ISSN:
1432-1041
Keywords:
Celiprolol
;
Maternofetal transfer
;
enantioselectivity
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
,
Medicine
Notes:
Summary The maternofetal transfer of the β1-selective adrenergic antagonist celiprolol has been studied in four hypertensive pregnant women. Fetal plasma concentrations were about 25–50% of the levels found on the maternal side. There was no significant difference between the plasma concentrations of the two enantiomers in the child. Therefore, in further investigations only the racemate needs to be determined.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00316477
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