ISSN:
1432-0428
Keywords:
Thyroxine
;
triiodothyronine
;
reverse T3
;
glucose utilization
;
glucose metabolic clearance rate
;
ketones
;
oxygen consumption
;
cortisol
;
insulin
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Thyroid hormones have been measured in normal subjects and insulin-requiring diabetic patients before and after treatment. Plasma thyroxine (T4) and 3, 3′, 5-triiodothyronine (T3) concentrations were both low in diabetics, with T3 frequently in the hypothyroid range, while 3, 3′, 5′-triiodothyronine (rT3) concentrations were elevated. All three returned to normal following treatment. T3 concentration was directly related to glucose utilization and metabolic clearance rate; and inversely related to plasma ketone body concentration. Thyroid hormone abnormalities in diabetes may reflect the degree of insulin-secreting capacity.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01219324
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