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  • 1
    ISSN: 1520-5002
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 321-323 (Oct. 2006), p. 1447-1450 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: The magnetic camera using magnetic lens is proposed to satisfy the demands such asobtaining the distribution of the magnetic flux leakage (DMFL) on the high lift-off, and improvingsensitivity. However, DMFL is strongly affected by the magnetization direction. Therefore, theDMFL has low intensity when the crack is not perpendicular to the magnetizing direction. Also,quantitative nondestructive evaluation would be difficult. This paper proposes an improvedmagnetization method to evaluate a crack quantitatively, regardless of the crack direction. Thesecondary magnetic source, which is perpendicular to the primary magnetic source, is introduced inthe scan type magnetic camera. The intensity of two values of ∂B/∂x (1st differential to themagnetization direction) of the DMFL can be used to evaluate the crack volume. The experimentaland the numerical analysis results are considered to verify this phenomenon
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 321-323 (Oct. 2006), p. 1451-1456 
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Magnetic-optical film (hereafter, MO film) is a bismuth-doped iron garnet film grown on agadolinium gallium garnet substrate by liquid phase epitaxial method. Because an MO film hasphysical characteristics such as Faraday rotation and magnetic anisotropy, the distribution of itsexternal magnetic field can be visualized. The MOI (Magneto-Optic/Eddy Current Imager) wasdeveloped to detect far-side cracks and corrosions in aluminum alloy materials on an aircraft. Thedetection probability of 2.5mm-length cracks is 90/95% when the MO film and the induced areacurrent are used. However, the quantitative evaluation algorithm for quantifying crack shapes andsizes has yet to be proposed. This paper investigates a quantitative evaluation algorithm for magneticoptical eddy current imaging by using the finite element analysis methods (FEM) and experimentalresults. The MOI including a primary induction coil was simulated by FEM software. The position,depth, shape, and the induction current frequency, lift-off were simulated and examined. A simplifiedquantitative evaluation algorithm for MOI is proposed by using the analysis results
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 544-545 (May 2007), p. 91-94 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: We analyzed the effects of several process variables on removal efficiencies of NO andSO2 by the low temperature plasma process combined with photocatalysts. The cylinder-wire type,dielectric barrier discharge process for plasma generation was used. The photocatalysts were coatedonto the glass beads by dip-coating method. As the voltage applied to the plasma reactor increases,or as the pulse frequency of applied voltage increases, the NO and SO2 removal efficiencies alsoincrease. As the initial NO concentration decreases, or as the residence time increases, the NO andSO2 removal efficiencies increase
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of neurochemistry 59 (1992), S. 0 
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The biochemical mechanisms involved in neurite outgrowth in response to nerve growth factor (NGF) have yet to be completely resolved. Several recent studies have demonstrated that protein kinase activity plays a critical role in neurite outgrowth. However, little information exists about the role of protein phosphatases in the process. In the present study, okadaic acid, a phosphatase inhibitor (specific for types 2A and 1) and tumor promoter, was used to investigate the role of protein phosphatases in neurite outgrowth in PC12 cells. PC12 cells cultured in the presence of 50 ng/ml of NGF started to extend neurites after 1 day. After 3 days, 20–25% of the cells had neurites. Okadaic acid inhibited the rate of neurite outgrowth elicited by NGF with an IC50, of sim7 nM. This inhibition was rapidly reversed after washout of okadaic acid. Okadaic acid also enhanced the neurite degeneration of NGF-primed PC12 cells, indicating that continual phosphatase activity is required to maintain neurites. Taken together, these results reveal the presence of an okadaic acid-sensitive pathway in neurite outgrowth and imply that protein phosphatase plays a positive role in regulating the neuritogenic effects of NGF.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Chinese Astronomy and Astrophysics 8 (1984), S. 354-356 
    ISSN: 0275-1062
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Combinatorica 12 (1992), S. 389-410 
    ISSN: 1439-6912
