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  • 1
    Electronic Resource
    Electronic Resource
    Ultraviolet Absorption Spectra of Hydrolysis Products of Diethyl Barbituric Acid (1954)
    s.l. : American Chemical Society
    Analytical chemistry 26 (1954), S. 1661-1662 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac60094a041
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  • 2
    Electronic Resource
    Electronic Resource
    Modelling the growth and harvest yield of the giant kelp Macrocystis pyrifera (1987)
    Springer
    Marine biology 95 (1987), S. 611-624 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The giant kelp Macrocystis pyrifera is one of the largest and fastest growing seaweeds and is dominant over large areas of the west coast of North America. A model of its growth has been developed which describes plant biomass and production over the course of a year as a function of environmental parameters which affect the light flux. Such parameters include water clarity, spacing between plants, bottom depth, latitude, harvesting activity, and photosynthetic response (P max and I k ). Model results for a standard set of conditions (latitude 33°N, 3 m plant spacing, water absorbance of 0.115 m-1 and 12 m depth) yield a peak daily gross production of almost 6 g C m-2 d-1, peak daily net production of almost 3 g C m-2 d-1, and a peak specific growth rate of about 0.022 d-1. Annual gross production for this case is 1 567 g C m-2 yr-1; annual net production is 537 g C m-2 yr-1. These values are comparable to those from field measurements. Size and timing of biomass and production peaks are affected by changes in the parameters describing the light field, with peaks usually occurring later in the year for more adverse circumstances. Inhigher latitudes, the seasonal variation is so extreme that the plant could not last the year at 53° N in 12 m of water, although it is able to survive the year in shallower water. Harvesting has severe effects on biomass and production. Model results suggest that light limitation is a very important constraint on kelp growth that should not be overlooked. This implies that differences in parameters describing two environments must be considered when comparing results obtained at different locales.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393105
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  • 3
    Electronic Resource
    Electronic Resource
    Are non-relevant objects represented in working memory? The effect of non-target objects on reach and grasp kinematics (1995)
    Springer
    Experimental brain research 102 (1995), S. 519-530 
    Details
    ISSN: 1432-1106
    Keywords: Prehension ; Reach to grasp ; Working memory ; Visual attention ; Visual feedback ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The role of visual information and the precise nature of the representations used in the control of prehension movements has frequently been studied by having subjects reach for target objects in the absence of visual information. Such manipulations have often been described as preventing visual feedback; however, they also impose a working memory load not found in prehension movements with normal vision. In this study we examined the relationship between working memory and visuospatial attention using a prehension task. In this study six healthy, right-handed adult subjects reached for a wooden block under conditions of normal vision, or else with their eyes closed having first observed the placement of the target. Furthermore, the role of visuospatial attention was examined by studying the effect, on transport and grasp kinematics, of placing task-irrelevant “flanker” objects (a wooden cylinder) within the visual field on a proportion of trials. Our results clearly demonstrated that the position of flankers produced clear interference effects on both transport and grasp kinematics. Furthermore, interference effects were significantly greater when subjects reached to the remembered location of the target (i.e., with eyes closed). The finding that the position of flanker objects influences both transport and grasp components of the prehension movement is taken as support for the view that these components may not be independently computed and that subjects may prepare a coordinated movement in which both transport and grasp are specifically adapted to the task in hand. The finding that flanker effects occur primarily when reaching to the remembered location of the target object is interpreted as supporting the view that attentional processes do not work efficiently on working memory representations.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00230656
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  • 4
    Electronic Resource
    Electronic Resource
    The internal control of action and Parkinson's disease: a kinematic analysis of visually-guided and memory-guided prehension movements (1995)
    Springer
    Experimental brain research 105 (1995), S. 147-162 
