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  • 1
    Electronic Resource
    Electronic Resource
    Cytoskeletal characteristics of myofibroblasts in benign neoplastic and reactive fibroblastic lesions (1990)
    Springer
    Virchows Archiv 416 (1990), S. 375-382 
    Details
    ISSN: 1432-2307
    Keywords: Myofibroblast ; Cytoskeleton ; Desmoid tumour ; Desmin ; Immunohistochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The characteristics of the cytoskeleton of myofibroblasts were examined immunohistochemically in 10 extra-abdominal desmoid tumours, 3 palmar and 2 plantar fibromatoses and 5 nodular fasciites; in the cultured cells of one desmoid tumour, and also ultrastructurally in 3 desmoid tumours. Polyclonal anti-desmin antibody reacted with the cells in 7 extra-abdominal desmoid tumours, 1 palmar fibromatosis, 1 plantar fibromatosis and 3 nodular fasciites. Monoclonal antidesmin antibody reacted with cells in only 2 desmoid tumours. Desmin-positive spindle cells were scattered throughout these lesions. There were no marked ultrastructural differences between desmin-positive and desmin-negative desmoids. All specimens except one specimen of nodular fasciitis showed immunoreactivity for alpha-smooth muscle actin and vimentin. Muscle actin-positive cells were observed in all specimens. Cultured cells gave positive reactions with polyclonal desmin antibody as well as to vimentin antibodies and two preparations of actin antibodies, whereas the original tumour did not react with desmin antibody. The present studies suggested that the cytoskeleton of some myofibroblasts in both neoplastic and reactive lesions resembles that of smooth muscle cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01605141
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Cat scratch disease (1988)
    Springer
    Virchows Archiv 412 (1988), S. 563-572 
    Details
    ISSN: 1432-2307
    Keywords: Cat scratch disease ; Epidemiology ; Ultrastructure ; Bacterial morphology ; Warthin-Starry stain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aetiological agent of cat scratch disease (CSD) has been unknown for more than 30 years. Recently, a micro-organism clearly shown with Warthin-Starry silver (W-S) stain was found and thought to be a possible cause of the disease. In this study, 32 cases of regional lymphadenopathy histologically compatible with CSD and 20 contrasting cases of lymphadenopathy were examined retrospectively with W-S stain. W-S positive pleomorphic organisms were clearly demonstrated in 20 of the 32 suspected cases of CSD, but in none of the other cases. The onset of disease in these 20 cases with W-S positive organisms occurred between July and January. This seasonal variation in the onset of disease was highly significant (P〈0.005) and was not due to a single epidemic. Moreover, some characteristic morphological features of the organism were found by electron microscopic observations. Ultrastructurally, the organism was a bacterium showing a chain-like arrangement, septal formation, branching and clubbed ends.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00844292
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Die Infarkte der A. cerebri posterior: Pathogenese und topographische Beziehungen zur Sehrinde (1966)
    Springer
    European archives of psychiatry and clinical neuroscience 208 (1966), S. 263-284 
    Details
    ISSN: 1433-8491
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung 35 Infarkte im Versorgungsgebiet der A. cerebri posterior wurden morphologisch untersucht und mit den klinischen Befunden korreliert. 1. Posterior-Infarkte machen unter den Hirninfarkten insgesamt etwa 10% aus und befallen das vorgerückte Lebensalter mit einem Gipfel um das 70.–75. Lebensjahr. Sie sind in fast 80% der Fälle mit weiteren Läsionen vasculärer Genese, insbesondere mit Media- und Kleinhirninfarkten, assoziiert. 2. Die Mehrzahl der Posterior-Infarkte nimmt die mittleren Bezirke des Versorgungsgebietes ein, so daß die rostralen (Mittelhirn, Thalamus) sowie die am weitesten distal gelegenen Bezirke häufig von der Infarzierung ausgespart bleiben. Der die zentralen Gesichtsfeldanteile repräsentierende Occipitalpol war in 20% der Fälle vollständig, in weiteren 11% partiell betroffen. 3. Die Infarkte tendieren zu einer mehr basalen Ausdehnung mit bevorzugter Lokalisation um den Sulcus collateralis. Die Unterlippe der Fissura calcarina ist deshalb viel häufiger betroffen (in 22% der Fälle isoliert) als die Oberlippe. Unter- und Oberlippe der Calcarina waren in 47% infarziert. Völlige Aussparung der Area striata zeigten 28% der Fälle. Klinisch müssen also homonyme Hemianopsien sowie partielle obere Gesichtsfelddefekte, jeweils unter Aussparung der Macula, für die Posterior-Infarkte als charakteristisch angesehen werden. 4. Pathogenetisch ließen sich der Totalinfarkt und der stumpfnahe Infarkt bei proximalem Verschluß sowie der auf hämodynamischen Faktoren basierende Infarkt im Zentrum des Versorgungsgebietes unterscheiden. 5. Bei unzureichender Verbindung der hinteren Hirnarterie mit dem Basilarissystem können Posterior-Infarkte auch durch Stenosen und Verschlüsse im Verlaufe der A. carotis hervorgerufen werden, in seltenen Fällen sogar als deren einziges Symptom hervortreten.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341689
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  • 4
    Electronic Resource
    Electronic Resource
    Central intravascular papillary endothelial hyperplasia of the mandible (1984)
    Springer
    Virchows Archiv 403 (1984), S. 453-459 
    Details
    ISSN: 1432-2307
    Keywords: Intravascular endothelial hyperplasia ; Mandible
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Light and electron microscopic findings in papillary endothelial hyperplasia of the mandible in a 49-year-old female are reported. The endothelial cell-lined papillary projection into a cystic lumen was examined by light microscopy and characteristic features of the endothelial cells were found by electron microscopy. Factor VIII-related antigen was demonstrated in the endothelial cells by the immunoperoxidase technique.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00737293
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    A rare case of fibroadenoma in a tubular adenoma of the breast (1992)
    Springer
    Surgery today 22 (1992), S. 163-165 
    Details
    ISSN: 1436-2813
    Keywords: tubular adenoma ; fibroadenoma ; breast adenoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report herein a case of a 31 year old housewife who underwent an excisional biopsy for a well-circumscribed lump in her breast. The lump contained 2 histological patterns, namely, fibroadenoma and tubular adenoma. These patterns had no transitional zone, were distinct and changed abruptly. This case was histologically diagnosed as “a fibroadenoma in tubular adenoma of the breast, benign”, with no other such case ever having been reported in Japan. The histological findings of this case, convinced us that tubular adenoma is closely related to fibroadenoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00311343
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    Paper (German National Licenses)
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