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  • 1
    Electronic Resource
    Electronic Resource
    X-ray diffraction and thermal analysis of molybdenum(VI) oxide hemihydrate: monoclinic MoO3.1/2H2O (1983)
    s.l. : American Chemical Society
    Inorganic chemistry 22 (1983), S. 2468-2470 
    Details
    ISSN: 1520-510X
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ic00159a026
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Acute obstructive uropathy —a rare complication of circumcision (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 369-371 
    Details
    ISSN: 1432-1076
    Keywords: Circumcision ; Urinary retention ; Acute renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a rare complication of of ritual circumcision in an 8-week-old boy. He presented 1 week after the procedure with reduced urine output, a grossly distended bladder and marked bilateral hydroureteronephrosis on ultrasonography. The acute partial urinary obstruction was due to the dressing which was applied after surgical removal of the foreskin and to oedema of the glans. He had abnormal renal function (creatinine 85 μmol/l, urea 8.5 mmol/l) and a hyperkalaemic metabolic acidosis with hyponatraemia (Na 127 mmol/l, K 6.9 mmol/l, HCO3 16 mmol/l), which were attributed to obstructive uropathy. Because of prolonged secondary bladder dysfunction he required urinary catheterisation for 1 week. There was significant post obstructive diuresis and parenteral fluid therapy was given for 7 days. Whilst urinary retention is a well recognised complication of circumcision, this is the first report of significant obstructive uropathy and renal impairment due to surgical excision of the foreskin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01956422
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Acute obstructive uropathy – a rare complication of circumcision (1994)
    Springer
    European journal of pediatrics 153 (1994), S. 369-371 
    Details
    ISSN: 1432-1076
    Keywords: Key words: Circumcision – Urinary retention – Acute renal failure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. We report a rare complication of ritual circumcision in an 8-week-old boy. He presented 1 week after the procedure with reduced urine output, a grossly distended bladder and marked bilateral hydroureteronephrosis on ultrasonography. The acute partial urinary obstruction was due to the dressing which was applied after surgical removal of the foreskin and to oedema of the glans. He had abnormal renal function (creatinine 85 µmol/l, urea 8.5 mmol/l) and a hyperkalaemic metabolic acidosis with hyponatraemia (Na 127 mmol/l, K 6.9 mmol/l, HCO3 16 mmol/l), which were attributed to obstructive uropathy. Because of prolonged secondary bladder dysfunction he required urinary catheterisation for 1 week. There was significant post obstructive diuresis and parenteral fluid therapy was given for 7 days. Whilst urinary retention is a well recognised complication of circumcision, this is the first report of significant obstructive uropathy and renal impairment due to surgical excision of the foreskin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310050156
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Computer simulation of adsorption equilibrium for a gas on a solid surface using the potential distribution theory (1986)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 84 (1986), S. 1909-1915 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: Monte Carlo computer simulations of monolayer adsorption of a gas on a solid surface are described in which the potential distribution method was used to directly calculate the adsorption isotherms. The systems studied were the two-dimensional, Lennard-Jones fluid and such a fluid in external potentials chosen to represent the interactions of the adsorbate molecules with exposed faces of an inert fcc crystal. The adsorption isotherms for the structured surfaces show a substantial influence of the surface corrugation upon the adsorption equilibria. The results demonstrate that the potential distribution method is a useful approach to studying adsorption equilibria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.450440
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  • 5
    Electronic Resource
    Electronic Resource
    The rheumatic poison: a survey of some published investigations of the immunopathogenesis of Henoch-Schönlein purpura (1990)
    Springer
    Pediatric nephrology 4 (1990), S. 533-541 
    Details
    ISSN: 1432-198X
    Keywords: Henoch-Schönlein purpura ; Pathogenesis ; Genetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Laboratory studies of the pathophysiology of Henoch-Schönlein purpura (HSP) have become more numerous in recent years with the recognition of the disease's links with the mucosal immune system in general and IgA nephropathy in particular. There are weak genetic associations with C4 null phenotypes and with HLA B35 and DR4. Studies of plasma proteins in HSP patients show an increased IgA concentration, activation of the alternative pathway of complement and consumption of factor XIII. High molecular weight (polymeric) IgA has been detected in affected individuals, which some investigators have called “immune complexes”. Many patients synthesise an IgA rheumatoid factor in the acute phase, but other autoantibodies are largely absent. In vitro studies of lymphocytes from HSP patients have demonstrated an increased number of IgA-bearing and secreting B-cells, with altered T-cell regulation of antibody synthesis. While these observations point to immune dysregulation — primarily of IgA production — as a consistent feature of acute HSP, there is as yet insufficient information available to allow a consistent theory of pathogenesis to be formulated.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00869841
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Pharmacokinetics of cyclosporin in children with stable renal transplants (2000)
    Springer
    Pediatric nephrology 15 (2000), S. 167-170 
    Details
    ISSN: 1432-198X
    Keywords: Key words  Cyclosporin ; Renal transplant ; Pharmacokinetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract   Fourteen children, aged between 5 and 17 years, with stable renal graft function and stable cyclosporin A (CSA) trough levels (Cmin) were studied. They had been taking CSA 12-hourly since their transplant 1.5–9 years previously, with the average dose of Neoral being 6.4 (range 4.4–8.4) mg/kg per day. CSA whole blood levels were measured at 0, 20, and 40 min, and at 1, 1.5, 2, 2.5, 3, 4, 6, and 8 h following the morning dose using the Abbott TDx fluorescence polarization immunoassay. The area under the concentration time curve (AUC), clearance adjusted for bioavailability (CL/F), and steady-state volume of distribution adjusted for bioavailability (Vss/F) were determined using model-independent pharmacokinetic analysis. Delay time (Tdel), peak concentration (Cmax), time to peak concentration (Tmax), and Cmin were also determined and correlated with AUC and other parameters. The Tdel in absorption varied from 0.3 to 1.6 (mean 0.73) h, resulting in a similarly variable time to Tmax of 1–2.4 h (mean 1.59). Tmax was related to the age of the patient (Tmax=0.027age+1.41, r 2=0.56, P〈0.005). The AUC showed good correlation with Cmax (Cmax=0.25AUC+423.32, r 2=0.96, P〈0.0005). Cmax appears to be a more-suitable measure of exposure to CSA than Cmin. Prediction of Tmax from the age of the child may help to overcome the problem of when to collect blood for peak levels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670000325
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  • 7
    Electronic Resource
    Electronic Resource
    Neonatal Bartter syndrome – use of indomethacin in the newborn period and prevention of growth failure (1996)
    Springer
    Pediatric nephrology 10 (1996), S. 756-758 
    Details
    ISSN: 1432-198X
    Keywords: Key words: Neonatal Bartter syndrome ; Indomethacin ; Nephrocalcinosis ; Growth failure ; Hypercalciuria
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Neonatal Bartter syndrome differs from the classical Bartter syndrome in the occurrence of antenatal presentation with polyhydramnios. Nephrocalcinosis and severe growth retardation are common sequelae. Indomethacin has been reported to improve linear growth, but its use in the early newborn period has been infrequently described. In this paper we report normal growth and development and the absence of nephrocalcinosis in an infant now aged 19 months with neonatal Bartter syndrome treated from day 3 of life with indomethacin. With early diagnosis and treatment with indomethacin plus adequate water, calories, and sodium, normal growth can be achieved and nephrocalcinosis may be prevented in children with neonatal Bartter syndrome.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004670050210
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