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  • 1
    Electronic Resource
    Electronic Resource
    Rough endoplasmic reticulum in the adrenaline and noradrenaline cells of the adrenal medulla: Effects of intracranial surgery and pinealectomy (1992)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of pineal research 12 (1992), S. 0 
    Details
    ISSN: 1600-079X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Adrenal medullas in 53-day-old rats of the nonoperated (NO) group (n = 31), the sham-operated (SPX) group (n = 35) and the pinealectomized (PX) group (n = 38) were examined electron microscopically 14 days after surgery. Cell profiles showing solitarily and sparsely distributed rough endoplasmic reticulum (RER) were most frequent in the PX group (daily mean: 66.9%, 427/638), less in the NO (56.0%, 336/600), and least in the SPX (48.5%, 297/612) in adrenaline (A) cells (x2-test: P 〈 0.001), while most frequent in the NO group (68.8%, 340/494), less in the PX (64.3%, 303/471), and least in the SPX (57.4%, 256/446) (P 〈 0.005) in noradrenaline (N) cells. Individual variation was less in A cells than in N cells. Cell profiles showing a large accumulation of RER was more frequent in A cells (N0:8.5%, SPX:13.1%, PX:7.7%) than in N cells (NO:2.8%, SPX:4.5%, PX:4.7%) (controls: P 〈 0.001). Sham pinealectomy increased a large accumulation of RER in A cells (P 〈 0.02) and a small aggregation of RER in N cells (P 〈 0.005) with opposite effects of pinealectomy (P 〈 0.005, P 〈 0.025). Pinealectomy decreased a small aggregation of RER without effects of sham pinealectomy in A cells (P 〈 0.001). Conclusions: (1) Accumulation or aggregation of RER in adrenomedullary chromaffin cells was influenced from the pineal gland either as or without effects of intracranial surgery, and (2) RER in adrenomedullary chromaffin cells showed differences due to cell types.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-079X.1992.tb00032.x
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  • 2
    Electronic Resource
    Electronic Resource
    Postnatal observations on the diurnal rhythm and the light-responsiveness in the pineal glycogen content in miceSupported in part by a grant from Japanese Ministry of Education (977001, 1974). (1975)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 183 (1975), S. 39-46 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In mice of both sexes ranging in age from five days to two years, the development and time course of diurnal rhythm and light-related variations in pineal glycogen were systematically studied by a semiquantitative histochemical method. When the animals were maintained under the usual diurnal lighting conditions (12L:12D), the diurnal rhythm and light-related changes in pineal glycogen appeared first at 22 days of age and persisted until two years. The glycogenic response was most prominent between 60 and 150 days, and declined slightly in mice older than one year.The glycogenic response and cell size tended to differ in the distal, middle and proximal portions of the body of the pineal. These regional differences changes with the ages of the animals.When mice were kept in continuous darkness for seven days starting from 15, 23 or 60 days of age, the pineal showed a diurnal rhythm in pineal glycogen.When mice were kept in altered light regimens such as continuous darkness, continuous lighting or 6L:6D from birth up to 30 days, no diurnal variation in pineal glycogen developed.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091830105
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  • 3
    Electronic Resource
    Electronic Resource
    Effect of continuous darkness on diurnal rhythm in glycogen content in pineal cells of the mouse: A semiquantitative histochemical study (1974)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 179 (1974), S. 405-410 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The effect of continuous darkness on diurnal variation of glycogen content in pineal cells of adult mice was investigated by means of a semiquantitative histochemical method. In dark-maintained mice, a diurnal rhythm in pineal glycogen content persisted for the first 7 days of darkness. After 14 days or longer of continuous darkness, however, a clear relationship between the glycogen content and time of day became less apparent. Reversed conditions of environmental lighting caused a complete reversal of the glycogen rhythm in the pineal as early as the fifth day. When mice that had been kept in reversed conditions of lighting for 7 days were exposed to continuous darkness, the reversed glycogen rhythm also persisted in darkness of 7 and 14 days, but it was abolished by darkness of 28 days. The nuclear density of pineal cells was significantly lower at 9 am than at 9 pm in controls. In dark-maintained mice, however, no significant diurnal variation in pineal cell size was generally evident except 2 and 3 days after the initiation of darkness.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091790310
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  • 4
    Electronic Resource
    Electronic Resource
    Effects of continuous lighting on glycogen in the pineal cells of the mouse: A quantitative histochemical study (1971)
    Springer
    Cell & tissue research 118 (1971), S. 214-220 
    Details
    ISSN: 1432-0878
    Keywords: Pineal cells ; Mouse ; Glycogen ; Quantitative histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Effects of continuous lighting on glycogen in pineal cells of the mouse were histochemically investigated, qualitatively and quantitatively. In continuous lighting, glycogen stores in pineal cells show a striking increase during the first three days. The glycogen level rises almost fourfold in 1 day of lighting and reaches a peak at 2 days. At 3 days it begins to decrease slightly. After 3 days the glycogen level decreases gradually until it returns almost to normal in 3 weeks. Continuous lighting causes a decrease in the size of pineal cells, and the decreased size of the cells remains almost constant throughout lighting. In blinded mice, neither glycogen stores in pineal cells nor sizes of pineal cells are affected by continuous lighting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00341565
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  • 5
    Electronic Resource
    Electronic Resource
    Diurnal changes in glycogen content in the pineal cells of the male mouse (1971)
    Springer
    Cell & tissue research 118 (1971), S. 310-314 
    Details
    ISSN: 1432-0878
    Keywords: Pineal ; Mouse ; Glycogen ; Diurnal changes ; Quantitative histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The amount of glycogen in pineal cells of 60-day-old male dd-mice was estimated at various times of the day by means of a quantitative histochemical method. The level of glycogen stores varied periodically in correlation with the environmental light-dark cycle, being lowest at the end of the daily dark period and highest at the end of the daily light period. The size of pineal cells also varied diurnally, being largest at 9 AM, two hours after the beginning of the daily photoperiod, and smallest at 9 PM, two hours after the end of the daily photoperiod; however, these changes were less marked than those in glycogen level. The changes in cell size were delayed by a few hours as compared with changes in glycogen stores. In blinded male mice of the same age, neither pineal glycogen level nor pineal cell size varied in response to diurnal lighting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00331189
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