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  • 1
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Industrial management & data systems 105 (2005), S. 137-146 
    ISSN: 0263-5577
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Computer Science , Economics
    Notes: Purpose - This paper aims to examine the effectiveness of computer usage policies in university settings. Design/methodology/approach - Students enrolled in business courses at three midwestern universities were divided, by class, into control and experimental groups. All subjects were asked to complete a survey regarding their awareness of university computer usage policies, consequences of misuse, and methods of policy distribution. The experimental group was exposed to sample computer usage policies. Two weeks later, all subjects were asked to complete the same survey again. Findings - Results suggest that most students have not read their university computer usage policies. However, the presence of a computer usage policy does influence students who have read those policies, but a single exposure is insufficient to influence all subjects. Research limitations/implications - The sample is limited to students from three universities. Practical implications - Written policy statements alone cannot serve as a cornerstone of security; multiple factors must be used to communicate the content of the deterrents. Originality/value - This study notes that the existence of computer usage policies within a university (or organization) does not ensure that all users are familiar with the content of those policies and the penalties imposed for their violation. Providing a copy of computer usage policies to students (or employees) and verbally highlighting major points are not sufficient exposure to eliminate indifference about computer misuse.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Decision sciences 19 (1988), S. 0 
    ISSN: 1540-5915
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Economics
    Notes: There are numerous variable selection rules in classical discriminant analysis. These rules enable a researcher to distinguish significant variables from nonsignificant ones and thus provide a parsimonious classification model based solely on significant variables. Prominent among such rules are the forward and backward stepwise variable selection criteria employed in statistical software packages such as Statistical Package for the Social Sciences and BMDP Statistical Software. No such criterion currently exists for linear programming (LP) approaches to discriminant analysis. In this paper, a criterion is developed to distinguish significant from nonsignificant variables for use in LP models. This criterion is based on the “jackknife” methodology. Examples are presented to illustrate implementation of the proposed criterion.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 58 (1983), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The stability during storage of phosphogluco-isomerase (D-glucose-6-phosphate ketol isomerase EC 5.3.1.9) isoenzymes coded for at the PGI/2 locus has been examined. Extracts were prepared from leaves of several diploid and tetraploid Italian (Lolium multiflorum Lam.) and perennial (Lolium perenne. L.) ryegrass cultivars, as well as from interspecific hybrids. It was clearly demonstrated that extracts from plants homozygous for a specific PGI/2 allele could quickly generate new band forms upon storage. The novel forms were not due to aggregation or disintegration of the original enzyme molecule, and some of the generated bands electrophoresed to gel positions characteristic of other alleles of the same locus. An assessment was also made of the effects of a range of compounds added to the storage buffer. The most likely explanation was that the observed changes were due to the action of proteases, and the implications, especially for those using isoenzymes as genetic markers, are discussed.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 63 (1985), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The Michaelis constants (Km) and activation energies (Ea) for allozymes of cytosolic phosphogluco-isomerase (PGI-2; EC 5.3.1.9) from ryegrasses (Lolium perenne L., Lolium multiflorum Lam. and interspecific hybrids) have been investigated. Differences were found between the allelic isozymes, but intra-allelic variations were at least as large. The thermal stability of the isozymes also varied, with the most commonly occurring form (the b-allozyme) having the highest stability at 50°C. Some possible explanations for these findings are discussed and the implications for plant breeders outlined.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Physiologia plantarum 60 (1984), S. 0 
    ISSN: 1399-3054
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology
