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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Munksgaard International Publishers
    Allergy 59 (2004), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background: The evaluation and interpretation of the results from blood tests measuring specific immunoglobulin E (IgE) antibody concentration is currently made using the dichotomized result from the test despite a quantitative result is obtained. It has been shown that different levels of IgE antibodies, assessed by blood test and skin prick test, may have a relation to presence of symptoms, implying that there is more information in a quantitative result than in the dichotomous – positive or negative.Objective: To investigate the clinical utility of quantification of IgE antibodies in the diagnosis of allergic patients and whether such procedure has any advantage to the presently dichotomously used sensitivity and specificity at a fixed cut-off.Methods: Data from a previously published study (R. Paganelli, I.J. Ansoteugi, J. Sastre, C.-E. Lange, M.H.W.M. Roovers, H. de Groot, N.B. Lindholm, P.W. Ewan, Allergy, 1998; 53) analysing diagnosis of allergic patients in four different clinics were re-evaluated. In the original study consecutive patients with suspected IgE-mediated allergy had been examined and evaluated according to the clinical routine at each clinic, using case history, physical examination, skin tests and laboratory tests, except the test to be evaluated, and given an ‘doctors’ allergen-specific diagnosis’ as positive or negative. In the present study the relation between ‘doctors’ allergen-specific diagnosis’, expressed as pos/neg, and the quantitative levels of specific IgE antibody concentration was analysed using a logistic regression model. This presentation of results was also compared with the more common characteristics of sensitivity and specificity, and also with Receiver–operator characteristics (ROC) curves.Results: The used logistic model described the relationship between allergen-specific diagnosis in each study and the levels of IgE antibodies. The shape of the curve illustrated the physicians’ disposition for a positive diagnose in the study, in relation to the specific IgE antibody level. Differences in the shape of the curve was found both between allergens within clinics and between clinics for the same allergen. No association could be demonstrated between prevalence and shape of the curve.Conclusions: Conventional sensitivity/specificity figures or ROC concepts only use the qualitative statement of whether IgE is present or not. A risk assessment using the quantitative level of IgE antibody to an allergen increases the utility of the information in clinical context compared with a qualitative statement of whether IgE is present or not. The quantification demonstrated the link between specific IgE antibodies and allergic reactions. The use of objective, well performing quantitative tests should help improve diagnostic accuracy and might provide a way for the patient to understand and manage his or her daily situation and risk for reactions.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Continuous peripheral oxygen saturation monitoring using a finger pulse oximeter is standard in prehospital emergency medicine. Forehead peripheral oxygen saturation monitoring has been enhanced for better performance during movement and in cold ambient temperatures, both of which are common during emergency transport. We compared a new forehead monitor with standard finger pulse oximeter. The forehead technique had significantly fewer mean (SD) alarms per patient (3.0 (2.2)) than the finger pulse oximeter (7.8 (4.0)) and shorter durations of malfunction (76 (60) s compared to 333 (170) s) when using the finger pulse oximeter. We conclude that measuring peripheral oxygen saturation monitoring with a forehead sensor provides better monitoring quality in emergency care.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Summary Motion sickness adds to the discomfort of many patients being transported by ambulance. Recent research has demonstrated the effectiveness of oxygen therapy in reducing motion sickness during transport to hospital. However, patients reported negative reactions to wearing a facemask, which produced feelings of claustrophobia and anxiety. We therefore tested the hypothesis that supplemental oxygen inhaled from a new oxygen delivery device OxyArm™, which avoids direct contact with the patients skin, may reduce the incidence of motion sickness and increase patient satisfaction. Forty patients suffering from minor trauma were included in a prospective, randomised trial. Twenty patients received oxygen administered using a conventional Venturi mask (group 1), and 20 patients received oxygen using the new OxyArm™ device (group 2). Measurements made included oxygen saturation (SaO2), heart rate, systolic and diastolic blood pressures, and patients' subjective score of satisfaction with smell of the device, claustrophobia, inconvenience produced by the oxygen inhalation device and nausea were scored using a visual analogue scale. All patients were haemodynamically stable and comparable between the two groups. Peripheral SaO2 increased in both groups. The scores of nausea and claustrophobia were significantly lower in the OxyArm group, in addition, satisfaction with the OxyArm device was significantly higher. In conclusion, the use of OxyArm™ device produced a lower incidence of motion sickness combined with the additional benefit of greater patient satisfaction, when compared with a conventional facemask, during prehospital transfer of trauma patients.
    Type of Medium: Electronic Resource
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  • 5
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    Unknown
    Berlin : Periodicals Archive Online (PAO)
    Deutsche Zeitschrift für Philosophie. 29:12 (1981) 1494 
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  • 6
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: In the free-radical solution copolymerization of ethylene and vinyl acetate, polymer yield and molecular weight were found to vary considerably with the solvent used. Solvents were toluene, benzene, hexane, heptane, and cyclohexane. Molecular weights were highest in benzene and lowest in toluene and were readily explained by different solvent chain-transfer constants. Polymer yields were highest in aliphatic solvents and lowest in aromatic solvents including benzene. This was attributed to different types of interactions of the solvents with radical species. The saturated aliphatic solvents undergo hydrogen abstraction reactions, but these give reactive alkyl radicals which reinitiate polymer growth. Toluene also undergoes hydrogen abstraction reactions, but the resultant benzyl radical is resonance stabilized and does not readily reinitiate polymerization. Benzene does not undergo hydrogen abstraction reactions. The low yields are attributed to complex formation. A consideration of kinetic theory indicates that complex formation with both initiator and growing polymer radicals is involved. Differences in viscosity, ethylene solubility, and initiator half-life in the different solvents, as well as induced decomposition of the initiator, were not determining factors.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0021-8995
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: The degree of branching of a series of ethylene-vinyl acetate copolymers was found to be strongly dependent upon polymerization temperature. The copolymers were prepared by free-radical polymerization and had low molecular weights and molar ratios of ethylene: vinyl acetate greater than 3:1. Nuclear magnetic resonance and infrared studies showed that copolymers prepared at 150°C were highly branched and had little crystallinity. Branches were mainly alkyl groups on the polymethylene backbone segments. There was no evidence of δ-acetoxyalkyl branches. Long branches originating by intermolecular H abstraction from the acetylmethyl groups were also expected but could not be detected. These results were consistent with an intramolecular “backbiting” mechanism similar to that found in ethylene homopolymerizations. There was little or no participation by the vinyl acetate moiety in the branching scheme. Copolymers prepared at about 90°C had very few long or short branches and were more crystalline. Copolymers prepared between these temperatures had intermediate degrees of branching and crystallinity.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Notfall + Rettungsmedizin 3 (2000), S. 83-85 
    ISSN: 1436-0578
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Ein scheinbarer Routineeinsatz (bewußtlose Person) kann sich bisweilen zu einer komplexen Problematik entwickeln, die weit mehr als medizinisches Wissen erfordert. Es gilt nicht nur dem Notfallpatienten seine Aufmerksamkeit zu widmen, sondern gerade auch nach belastenden Ereignissen die Betreuung der Zeugen nicht zu vergessen.
    Type of Medium: Electronic Resource
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