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  • 1
    Electronic Resource
    Electronic Resource
    Cimetidine as an oral antacid before elective Caesarean section (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 37 (1982), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The H2-receptor antagonist cimetidine was used as a pre-operative antacid in 64 women scheduled for elective Caesarean section. All were given cimetidine 400 mg 90–215 minutes before induction, with 20 of them having an extra 400 mg dose the previous night. The intragastric pH at induction of anaesthesia was reliably above 2.5 if the treatment was given 90 150 minutes beforehand. The volume of gastric contents was reduced when compared with a control series of women receiving either no pre-operative antacid or 30 ml magnesium trisilicate mixture BPC. No adverse effects on mothers or infants were detected.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1982.tb00989.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    High frequency jet ventilation (1984)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 39 (1984), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: A case is described where high frequency jet ventilation was used to avoid the cardiovascular depressant effects associated with conventional ventilation. Early weaning from inotropic and ventilatory support proved possible.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1984.tb09508.x
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  • 3
    Electronic Resource
    Electronic Resource
    A field trial of cimetidine as the sole oral antacid in obstetric anaesthesia (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Anaesthesia 37 (1982), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Cimetidine was used as the routine antacid treatment for 1323 parturients. The findings from 70 of those who needed an emergency general anaesthetic are reported. Once sufficient time had elapsed for absorption of the drug, and provided that the dosage regime was adhered to, 96% of the women studied had an intragastric pH above 2.5. Neonatal monitoring revealed no abnormalities related to the cimetidine treatment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.1982.tb00990.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Cimetidine in labour: absence of adverse effect on the high-risk fetus (1985)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 92 (1985), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary. In a prospective randomized trial, 36 women received cimetidine and 32 magnesium trisilicate mixture BP as antacid therapy every 2 h in labour. The women belonged to a high-risk category and the infants born were 〈36 weeks gestation, or 〈2000g birthweight or otherwise in jeopardy because of severe maternal pre-eclampsia or diabetes. Measurements of a wide range of haematological and biochemical variables revealed no differences between the two groups of babies. The frequency of complications found in the infants was similar, although infants born to the women who received magnesium trisilicate required oxygen therapy for a longer period. Cimetidine did not appear to affect the development of gastric acidity, or to increase bacterial colonization of the gastrointestinal tract in the infant.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1985.tb01108.x
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  • 5
    Electronic Resource
    Electronic Resource
    Use of methoxamine in the resuscitation of epinephrine-resistant electromechanical dissociation (2001)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 56 (2001), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe three cases of electromechanical dissociation under anaesthesia that were unresponsive to doses of intravenous epinephrine given according to current Advanced Life Support guidelines, but which responded immediately to the intravenous administration of the pure α agonist, methoxamine. We suggest a possible mechanism to explain this finding and review the literature on vasopressor drugs used for cardiopulmonary resuscitation during electromechanical dissociation. An intravenous α agonist, such as methoxamine 20 mg, should be considered for any case of cardiac arrest secondary to electromechanical dissociation which is unresponsive to epinephrine given according to current guidelines.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.2001.2268-2.x
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  • 6
    Electronic Resource
    Electronic Resource
    A reply (2002)
    Oxford, UK : Blackwell Science, Ltd
    Anaesthesia 57 (2002), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2044.2002.2575_21.x
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  • 7
    Electronic Resource
    Electronic Resource
    Propofol sedation using DiprifusorTM target-controlled infusion in adult intensive care unit patients (2004)
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 59 (2004), S. 0 
    Details
