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  • 1
    Electronic Resource
    Electronic Resource
    Intra-arterial infusion of papaverine combined with intravenous administration of high-dose nicardipine for cerebral vasospasm (1995)
    Springer
    Acta neurochirurgica 135 (1995), S. 186-190 
    Details
    ISSN: 0942-0940
    Keywords: Cerebral vasospasm ; nicardipine ; papaverine ; subarachnoid haemorrhage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The clinical effect of combination therapy with high doses of intravenous nicardipine and intra-arterial infusion of papaverine on symptomatic vasospasm after subarachnoid haemorrhage (SAH) was analysed retrospectively. In 66 of 122 patients who underwent early aneurysm surgery between 1990 and 1993, the intracranial haemodynamics were documented by transcranial Doppler (TCD) ultrasonography. 33 of these 66 patients received high dose nicar-dipine intravenously (Group I); the other 33 patients were not treated with calcium antagonists (Group II). Symptomatic vasospasm occurred in 6 Group I patients (18%) and in 13 (39%) in Group II patients. All 19 symptomatic patients received an intra-arterial infusion of papaverine; 15 patients (79%) responded well to this therapy and the symptoms were reversed quickly. Although the mean flow velocity (MFV) was not different between the two groups, it was reduced significantly after papverine infusion. Our retrospective analysis suggests that symptomatic vasospasm can be treated effectively with the combination of intravenous high dose nicardipine and intra-arterial infusion of papaverine, and that the correct timing of the infusions is crucial.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02187766
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Arteriovenous malformation and diaschisis (1993)
    Springer
    Acta neurochirurgica 120 (1993), S. 26-32 
    Details
    ISSN: 0942-0940
    Keywords: Arteriovenous malformation ; basal ganglia ; cerebral blood flow ; diaschisis ; thalamus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We investigated the haemodynamic dysfunction and secondary thalamic and brainstem atrophy in 24 patients with angiographically proven cerebral arteriovenous malformations (AVM) and no clinical history of cerebral haemorrhage. Cerebral blood flow (CBF) was measured by the method using either stable Xenon or single photon emission computerized tomography (SPECT). Morphological changes in the thalamus and brainstem were evaluated by magnetic resonance imaging (MRI). Two factors are considered to influence hypoperfusion in the ipsilateral cerebral and contralateral cerebellar hemisphere and secondary atrophy of the thalamus and brainstem. One is the size of the nidus and the other is the involvement of the basal ganglia. It is presumed that continuous haemodynamic stress over a long period of time may cause irreversible histological changes in areas remote from the lesion, especially in the AVM which demonstrates involvement of the basal ganglia or a large nidus.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02001465
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Autoperfusion balloon catheter for treatment of vertebral artery stenosis (1995)
    Springer
    Neuroradiology 37 (1995), S. 561-563 
    Details
    ISSN: 1432-1920
    Keywords: Percutaneous transluminal angioplasty ; Autoperfusion balloon catheter ; Vertebral artery stenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Percutaneous transluminal angioplasty (PTA) of the vertebral artery was performed with an autoperfusion balloon catheter in five patients. There were no complications in the form of embolic episodes or neurological deficits due to brain ischaemia during inflation. In critical cases with insufficient collateral circulation during temporary occlusion, the use of an autoperfusion balloon catheter may expand the indications for PTA in patients with ischaemic cerebrovascular disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593722
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Autoperfusion balloon catheter for treatment of vertebral artery stenosis (1995)
    Springer
    Neuroradiology 37 (1995), S. 561-563 
    Details
    ISSN: 1432-1920
    Keywords: Key words Percutaneous transluminal angioplasty ; Autoperfusion balloon catheter ; Vertebral artery stenosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Percutaneous transluminal angioplasty (PTA) of the vertebral artery was performed with an autoperfusion balloon catheter in five patients. There were no complications in the form of embolic episodes or neurological deficits due to brain ischaemia during inflation. In critical cases with insufficient collateral circulation during temporary occlusion, the use of an autoperfusion balloon catheter may expand the indications for PTA in patients with ischaemic cerebrovascular disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593722
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    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Percutaneous transvenous embolisation of iatrogenic vertebral arteriovenous fistula (1995)
    Springer
    Neuroradiology 37 (1995), S. 400-402 
    Details
    ISSN: 1432-1920
    Keywords: Arteriovenous fistula ; Vertebral artery ; Transvenous occlusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two patients presented with vertebral arteriovenous fistulae following unintentional puncture of the vertebral artery. A percutaneous transvenous approach was used in both cases and the fistula was successfully embolised with microcoils. A complete cure was achieved in both patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588023
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Percutaneous transvenous embolisation of iatrogenic vertebral arteriovenous fistula (1995)
    Springer
    Neuroradiology 37 (1995), S. 400-402 
    Details
    ISSN: 1432-1920
    Keywords: Key words Arteriovenous fistula ; Vertebral artery ; Transvenous occlusion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Two patients presented with vertebral arteriovenous fistulae following unintentional puncture of the vertebral artery. A percutaneous transvenous approach was used in both cases and the fistula was successfully embolised with microcoils. A complete cure was achieved in both patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588023
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    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Histological changes in brain tissue and vasculature after intracarotid infusion of organic solvents in rats (1996)
    Springer
    Neuroradiology 38 (1996), S. 291-294 
    Details
    ISSN: 1432-1920
    Keywords: Key words Liquid embolic agents ; Solvents ; Ethanol ; Dimethyl sulphoxide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Organic solvents, such as ethanol or dimethyl sulphoxide (DMSO), have been used in liquid embolic agents. To investigate the effects of these solvents on the cerebral blood vessels and cerebral tissue, we subjected Wistar rats weighing 250–300 g to internal carotid artery infusion of 0.2 ml diluted ethanol (10 %, 40 % or 70 %) or anhydrous DMSO (100 %). Some rats were sacrificed 5 min after the infusion and the remainder at 10 days. Rats injected with ethanol at high concentration or DMSO showed extensive exudation of Evans blue at the site of injection 5 min after infusion, together with full-thickness necrosis of the wall of vessels and swelling of brain cells. In contrast, rats injected with 10 % or 40 % ethanol solution showed necrosis of only the intimal layer and partial necrosis of the medial layer and no brain swelling was observed. These findings suggest that ethanol at low concentration can be used as a relatively safe solvent for liquid embolic substances.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00596551
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    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Histological changes in brain tissue and vasculature after intracarotid infusion of organic solvents in rats (1996)
    Springer
    Neuroradiology 38 (1996), S. 291-294 
    Details
    ISSN: 1432-1920
    Keywords: Liquid embolic agents ; Solvents ; Ethanol ; Dimethyl sulphoxide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Organic solvents, such as ethanol or dimethyl sulphoxide (DMSO), have been used in liquid embolic agents. To investigate the effects of these solvents on the cerebral blood vessels and cerebral tissue, we subjected Wistar rats weighing 250–300 g to internal carotid artery infusion of 0.2 ml diluted ethanol (10 %, 40 % or 70 %) or anhydrous DMSO (100 %). Some rats were sacrificed 5 min after the infusion and the remainder at 10 days. Rats injected with ethanol at high concentration or DMSO showed extensive exudation of Evans blue at the site of injection 5 min after infusion, together with full-thickness necrosis of the wall of vessels and swelling of brain cells. In contrast, rats injected with 10 % or 40 % ethanol solution showed necrosis of only the intimal layer and partial necrosis of the medial layer and no brain swelling was observed. These findings suggest that ethanol at low concentration can be used as a relatively safe solvent for liquid embolic substances.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00596551
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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