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  • 1
    Electronic Resource
    Electronic Resource
    Microvascular endothelial abnormality in skeletal muscle from a patient with gastric cancer without dermatomyositis (2000)
    Springer
    Acta neuropathologica 100 (2000), S. 718-722 
    Details
    ISSN: 1432-0533
    Keywords: Key words Thrombomodulin ; Paraneoplastic phenomenon ; Endothelial cell ; Myalgia ; Thrombophlebitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We found a microvascular endothelial abnormality in a biopsy specimen from the gastrocnemius muscle of a patient with gastric cancer, who had severe myalgia and angialgia in the calf region with the symptoms of thrombophlebitis. There were no definite findings of inflammatory myopathy in histochemical and immunohistochemical studies. Electron microscopic examination revealed the accumulation of abnormal mitochondria in the subsarcolemmal area, and a fair number of degenerating capillaries. Immunohistochemical analysis of procoagulant or anticoagulant factors revealed marked reduction of thrombomodulin (TM) expression on small vessels and capillaries. Although a reduction of TM on small vessels has been observed around perifascicular atrophic fibers in patients with dermatomyositis, histochemical findings of the present patient showed no perifascicular atrophy or severely degenerating fibers. These pathological findings in the patient may be related to a malignant neoplasm and may be one of the causes of disseminated intravascular coagulation (DIC), which is the main complication of malignant neoplasms. Further studies are necessary to determine whether the reduction of TM on the small vessels and capillaries in skeletal muscle is a predictor of some severe condition such as DIC or a rare pathological finding in some special condition such as scirrhous carcinoma with thrombophlebitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004010000243
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  • 2
    Electronic Resource
    Electronic Resource
    Cutting Force Experiment and Simulation by Hard Turning GCr15 Bearing Steel with High Speed Considering Cutting Edge Preparation (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 532-533 (Dec. 2006), p. 845-848 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this study, hard turning GCr15 bearing steel with high cutting speed is experimentalinvestigated the influence of the CB7015WH insert with chamfer edge and Safe-Lock and theCB7015 insert with a combination of hone radius and a chamfer edge on cutting forces and surfaceroughness of machined surface. Experimental results show that the cutting forces of the chamferedge and Safe-Lock is smaller than that of the combination of hone radius and a chamfer edge.Moreover, surface roughness of machined surface with the CB7015WH insert is better.A coupled thermo-mechanical 2D finite element model with general finite element analysissoftware Deform 2D.8.1 is developed for the influence of two kinds of inserts on cutting forces andeffective stress. The simulation results are compared with experimental data and found to be ingood agreement
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/14/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.532-533.845.pdf
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of Different Edge Preparation on High Speed Turning Hardened Steel Process (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 532-533 (Dec. 2006), p. 412-415 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Through combining turning experiments and FE simulations, this paper studied theeffects of force, temperature and residual stress of machined surface on high speed hard turningGCr15 bearing steel hardened to HRC60-62 with three kinds of ordinary edge preparation(sharp-edge, hone and chamfer). The experiment and simulation results indicated that thediathermanous proportion of chamfered edge preparation to tool and machined surface is less, andthis distribution of cutting temperatures is useful for tool life and machined surface quality. Thesimulation results showed that cutting force had a descending tendency with increasing of cuttingspeed, which is in accordance with the change rules of machining general rigidity material, and itproved that FE simulations have good precision. The simulation results of residual stress ofmachined surface showed that residual tensile stress existed in machined surface using both honedand chamfered tools, and a highest compressive stress (about -200MPa) existed among 150-200μmof the depth into the workpiece surface. The difference was that the depth of superficial hardenlayer with honed tools is larger than that with chamfered tools
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/14/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.532-533.412.pdf
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  • 4
    Electronic Resource
    Electronic Resource
    Effect of Air Cooling on the Process of High Speed Hard Cutting GCr15 (2006)
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 532-533 (Dec. 2006), p. 369-372 
    Details
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Air cooling is a near dry machining method, which cools cutting area and evacuates chipusing low temperature wind instead of cutting liquid. It can decrease tool wear, improve tool life,reduce cost and produce no chemical pollution. In this paper, air cooling system is established, inwhich vortex tube is used for cooling. Air cooling test was carried on, in which high hardness bearsteel GCr15 is machined by PCBN tool. Experiment results indicated that cold air from vortex tubehas a significant effect on cutting force, cutting temperature and chip formation process. Cuttingforce and cutting temperature were simulated using Marc. Change rules that analysis resultsindicated are in accordance with experiment results. This paper’s conclusions have a great referencevalue for the practical application of air cooling technology
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/02/14/transtech_doi~10.4028%252Fwww.scientific.net%252FMSF.532-533.369.pdf
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  • 5
