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  • 1
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 194 (1962), S. 98-99 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cereariae of S. japonicum used were newly shed from the snail, Oncomelania nosophora, obtained from Japan. The cercariae were irradiated in dechlorinated tap-water suspensions 10 mm. deep and 17 mm. in diameter; thus the volume was about 2-25 ml. The vessels containing the liquid were of glass ...
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 206 (1965), S. 1338-1340 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] IN recent years, immunization against schistosomiasis has become a challenging research problem. In this laboratory we reported that the inoculation of rhesus monkeys, Macaco, mulatta, with cercariae of the Formosan (F) non-human strain of Schistosoma japonicum gives a high degree of protection ...
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract Skin sections of rhesus monkeys immunized with X-irradiatedSchistosoma japonicum cercariae were stained by an unlabeled antibody enzyme method for the detection of IgG, IgM, IgA, IgE, and C3. While all of them could be found in the skin lesions, their distribution patterns varied with time and reactions. In whealing reaginic reactions, IgE appeared prominent, having an affinity to the mast cells. In Arthus-like reactions, IgG was predominant. IgG complexes were found on the schistosomula, on the walls of blood vessels, and in granulocytes near the schistosomula. In the late stage of Arthus-like reactions and in delayed hypersensitive reactions, IgA was predominant in granulocytes, mononuclear cells, and macrophages. Characteristics of each immunoglobulin pattern seemed to reflect its function in the effector mechanism. It may be speculated that these immunoglobulins and C3, together with effector cells, synergistically and sequentially destroy schistosomula in the skin.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The lung recovery assay for schistosomula has recently been used as a rapid method for measuring the state of immunity of a challenged animal. Its merit rests on the fact that the peak day of schistosomular recovery in the lungs of both normal and immune hosts falls on the same day and the degree of immunity can be measured by the percent of schistosomular recovery on this particular day. An evaluation of this method for mice immunized with highly X-irradiated cercariae ofSchistosoma mansoni was made. The results indicate that in the immunized mice the peak day for the schistosomular recovery was delayed and the number of schistosomula recovered on the peak day was decreased. The delay of the peak day was increased by the degree of host immunity, so its identification for a host of an unknown immunologic status was not a simple matter. In addition, this method measured only the immune effect which took place in the skin and on prepeak days in the lungs. It was not as competent as the conventional liver perfusion method which measures the total result of the immune effect of the skin, lungs, and liver. Our conclusion is that for measuring the immunizing effect of irradiated cercariae, the lung recovery method is not suitable for the determination of the state of immunity induced.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1955
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract To find direct evidence for the sites of death of newly transformed schistosomula ofSchistosoma mansoni in the skin of challenged immunized hosts, a histopathological study of the skin of chronically infected mice and of highly X-irradiated cercaria-immunized mice was made at different post-challenge times. Attrition of infecting organisms in naive mice was used as a control. In general, three main kinds of schistosomular attrition were observed: (1) in the granulocytic exudates in the epidermis, (2) in the granulocytic aggregates in the subcutaneous tissue, and (3) in the granuloma-like foci in the subcutaneous tissue. Schistosomula killed by the epidermal granulocytic exudates and by the subcutaneous granuloma-like foci occurred in all three groups of mice, but the schistosomula killed by the subcutaneous granulocytic aggregates were found only in the highly X-irradiated cercaria-immunized animals. Schistosomula killed by the epidermal granulocytic exudates were encountered occasionally in the challenged naive mice but more frequently in both the challenged chronically infected mice and the challenged highly X-irradiated cercaria-immunized mice. The number of subcutaneous granuloma-like foci was greater in the challenged mice immunized with highly X-irradiated cercariae than in the challenged naive mice or the challenged chronically infected mice. Another differentiating character among the three groups of mice was that in the highly X-irradiated cercaria-immunized group, the subcutaneous granuloma-like foci appeared on day 3 after the challenge, but on day 5 in the naive and chronically infected groups. The results clearly indicate that skin is an important site for the attrition of the challenged cercariae in the highly X-irradiated cercaria-immunized mice, and that immunity in the chronically infected and X-irradiated cercaria-immunized mice occurs by different mechanisms.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of the American Chemical Society 108 (1986), S. 3838-3839 
    ISSN: 1520-5126
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0495
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract Lake Zürich occupies a glacially overdeepened perialpine trough in the northern Middlelands of Switzerland. A total of 154.4 m of Quaternary sediments and 47.3 m of Tertiary Molasse bedrock has been cored from the deepest part of the lake, some 10 km south of the city of Zürich. Some 16.8 m of gravels and sands directly overlying the bedrock include basal till and probably earliest subglacial fluvial and lacustrine deposits. These are overlain by 98.6 m of fine-grained, glacial-aged sediments comprising completely deformed proglacial and/or subglacial lacustrine muds, separated by four basal mud tills. The lack of interglacial sediments, fossils, and other datable material, and the presence of severe sediment deformation and unknown amounts of erosion prevent the establishment of an exact chronostratigraphy for sediments older than the upper mud till. Above it some 8.6 m of lacustrine muds were deposited, folded, faulted, and tilted during the final opening of the lake at about 17,500–17,000 years ago. Superimposed are 30.4 m of final Würm and post-glacial sediments comprising (from oldest): cyclic proglacial mud, thick-bedded and laminated mud, a complex transition zone, laminated carbonate, laminated marl, and diatom-calcite varves. These sediments reflect changing catchment and lacustrine conditions including: glacial proximity, catchment stability, lake inflow characteristics, thermal structure, chemistry, and bed stability. Average sedimentation rates ranged from 11 cm yr−1 immediately after glacier withdrawal, to as low as 0.4 mm yr−1 as the environment stabilized. The lack of coarse outwash deposits separating the fine-grained glaciolacustrine sediments from a corresponding underlying basal till suggests that deglaciation of the deep northern basin of Lake Zürich was by stagnation-zone retreat rather than by retreat of an active ice-front.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Mathematische Annalen 206 (1973), S. 177-186 
    ISSN: 1432-1807
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 505-507 (Jan. 2006), p. 889-894 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The knowledge obtained from the experience of monitoring manufacturing process iscritical to guarantee good products produced at the end of manufacturing line. Recently, many methods have been developed for the described purpose above. In this paper, a new knowledge discovery model based on soft computing is proposed. The proposed model contains a new algorithm Modified Correlation-based Feature Selection (MCFS), a new algorithm Modified Minimum Entropy Principle Algorithm (MMEPA), and Variable Precision Rough Set Model (VP-model). Afterconducting a real case of monitoring the process of manufacturing industrial conveyor belt, some advantages of the proposed model are that (1) MCFS can quickly identifying and screening irrelevant, redundant, and noisy features for data reduction; (2) MMEPA can objectively construct membership functions of fuzzy sets for fuzzifing the reduced dataset; (3) VP-model can extract causal relationship rules for controlling product quality; (4) Extracted rules by the proposed knowledge discovery model are easily understood and interpretable
    Type of Medium: Electronic Resource
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