ISSN:
0006-3525
Keywords:
Chemistry
;
Polymer and Materials Science
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The interaction of adenylyl (3′ → 5′) adenosine (ApA) with polyuridylic acid in D2O solution at neutral pD has been studied by high resolution proton magnetic, resonance spectroscopy. At temperatures above ∼32°C, no evidence was obtained for the interaction of ApA with poly U. Below this temperature, a rigid triple-stranded complex involving a stoichiometry of 1 adenine to 2 uracil bases is formed, presumably via specific adenine-uracil base-pairing and cooperative base stacking of the adenine bases in a manner similar to that previously reported for the adenosine-poly U complex.
Additional Material:
10 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/bip.360100112
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