ISSN:
0935-6304
Keywords:
Splitless injection
;
Vaporizing conditions
;
Experimental design
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
Splitless injection conditions were optimized by the use of experimental designs (2-level factorial and central composite designs). Modified parameters were: Type of liner, injection volume, solvent, temperature, splitless time. A prolonged splitless time, considered to be an important parameter, proved to be statistically insignificant. This leads to the conclusion that analytes can penetrate the dead volume between column entrance and split valve. To prevent any penetration of solvents, a small reversed split flow was introduced. It could be shown that this auxiliary flow allows an almost complete transfer of solvents. To further speed up the transfer process, a liner modification was proposed.
Additional Material:
12 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240200403
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