ISSN:
1573-8671
Keywords:
Image processing
;
atomic force microscopy
;
scaling index
;
DNA
;
plasmid
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Computer Science
,
Natural Sciences in General
Notes:
Abstract The scaling index method was used in order to analyze atomic force microscopic images of double-stranded DNA (plasmid PUC 8) adsorbed to mica. With this algorithm, the image can be decomposed into constituents of different dimensionality, i.e., point-like, thread-like, and area-like structures, and residual noise. Special focus is on the evaluation of this method for the future automated analysis of binding events of DNA-specific proteins.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1023/A:1023372420594
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