these data are probably underestimated because many case-reports are not published in international literature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1007399812798
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  • 10
    Electronic Resource
    Electronic Resource
    Imaging axonal damage in multiple sclerosis by means of MR spectroscopy (2000)
    Springer
    Neurological sciences 21 (2000), S. S883 
    Details
    ISSN: 1590-3478
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Axonal damage in multiple sclerosis has become an important issue. This has been emphasized by recent in vivo proton magnetic resonance (MR) spectroscopy and in vitro pathology studies that have found axonal damage in both lesions and the surrounding normal-appearing white matter. In particular, proton MR spectroscopy, by monitoring levels of N-acetylaspartate (a putative marker of axonal integrity), has been particularly illuminating, as the extent of axonal injury associated with white matter inflammation and demyelination had not been well appreciated from classical pathology studies. Recent MR data demonstrate that cerebral axonal damage begins and contributes to disability from the earliest stages of the disease. This implies that the apparently primary role of axonal damage and loss in the pathogenesis of the disease should be given due importance, and argues for the early treatment of multiple sclerosis with agents directed not only against inflammation, but also towards axonal protection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100720070031
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