    Notes: The development of isozymes of phosphogluco-isomerase (PGI; D-glucose-6-phosphate ketol isomerase EC 5.3.1.9.) in perennial ryegrasses was followed from dry seed through to leaf senescence using starch gel electrophoretic separations. Root isozymes were also examined. Two forms of the enzyme were found, one (PGI/2) being present in all tissues and at all stages of the life cycle. The other (PGI/1) had two zones of activity, one of which was detected only in light-exposed tissue. Normal development of this form could be inhibited by growing seedlings on distilled water. Some alleles of PGI/2 not previously reported for ryegrasses are also described.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Bingley : Emerald
    Industrial management & data systems 96 (1996), S. 3-10 
    ISSN: 0263-5577
    Source: Emerald Fulltext Archive Database 1994-2005
    Topics: Computer Science , Economics
    Notes: The area of computer abuse and professional ethics in computing is of interest to companies as well as ethics researchers. Expands the research in ethical behaviour of information system employees. Identifies empirically a few demographic variables that are associated with the ethical behaviour of information system (IS) personnel and raises a few issues for IS managers. In addition, indicates that the existing models of ethical behaviour, when used in the computing context, need to be suitably modified by including demographic variables.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract The processes of atrazine (2-chloro-4-[ethylamino]-6-[isopropylamino-]-s-tri-azine) uptake and release in the submersed vascular plant,Potamogeton perfoliatus L., were rapid, approaching equilibrium with the surrounding environment within one hr. The ratio of internal atrazine concentration to external concentration was approximately 10 at the point of maximum photosynthetic inhibition and rapidly increased at lower external atrazine concentrations. The I50 (the concentration inhibiting photosynthesis by 50%) for atrazine in solution was 80 μg/L with the maximum observed photosynthetic reduction (87%) at a solution concentration of 650 μg/L. Initial photosynthetic recovery ofP. perfoliatus following exposure to atrazine was rapid with oxygen evolution from treated plants (5, 25, and 100 μg/L) being statistically indistinguishable from control plants after two hr of atrazine-free wash. However, there was an indication of residual photosynthetic depression in dosed plants, even after a 77 hr recovery period. In Chesapeake Bay, potential long-term exposure of submersed plants to concentrations of atrazine greater than 10 μg/L is doubtful so that reduction ofP. perfoliatus photosynthesis under such conditions would be minimal and reversible.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    New York, NY [u.a.] : Wiley-Blackwell
    Journal of Cellular Physiology 161 (1994), S. 293-302 
    ISSN: 0021-9541
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Medicine
    Notes: Addition of the nephrotoxic cysteine conjugate, S-(1, 2-dichlorovinyl)-L-cysteine (DCVC), to the LLC-PK1 line of renal epithelial cells leads to covalent binding of reactive intermediates followed by thiol depletion, lipid peroxidation, and cell death (Chen et al., 1990, J. Biol. Chem., 265:21603-21611.) The present study was designed to determine if increased intracellular free calcium might play a role in this pathway of DCVC-induced toxicity by comparing the temporal relationships among increased intracellular free calcium, lipid peroxidation, and cytotoxicity. Intracellular free calcium increased 1 hr after DCVC treatment, long before LDH release occurred. The elevation of intracellular free calcium and cytotoxicity was prevented by inhibiting DCVC metabolism with AOA. The cell-permeable chelators, Quin-2AM and EGTA-AM, prevented the toxicity. Pretreatment of cells with a nontoxic concentration of ionomycin increased intracellular free calcium and potentiated DCVC-induced LDH release. However, the antioxidant, DPPD, which blocks lipid peroxidation and toxicity, did not affect the increase in intracellular free calcium, whereas buffering intracellular calcium with Quin-2AM or EGTA-AM blocked both lipid peroxidation and toxicity without preventing the depletion of nonprotein sulfhydryls by DCVC. Ruthenium red, an inhibitor of mitochondrial calcium uptake, also blocked cell death. We hypothesize that covalent binding of the reactive fragment from DCVC metabolism leads to deregulation of intracellular calcium homeostasis and elevation of intracellular free calcium. Increased intracellular free calcium may in turn be coupled to mitochondrial damage and the accumulation of endogenous oxidants which cause lipid peroxidation and cell death. © 1994 Wiley-Liss, Inc.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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