ISSN:
1399-0047
Source:
Crystallography Journals Online : IUCR Backfile Archive 1948-2001
Topics:
Chemistry and Pharmacology
,
Geosciences
,
Physics
Notes:
A recombinant human uroporphyrinogen decarboxylase (E.C. 4.1.1.37, UROD) has been expressed in Escherichia coli and purified to homogeneity. Crystals grew by the hanging-drop vapor-diffusion technique from a starting solution containing 1.5 mg ml−1 protein. The crystals belong to the trigonal space group P3121 or its enantiomer P3221 and diffract to 3 Å resolution. The unit-cell parameters are a = b = 103.4, c = 75.7 Å and γ = 120°. The asymmetric unit contains one molecule. Preliminary structural predictions suggest for the protein a TIM-barrel type tertiary structure.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1107/S090744499701250X
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