ISSN:
1432-072X
Keywords:
Methylosinus trichosporium
;
Methane Oxidation
;
Metal Ions
;
Metal Binding Components
;
Role of Copper
;
Specific Inhibitors
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Abstract Methane oxidation by washed cell suspensions of Methylosinus trichosporium OB3B was selectively inhibited by 25 compounds, including metal binding components such as carbon monoxide (85% O2: 15% CO), KCN (10-6 M), αα′-dipyridyl (10-4 M), 8-quinolinol (10-4 M), thiosemicarbazide (10-5 M), thiourea (10-5 M), hydroxylamine (10-4 M), histidine (10-2 M), British Anti-Lewisite (5x10-3 M), and miscellaneous known inhibitors of other oxygenases. A role for copper in the methane oxygenase system was suggested by the pattern of inhibition and relief of inhibition by added metal ions.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00428369
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