    Details
    ISSN: 1432-1106
    Keywords: Prehension ; Reach to grasp ; Working memory ; Visual attention ; Visual feedback ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper reports two experiments which examined the effects of Parkinson's disease (PD) upon the sensorimotor mechanisms used to control prehension movements. Transport and grasp kinematics for visually-guided and memory-guided prehension movements were examined in healthy control subjects and compared against those of patients with idiopathic PD. Two research questions were addressed: (1) Are patients with PD particularly susceptible to distraction by non-relevant objects? (2) Are patients with PD especially reliant on external feedback when executing goal-directed actions? The results indicated that the patient group were no more susceptible to distraction by non-relevant objects than the control group. In contrast, the patients with PD were shown to be significantly, impaired when executing memory-guided reaches. Furthermore, the deficits exhibited by the PD group on memory-guided reaches were confined solely to those markers associated with the transport component of the prehension movement. That is, while both controls and patients with PD widened their grip aperture on memory-guided trials, the magnitude of this adjustment was comparable across the two groups. The implications of these findings for theories of visuomotor processing in sufferers of PD and the control of prehension movements more generally are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00242190
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  • 5
    Electronic Resource
    Electronic Resource
    The influence of initial hand posture on the expression of prehension parameters (1998)
    Springer
    Experimental brain research 119 (1998), S. 9-16 
    Details
    ISSN: 1432-1106
    Keywords: Key words Hand posture ; Prehension ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  This paper describes the transport and grasp kinematic parameters associated with four initial hand postures (palm flat and thumb against the hand, palm flat and thumb extended laterally, index and thumb in opposition, and index and thumb in opposition and elbow flexed 90°). A group of healthy adult subjects reached for and picked up a wooden dowel placed midsagittally, at one of three distances (20 cm, 25 cm and 30 cm). The initial posture of the hand and arm altered transport (peak velocity and peak negative acceleration) as well as grasp (peak angle and time to peak angle) parameters, particularly when the elbow was flexed 90°. The pattern of results was reproduced in a pointing paradigm. The findings are discussed in the context of joint space models of reaching.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002210050314
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  • 6
    Electronic Resource
    Electronic Resource
    The appropriate dosage regime for the transition from intravenous lignocaine to oral tocainide after acute myocardial infarction (1983)
    Springer
    European journal of clinical pharmacology 25 (1983), S. 589-594 
    Details
    ISSN: 1432-1041
    Keywords: Tocainide ; Lignocaine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary To define the appropriate regime for the transition from intravenous lignocaine to oral tocainide after uncomplicated acute myocardial infarction, 43 patients received lignocaine to steady state. Each patient then received a tocainide dosage schedule. Plasma concentration of lignocaine and tocainide was measured frequently until the third peak plasma tocainide level. Tocainide 400 mg 8 hourly starting 4 h before cessation of lignocaine and tocainide 400 mg 4 hourly starting at the end of the infusion produced therapeutic plasma tocainide concentration (3.5–9 mg/l) only after the second dose. Tocainide 600 mg 12 hourly starting 6 h before cessation of lignocaine and tocainide 600 mg 6 hourly starting at the end of the infusion quickly achieved therapeutic plasma tocainide concentration which declined to give subtherapeutic first dose troughs of 2.42 mg/l (±0.28 SEM) and 2.79 mg/l (±0.27 SEM) respectively. Consistently therapeutic plasma tocainide concentrations were achieved by both of these regimes after the second dose. The short plasma halflife of lignocaine which for these regimes was 3.71 h (±0.25 SEM), resulted in subtherapeutic lignocaine concentrations before consistently therapeutic plasma tocainide concentrations had been achieved. On the basis of these results, the 600 mg 6 hourly tocainide dosage schedule was studied with cessation of lignocaine infusion either two or six h after the first tocainide dose. With the former regime only three of 5 patients had therapeutic lignocaine at the subtherapeutic tocainide trough. When lignocaine was discontinued on administration of the second tocainide dose however, therapeutic lignocaine concentration was maintained in all patients until tocainide was rising within the therapeutic range. The latter regime, which we would recommend, was not accompanied by increased side effects. Steady state tocainide was found to be present 12 h after the third tocainide dose allowing continued therapy with tocainide 600 mg 12 hourly.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00542344
