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  • 1
    ISSN: 1435-1463
    Keywords: High-speed memory scanning ; Parkinson's disease ; parkinsonian motor symptoms ; levodopa treatment ; depression ; bradyphrenia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary High-speed memory scanning (Sternberg paradigm) was tested in a collective of 20 parkinsonian patients (10 newly diagnosed, untreated patients, duration of the disease 0.5–3.8, mean 1.5 years; 10 levodopa-treated patients, duration of the disease 4.2 to 11, mean 7.6 years). The levodopa-treated patients stopped taking levodopa before the test. There was a tendency towards retarded memory scanning in the patients' collective compared with 20 healthy controls with similar ages and verbal IQs (p=0.076, Mann-Whitney U test). The mental slowing correlated significantly with bradykinesia and the sum-score of the Columbia University Parkinson Rating Scale (p=0.021 and 0.019; Spearman rank correlation). Kruskal-Wallis ANOVA revealed a significant mental slowing in the subgroup of patients with Parkinson's disease for 〉4 years compared with the newly diagnosed patients and the controls (H=8.54; p=0.019 and 0.006, Mann-Whitney U test). The findings suggest a mental slowing in Parkinson's disease, which is associated with the progression of parkinsonian motor symptoms and not with depression.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1459
    Keywords: Parkinson's disease ; Visuoperception ; Visuospatial cognition ; Age ; Disease severity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Forty patients with Parkinson's disease were compared with 33 normal controls with respect to their performance in the Wechsler Adult Intelligence Scale subtests “information”, “similarities”, “block design”, and “picture completion”, in a test for visual neglect (Hamsher's line cancellation test) and in tests for visuospatial and visuorotational abilities (cube task from Amthauer's intelligence structure test and Rybakoff figure test, as revised by Meili). The findings show that the patients scored significantly worse than the controls (Mann-WhitneyU test,P=0.004) in the Rybakoff figure test, testing visual concept finding, imagination and visual rotation. In the other tests no significant differences were found between the patients and the controls. The deficit of the patients in the figure test of Rybakoff correlated significantly with tremor (P=0.013), akinesia (P=0.009), disability (P=0.043), and age (P=0.004, Spearman rank correlation).
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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