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Comparative pharmacokinetics of sodium- and methylglucamine diatrizoate in urography (1973)

Taenzer, V. ; Koeppe, P. ; Samwer, K. F. ; [et al.]

Springer

European journal of clinical pharmacology 6 (1973), S. 137-140

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ISSN: 1432-1041

Keywords: Urography ; Hypaque® ; Urovist® ; pharmacokinetics ; renal failure

Source: Springer Online Journal Archives 1860-2000

Topics: Chemistry and Pharmacology , Medicine

Notes: Summary Comparative tests were carried out, using a radioactive tracer method, on the pharmacokinetics of sodium and methylglucamine diatrizoate. A biological model was simulated using an analogue computer; and the rate and elimination constants, the elimination half life, and the ratio of tissue entry to tissue elimination constants were calculated. Over the period of time required for X-ray diagnosis, the two salts of the contrast medium acid which were tested did not alter the pharmacokinetics of the contrast medium itself.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF00562441

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