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: This multicentre, non-comparative study investigated the range of target blood propofol concentrations required to sedate 122 adult intensive care patients when propofol was administered using DiprifusorTM target-controlled infusion systems together with opioid analgesia. Depth of sedation was assessed with a modified Ramsay score and the target blood propofol setting was adjusted to achieve the sedation desired for each patient. A desired level of sedation was achieved for 84% of the sedation period. In postcardiac surgery patients the median time-weighted average propofol target setting was 1.34 μg.ml−1 (10th – 90th percentiles: 0.79–1.93 μg.ml−1). Values in brain injured and general ICU patients were 0.98 (10th – 90th percentiles: 0.60–2.55) μg.ml−1 and 0.42 (10th – 90th percentiles: 0.16–1.19) μg.ml−1, respectively. Measured propofol concentrations were generally close to values predicted by the DiprifusorTM system. Target settings in the range of 0.2–2.0 μg.ml−1 are proposed for propofol sedation in this setting with titration as required in individual patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2044.2004.03745.x
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  • 8
    Electronic Resource
    Electronic Resource
    Cloning, sequencing and expression of the Schwanniomyces occidentalis NADP-dependent glutamate dehydrogenase gene (1991)
    Springer
    Current genetics 20 (1991), S. 219-224 
    Details
    ISSN: 1432-0983
    Keywords: Schwanniomyces occidentalis ; Expression in Saccharomyces cerevisiae ; NADP-Glutamate dehydrogenase ; DNA sequence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The cloned NADP-specific glutamate dehydrogenase (GDH) genes of Aspergillus nidulans (gdhA) and Neurospora crassa (am) have been shown to hybridize under reduced stringency conditions to genomic sequences of the yeast Schwanniomyces occidentalis. Using 5′ and 3′ gene-specific probes, a unique 5.1 kb BclI restriction fragment that encompasses the entire Schwanniomyces sequence has been identified. A recombinant clone bearing the unique BclI fragments has been isolated from a pool of enriched clones in the yeast/E. coli shuttle vector pWH5 by colony hybridization. The idenity of the plasmid clone was confirmed by functional complementation of the Saccharomyces cerevisiae ghd-1 mutation. The nucleotide sequence of the Schw. occidentalis GDH gene, which consists of 1380 nucleotides in a continuous reading frame of 459 amino acids, has been determined. The predicted amino acid sequence shows considerable homology with GDH proteins from other fungi and significant homology with all other available GDH sequences.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00326236
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Meningococcal septicaemia: treatment with protein C concentrate (2000)
    Springer
    Intensive care medicine 26 (2000), S. 471-473 
    Details
    ISSN: 1432-1238
    Keywords: Key words Meningococcal ; Septicaemia ; Protein C concentrate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Meningococcal septicaemia is a devastating disease with the potential to develop severe vascular complications. The incidence in Northern Ireland has risen from 27 cases notified in 1992 to 56 notified in 1997. We describe the first use of protein C concentrate in addition to antithrombin III infusion in the management of a life-threatening case of meningococcal septicaemia in the Regional Intensive Care Unit, Royal Group of Hospitals, Belfast, UK. The rationale and the evidence to support the use of protein C concentrate are discussed. Despite the apparent efficacy and safety of this treatment, subsequent cases of meningococcal septicaemia have not received protein C concentrate due to a lack of availability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340051184
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  • 10
    Electronic Resource
    Electronic Resource
    Spectrophotometric determination of chromium(III) with 3-thianaphthenoyltrifluoroacetone (1972)
    Springer
    Microchimica acta 60 (1972), S. 321-325 
    Details
    ISSN: 1436-5073
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Ein spektralphotometrisches Verfahren zur Bestimmung von Chrom(III) mit 3-Thianaphthenoyltrifluoraceton bei ph 4,0 bis 4,5 wurde beschrieben. Der Einfluß von pH, Zeit, Lösungsmitteln, Reagenskonzentration und von verschiedenen Fremdionen wurde ermittelt. Das Beersche Gesetz wird erfüllt; der molare Extinktionskoeffizient beträgt 1,3·103.
    Notes: Summary A visible Spectrophotometric method is described for the determination of chromium(III) with 3-thianaphthenoyltrifluoroacetone at a pH of 4.0 to 4.5. The effects due to pH, time, solvents, reagent concentration, and diverse ions are reported. Beer's law is obeyed and the molar extinction coefficient is 1.3·103.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01219825
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