ISSN:
1476-4687
Source:
Nature Archives 1869 - 2009
Topics:
Biology
,
Chemistry and Pharmacology
,
Medicine
,
Natural Sciences in General
,
Physics
Notes:
[Auszug] The nucleic-acid-binding domain of TFIIS (C-terminal resi-dues 231-280) contains a novel Cys4 Zn2+-binding site that is required for activity10. In its absence, TFIIS fragments retain RNAPII binding but inhibit (rather than stimulate) elongation. Nucleic-acid binding is not exhibited by the intact ...
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1038/365277a0
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