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  • 7
    Electronic Resource
    Electronic Resource
    24-hour control of blood pressure by once daily doxazosin: a multicentre double-blind comparison with placebo (1988)
    Springer
    European journal of clinical pharmacology 34 (1988), S. 613-618 
    Details
    ISSN: 1432-1041
    Keywords: doxazosin ; hypertension ; alpha1-adrenoceptor inhibitor ; adverse effects ; multicentre study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The antihypertensive efficacy of the new, once daily, alpha1-adrenoceptor inhibitor, doxazosin, was compared with placebo in 40 patients with mild to moderate hypertension. Following a dose titration the mean final daily doxazosin dose in 20 patients was 13.1 mg. Through-the-day blood pressure control was assessed by frequent measurements during 24 h hospitalisation in the 9 th week of double-blind treatment compared with similar measurements made during a 2 week single-blind placebo run-in. Mean reductions in standing and supine systolic and diastolic blood pressure during doxazosin treatment were statistically significantly greater than during placebo treatment at most hourly time points during the 24 h post-dose period. Twenty-four post-dose the mean falls in standing and supine diastolic blood pressure during doxazosin treatment were statistically significant when compared with placebo. Adverse effects during doxazosin treatment were generally minor and were tolerated or disappeared with continued therapy. No patients were withdrawn from the study due to adverse effects. We conclude that once daily doxazosin provides smooth and effective blood pressure control throughout a 24 h post-dose period.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00615226
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  • 8
    Electronic Resource
    Electronic Resource
    Visible spectroscopy surveys of the OHTE plasma (abstract) (1985)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 869-869 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A Jarrell-Ash 0.27-m triple grating spectrometer with a high-speed intensified diode array detector has been used to perform time-resolved surveys of the visible emission (2200-7000 A(ring)) from the OHTE plasma. Using a 512 diode array, spectra are obtained every 516 μs during the shot. The spectral width of the scan is 150, 300, or 1200 A(ring) depending on the grating selected. Surveys at up to 500 kA for OHTE plasmas indicate a complete absence of metal emission lines with the graphite bead vacuum liner. In the 5200-A(ring) region, a clear iindow has been identified for optical bremsstrahlung measurements. Other details of the spectra will be discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1138079
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  • 9
    Electronic Resource
    Electronic Resource
    1-m normal incidence UV spectrometer for plasma measurements (abstract) (1985)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 56 (1985), S. 870-870 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: An Acton Research VM 521-SG UV monochromator has been equipped with an intensified diode array detector for use as a mid-UV spectrometer. 600 and 2400 gr/mm gratings are used in a turret assembly for either low-resolution surveys or high-resolution Doppler ion studies. The detector is a CsI coated MCP with a P-11 output phosphor. The 1024 diode array is scanned at a 1-MHZ video rate allowing a complete spectra to be obtained in 1.0 ms. System performance and preliminary operation on the OHTE plasma will be presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1138080
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Hard-to-Cook Phenomenon in Beans: Effects of Accelerated Storage on Water Absorption and Cooking Time (1981)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 46 (1981), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Black beans stored for 7–14 days at 41°C, 100% RH, required more cooking time than fresh beans and thus paralleled cooking time for beans stored forr more than 1 yr at room temperature. With corrections for solids lost during soaking, water absorption did not differ between fresh and stored beans. The rate of electrolyte leakage was greater from stored beans than from fresh samples, indicating that the cotyledon deteriorated during aging. Bean moisture content was found to be related to cooking time. In general, the higher the moisture content after soaking, the shorter the cooking time. However differences in cooking times between fresh and aged samples persisted regardless of bean moisture content.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1981.tb15351.x
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