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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Medical molecular morphology 26 (1993), S. 65-75 
    ISSN: 1860-1499
    Keywords: Ultrastructure ; Rats ; Muscle spindles ; Immobilization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The ultrastructure of rat muscle spindles was examined after the anterior tibial muscles had been immobilized in a plaster cast. There was an increase in the number of collagen fibrils and external laminae around the outer capsules and in the intracapsular space 2 weeks after immobilization. The changes in the intrafusal muscle fibers within 4 weeks included disorientation of myofilaments. After 6 weeks, Z bands had become disarranged, and there was vacuolar degeneration of the sarcoplasmic reticulum in some fibers. Myelin sheaths of many of the myelinated nerve fibers (especially the thick ones, which were probably sensory nerve fibers) had degenerated within 2 weeks. These results indicate that immobilization of skeletal muscles affects not only extrafusal muscle fibers but also the structure of the muscle spindle.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1860-1499
    Keywords: Anterior eruciate ligament reconstruction ; Collagen fibril ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract An ultrastructural study was undertaken concerning morphological changes within the autografted patellar tendon (PT) after being transplanted to the anterior cruciate ligament (ACL) in mongrel dogs. After 4 weeks, the arrangements of both large and small collagen fibrils in the PT graft became disordered, and the number of inflammatory cells increased. However, the same PT grafts revealed postsurgical signs of newly-produced collagen fibrils around activated fibroblasts at 12 to 24 weeks. At 52 weeks after the transplantation, small collagen fibrils increased in both number and density, showing a remarkable morphological similarity to the collagen fibrils of normal ACL. These data indicate that the characteristics of the PT graft eventually resemble those of a normal ACL.
    Type of Medium: Electronic Resource
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