    Electronic Resource
    Electronic Resource
    Demonstration and Characterization of the Iron Regulatory Protein in Human Brain (1996)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 67 (1996), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Iron regulatory proteins (IRPs) are cytoplasmic RNA binding proteins that regulate expression of ferritin, erythroid 5-aminolevulinic acid synthase, and transferrin receptor through interaction with conserved RNA stem-loop structures called iron-responsive elements (IREs). Two IRPs (IRP1 and IRP2) have been reported. In the present study we provide evidence for and initial characterization of the IRPs in human brain. Two RNA-protein complexes were obtained by RNA band shift assay on cytoplasmic extracts from human brain. Competition studies indicate that the formations of the RNA-protein complexes are specific to the IRE structure. UV cross-linking of brain cytoplasmic extracts with ferritin IRE RNA transcripts revealed a single RNA-protein complex with a molecular mass of 110 kDa. A single band at 100 kDa was obtained with IRP1 antiserum on western blot analysis of brain cytoplasmic extracts, and a supershift in the RNA-protein complexes was observed with an IRP1 antiserum. Two cDNA clones were isolated from a human brain cDNA library with IRP1 cDNA probes, and both of these cDNA probes recognized a single mRNA species (4.0 kb) from human astrocytoma cells. Purified human brain IRP protein has a molecular mass of ∼100 kDa and is capable of forming two RNA-protein complexes with ferritin IRE RNA and reacts strongly with IRP1 antiserum. These data indicate that IRP1 is predominant in the adult human brain and, in this tissue, is capable of forming a double IRE/IRP complex. This latter observation suggests the brain IRP undergoes posttranslational modification, the result of which may influence the stability of the IRE/IRP complex.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1996.67020838.x
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  • 6
    Electronic Resource
    Electronic Resource
    A stomatin-domain protein essential for touch sensation in the mouse (2007)
    [s.l.] : Nature Publishing Group
    Nature 445 (2007), S. 206-209 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Touch and mechanical pain are first detected at our largest sensory surface, the skin. The cell bodies of sensory neurons that detect such stimuli are located in the dorsal root ganglia, and subtypes of these neurons are specialized to detect specific modalities of mechanical stimuli. ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature05394
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  • 7
    Electronic Resource
    Electronic Resource
    Thickness and angular dependencies of exchange bias in ferromagnetic/antiferromagnetic bilayers (2002)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 92 (2002), S. 1009-1013 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A generalized Meiklejohn–Bean model in which the exchange coupling includes bilinear (direct exchange) and biquadratic (spin–flop) terms is proposed to study the exchange bias in ferromagnetic (FM)/antiferromagnetic (AFM) bilayers. For the strong antiferromagnetic anisotropy, an explicit formula for the exchange bias is derived and used to discuss the thickness and angular dependencies, and a lot of recent experimental results can thus be illustrated. The results show that both the critical thickness of the antiferromagnetic layer displaying the exchange bias and the saturation value of the exchange bias depend on the exchange coupling constants, the angle between the FM easy axis and AFM easy axis, as well as the orientation of an applied field. The bilinear and biquadratic terms will provide competitive contributions to the exchange bias, while the angular variation of the applied field can tune the exchange bias. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1486020
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  • 8
    Electronic Resource
    Electronic Resource
    Ferromagnetic resonance and exchange anisotropy in ferromagnetic/antiferromagnetic bilayers (2002)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 91 (2002), S. 2180-2185 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In this article, we study the in-plane ferromagnetic resonance (FMR) and exchange anisotropy in a ferromagnetic (FM)/antiferromagnetic (AFM) bilayer. In the semi-infinite limit for the AFM layer, the equilibrium energy for the system is established, and then analytical expressions are derived for FMR frequency, frequency linewidth, exchange anisotropy constant, effective exchange bias, and pinning angle. Three physical parameters are important, i.e., the classical exchange bias, the interface turning coefficient, and the applied field angle. Combining the formulas derived with numerical calculation, it is shown that there are two branches of FMR modes distinguished by critical fields which depend on the interface turning the coefficient and the applied field angle. We find that the effective exchange bias depends on the applied field angle but not on its magnitude. A comparison with previously reported theoretical results is made, and experimental measurements for physical parameters are suggested. © 2002 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1433927
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  • 9
    Electronic Resource
    Electronic Resource
    Complexation thermodynamics of bis(crown ether)s. 2. Calorimetric titration of complexation of potassium ion with bis(benzocrown ether)s: enthalpy-entropy compensation (1988)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 92 (1988), S. 2371-2374 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100319a053
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  • 10
    Electronic Resource
    Electronic Resource
    The Galactic distribution of O-rich AGB stars
    Amsterdam : Elsevier
    Chinese Astronomy and Astrophysics 17 (1993), S. 321-326 
    Details
    ISSN: 0275-1062
    Keywords: AGB stars-distribution
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0275-1062(93)90099-B
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