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  • 1
    Electronic Resource
    Electronic Resource
    PSYCHOSOCIAL STRESS INDUCES TUBULOINTERSTITIAL NEPHRITIS UNRELATED TO HYPERTENSION IN CBA MICE (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 8 (1981), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Groups of mice interacting socially in complex population cages become hypertensive. Some also develop fatal chronic tubulointerstitial nephritis.2. Long-term administration of the cardioselective β-blocker metoprolol controls stress-induced elevation of plasma renin and adrenal tyrosine hydroxylase. It also normalizes blood pressure. Despite the effectiveness of this sympathetic blockade, the incidence of nephritis was not diminished.3. The fact that stress-induced increases of adrenal weight and plasma cortico-sterone persist during metoprolol treatment points to the independence of the pituitary-adrenal cortical system and its possible role in the aetiology of renal disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1981.tb00754.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    HISTORICAL PERSPECTIVE OF CARDIORENAL INTEGRATION (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 22 (1995), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. Early research on blood volume as an independent parameter affecting kidney function took the approach that the sensors must be located in the most compliant, that is the reservoir portion, of the cardiovascular system. This encompasses the great veins and the cardiac atria.2. Small changes in volume were shown not to affect the compliance of this reservoir and messages from the atrial receptor network were shown to travel in the vagus nerve and to control urine volume by antidiuretic hormone.3. Although greatly affected by the water immersion stimulus, sodium excretion was not as dependent on vagus integrity. The ensuing search for the natriuretic arm of the blood volume mechanism persisted for the next 20 years.4. Finally, one aspect of the elusive natriuretic factor was found exactly where theory had suggested, namely the most distensible part of the system, in specialized granules in the cardiac atria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1995.tb01917.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Beitrag zur Homöostase des extraarteriellen Kreislaufs (1956)
    Springer
    Journal of molecular medicine 34 (1956), S. 356-366 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01469349
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Changes in Enzymes involved in the Biosynthesis and Metabolism of Noradrenaline and Adrenaline after Psychosocial Stimulation (1970)
    [s.l.] : Nature Publishing Group
    Nature 225 (1970), S. 1059-1060 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Control groups consisted of mice which had normal nursing and sibling contact until three to four weeks old and were then weaned. The sexes were separated and maintained six to eight siblings per standard cage 27 14 13 cm until eight months of age. Stimulus-deprived mice were removed from mother ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/2251059a0
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  • 5
    Electronic Resource
    Electronic Resource
    Elevated serum levels of tumor marker CA19-9 in acute cholangitis (1988)
    Springer
    Digestive diseases and sciences 33 (1988), S. 1223-1225 
    Details
    ISSN: 1573-2568
    Keywords: CA19-9 ; cholangitis ; biliary tract disease ; tumor marker
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The purpose of the present study was to examine the relationship between the “tumor marker,” CA19-9, and benign biliary tract disease. We measured serum and bile CA19-9 in 40 patients with (1) symptomatic cholelithiasis (N=14), (2) common bile duct obstruction without cholangitis (N=8), (3) acute cholangitis secondary to gallstone disease (N=7), and (4) acute cholecystitis (N=11). All seven patients with acute cholangitis had marked elevations of serum CA19-9 (range 190-32,000 units/ml; 75 units/ml cutoff), whereas none of the patients in the other groups had elevated levels despite similar degrees of cholestasis and similarly high levels of CA19-9 in gallbladder and common duct bile (range 7.3×104−2.3×109 units/ml). Of the three patients with cholangitis in whom CA19-9 levels were followed serially, all had rapid return of levels to normal after successful treatment. We conclude that the “tumor marker” CA19-9 is markedly elevated in the serum of patients with acute cholangitis but not in patients with other forms of benign biliary tract disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01536670
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    Paper (German National Licenses)
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