ISSN:
1573-7217
Keywords:
breast cancer detection
;
seasonal variation
;
steroid receptors
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary A significant circannual variation of the month in which patients detect the first sign or symptom of tumour has been defined in 1413 patients with breast cancer. The months of highest detection were in the late springearly summer, and lowest detection was in late autumn-early winter. Analysis of subgroups indicates that this cyclic trend was most significant in younger women with small or moderate-sized tumours containing steroid hormone receptors, particularly progesterone receptors. It seems likely that this variation is related to the effect of cyclic hormonal changes on tumour growth, possibly mediated through the pineal.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01805991
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