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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European biophysics journal 24 (1996), S. 311-321 
    ISSN: 1432-1017
    Keywords: Membrane embedded molecules Vesicle shape ; Lateral distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Physics
    Notes: Abstract The interdependence of the lateral distribution of molecules which are embedded in a membrane (such as integral membrane proteins) and the shape of a cell with no internal structure (such as phospholipid vesicles or mammalian erythrocytes) has been studied. The coupling of the lateral distribution of the molecules and the cell shape is introduced by considering that the energy of the membrane embedded molecule at a given site of the membrane depends on the curvature of the membrane at that site. Direct interactions between embedded molecules are not considered. A simple expression for the interaction of the membrane embedded molecule with the local membrane curvature is proposed. Starting from this interaction, the consistently related expressions for the free energy and for the distribution function of the embedded molecules are derived. The equilibrium cell shape and the corresponding lateral distribution of the membrane embedded molecules are determined by minimization of the membrane free energy which includes the free energy of the membrane embedded molecules and the membrane elastic energy. The resulting inhomogeneous distribution of the membrane embedded molecules affects the cell shape in a nontrivial manner. In particular, it is shown that the shape corresponding to the absolute energy minimum at given cell volume and membrane area may be elliptically non-axisymmetric, in contrast to the case of a laterally homogeneous membrane where it is axisymmetric.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2013
    Keywords: hip joint ; pelvic shape ; pelvic parameters
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The difference between male and female femoral and pelvic geometry was studied by considering some geometrical parameters such as interhip distance, inclination of the crista iliaca, diameter of the femoral head and centre-edge angle of Wiberg. The values of these parameters were determined for 79 healthy female and 21 healthy male subjects. Standard anterior-posterior radiographs were used and processed by the computer-aided system. The results show some important sex differences in femoral and pelvic geometrical parameters which determine the hip joint contact stress.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Pflügers Archiv 431 (1996), S. R275 
    ISSN: 1432-2013
    Keywords: gait ; hip joint ; resultant hip joint force ; stress distribution ; articular surface
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The magnitude and the direction of the resultant hip joint force are different in different body positions during gait. Therefore the stress distribution in the hip joint articular surface also changes. The aim of this work is to study how the stress distribution changes if the magnitude and the direction of the hip joint force is changed during gait. For this purpose a three-dimensional mathe-matical model is developed. We calculated the values of the peak stress and the location of the pole on the articular surface (where the stress is maximal) in the successive phases of the walking cycle. The values of the peak stress range from 0.8 MPa in the one limb stance phase to 2.6 MPa in the heel strike phase.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 345-347 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this study various femoral and pelvic geometrical parameters important for hip joint contact stress were determined. The parameters were measured from standard anteroposterior radiographs of healthy adult subjects and analysed by using descriptive statistical procedures. Women proved to have a significantly smaller femoral head radius and larger distance between the inner acetabular rims than men, both features which lead to an increase of contact stress in the hip joint articular surface. Since too high, long-lasting contact stress is unfavourable regarding the development of arthrosis, we propose that these differences in the femoral and pelvic geometry could be one of the reasons for the increased incidence of arthrosis in women.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 114 (1995), S. 76-78 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A mathematical model was used in order to evaluate the mechanical situation after lateral, medial, distal and proximal displacements of the greater trochanter. It was calculated that lateral displacement may considerably reduce the hip joint contact force, while medial displacement greatly increases it. The influence of proximalization and distalization is much less pronounced. It was further shown that, regarding the postoperative relative hip abductor muscle strength, lateral and distal displacements of the greater trochanter are favourable, while proximal and medial displacements are not.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of orthopaedic and trauma surgery 116 (1997), S. 345-347 
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In this study various femoral and pelvic geometrical parameters important for hip joint contact stress were determined. The parameters were measured from standard anteroposterior radiographs of healthy adult subjects and analysed by using descriptive statistical procedures. Women proved to have a significantly smaller femoral head radius and larger distance between the inner acetabular rims than men, both features which lead to an increase of contact stress in the hip joint articular surface. Since too high, long-lasting contact stress is unfavourable regarding the development of arthrosis, we propose that these differences in the femoral and pelvic geometry could be one of the reasons for the increased incidence of arthrosis in women.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    The European physical journal 10 (1999), S. 5-8 
    ISSN: 1434-6036
    Keywords: PACS. 05.70.Np Interface and surface thermodynamics - 87.16.Dg Membranes, bilayers and vesicles
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract: Phospholipid membrane forming a closed surface and decorated with anisotropic inclusions is considered. The inclusions are free to redistribute laterally over the membrane and to orient in the plane of the membrane according to the local membrane curvature. A phenomenological expression for the energy of the interaction between an inclusion and local curvature of the surrounding membrane is proposed. Considering this single-inclusion energy, and assuming thermodynamic equilibrium, the free energy of the inclusions, and the consistently related lateral and orientational distributions of the inclusions are obtained using statistical mechanical methods. For a vesicle shape with given surface area, enclosed volume, and total amount of inclusions, the free energy is in general given in a nonlocal form (i.e. it can not be expressed as an integral of its area density over the membrane area). The limits of weak and strong orientational ordering are considered. Specifically, it is shown that in the shape sequence representing the formation of an exovesicle the effect of the membrane curvature on the orientation of the inclusions may stabilize the shape where the exovesicle and the cell are connected by a narrow neck.
    Type of Medium: Electronic Resource
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