    Keywords: 03 B 10 ; 05 C 60 ; 05 C 85
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract In this paper we show that Ω(n) variables are needed for first-order logic with counting to identify graphs onn vertices. Thek-variable language with counting is equivalent to the (k−1)-dimensional Weisfeiler-Lehman method. We thus settle a long-standing open problem. Previously it was an open question whether or not 4 variables suffice. Our lower bound remains true over a set of graphs of color class size 4. This contrasts sharply with the fact that 3 variables suffice to identify all graphs of color class size 3, and 2 variables suffice to identify almost all graphs. Our lower bound is optimal up to multiplication by a constant becausen variables obviously suffice to identify graphs onn vertices.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    The @electronic library 22 (2004), S. 269-273 
    ISSN: 0264-0473
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Information Science and Librarianship
    Notes: Nowadays, available music information is increasing rapidly from fast growing digital libraries and the Internet. How to effectively retrieve music data is a challenging task and content-based retrieval of music is a relatively large area. Much work that aims at creating acoustical waveforms of music has been carried out. But to many people, the most important and useful feature of music is the melody. This paper focuses on the melody-based retrieval of music, which can be regarded as a kind of content-based retrieval of music but much closer to the actual nature of music. It can be divided into three parts for studying: the extraction of melodic attributes, the melody input methods and the matching methods.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Bradford : Emerald
    Online information review 28 (2004), S. 367-370 
    ISSN: 1468-4527
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Information Science and Librarianship
    Notes: The importance of electronic theses and dissertations and the Networked Digital Library of Theses and Dissertations has been widely realized by Chinese academic libraries in recent years. This paper introduces the China Networked Digital Library of Theses and Dissertations project initiated by the China Academic Library and Information System and current research into related technologies, including metadata standards, OAI metadata harvesting protocol, standard document format and intellectual property protection. Research work on multilingual and cross-lingual searching, personalization and knowledge organization is also described. The goals of the China Networked Digital Library of Theses and Dissertations are to establish electronic theses and dissertations collections for Chinese academic universities, to provide services to access them efficiently, and to ensure the seamless organization of distributed electronic theses and dissertations collections.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1573-904X
    Keywords: in vitro permeability ; intestinal drug transport ; iron chelator ; solubility ; lipophilicity ; oral absorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Purpose. The in vitro and in situ transport of CGP 65015 ((+)-3-hydroxy-1-(2-hydroxyethyl) -2-hydroxyphenyl-methyl-1 H-pyridin-4-one), a novel oral iron chelator, is described. The predictive power of these data in assessing intestinal absorption in man is described. Methods. Caco-2 epithelial monolayer and in situ rat jejunum perfusion intestinal permeability models were utilized. In vivo iron excretion and preliminary animal pharmacokinetic experiments were described, lonization constants and octanol/aqueous partition coefficients were measured potentiometrically. Solubilities and intrinsic dissolution rates were determined using standard procedures. Results. Caco-2 cell (Papp ∼ 0.25 X 10−6 cm.s−1) and rat jejunum (Pw ∼ 0.4) permeabilities of CGP 65015 were determined. The log D(pH 7.4) of CGP 65015 was 0.58 and its aqueous solubility was 〉 0.5 mg.ml−1 (pH 3−9). The intrinsic dissolution rate of CGP 65015 in USP simulated intestinal fluid was 0.012 mg.min−1.cm−2. CGP 65015 promotes iron excretion effectively and dose dependently in animals. Conclusions. Caco-2 and rat intestinal permeabilities predict incomplete oral absorption of CGP 65015 in man. Preliminary rat pharmacokinetics support this. Physico-chemical data are, also, in line and suggest that CGP 65015 may, in addition, be solubility/dissolution rate limited in vivo. Nevertheless, early animal pharmacological data demonstrate that CGP 65015 is a viable oral iron chelator candidate.
    Type of Medium: Electronic Resource
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