ISSN:
1573-8221
Keywords:
erythroblast receptors
;
macrophages
;
hemopoietic islets
;
erythroid precursors
;
erythrokaryocytes
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract During the preleukemic period, the expression of erythroblast receptors on bone marrow macrophages, the number of neutral red-stained hemopoietic islets and their erythroid and erythrogranulocytic types, and the content of erythrokaryocytes decreased in AKR/JY mice compared with (CBA×AKR/JY) F1 mice. The concentration of erythroid colony-forming units increased. The impairment of qualitative (receptor) and quantitative properties of bone marrow resident macrophages inhibits the differentiation of erythroid cells from committed to mature forms and is probably one of the mechanisms of hypoplasia of the erythroid stem in AKR/JY mice.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02433281
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