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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 3 (1994), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 6 (1996), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 3 (1994), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 13 (1999), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Vitiligo is a common disease of unknown cause that produces disfiguring white patches of depigmentation. Previous studies have suggested the effectiveness of UV-B radiation in generalized vitiligo (GV) therapy, but there was no evidence to support the same role for segmental vitiligo (SV).〈section xml:id="abs1-3"〉〈title type="main"〉ObjectiveThe purpose of this study was to use UV-B radiation exclusively on vitiligo patches of individuals affected by S V to evaluate the effectiveness of this therapy.〈section xml:id="abs1-4"〉〈title type="main"〉Subjects and methodsEight individuals with SV were treated for 6 months with a new device called BIOSKIN® that can produce a focused beam of UV-B (microphoto-therapy) on vitiligo patches only. Photographs of the subjects were taken at the beginning of the therapy and once a month thereafter for 6 months. The response to treatment was estimated in two comparable photographs using planimetry. A control group of eight individuals matched for sex and age was treated with placebo, using the same device but not releasing any kind of detectable light.〈section xml:id="abs1-5"〉〈title type="main"〉ResultsAfter 6 months of microphototherapy five subjects of the eight studied achieved normal pigmentation on more than 75% of the treated areas. In particular, three of these were totally repigmented. Two individuals achieved 50–75% pigmentation of the treated areas, and only one showed less than 50% repigmentation (Table 3). In the control group only one patient showed moderate repigmentation (less than 50%) (Table 3) (Fig. 3).〈section xml:id="abs1-6"〉〈title type="main"〉ConclusionUV-B microphototherapy seems highly effective in restoring pigmentation in patients affected by vitiligo. As no side-effects have been observed, this could represent the treatment of choice in the limited (segmental) forms of vitiligo.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 2 (1993), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Cell adhesion molecules (CAMs) are cell surface glycoproteins expressed on several different cell lineages and involved in cell-cell and cell-matrix interactions in various physiological and pathological conditions.Numerous studies have shown that CAMs, a very substantial class of molecules subdivided into four families (integrins. the immunoglobulin-gene family, cudherins and lectin-like CAMs). are involved in the interaction of lymphocytes with keratinocytes, endothelial ceils and inter-and perivascular connective cells.Researchers have found a marked increase in the expression of CAMs with respect to normal skin in a variety of dermatoses, such as cutaneous necrotizing vasculitis. capillarities from unknown origin (purpura pigmentosa chronica). alopecia areata, lichen planus, systemic selerosis, psoriasis, etc. In the inflammatory and neoplastic skin diseases considered in this review, the adhesion molecules found to be chiefly expressed are ELAM-1, ICAM-I and LFA-I. This suggests that, predominantly, these adhesion molecules participate in the complex pathogenetic mechanisms conditioning the onset and development of these diseases. Knowledge of interaction mechanisms has led to identification of the role played by CAMs in the pathogenesis of these diseases and may represent a useful aid in the diagnosis and perhaps treatment of numerous skin pathologies.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 17 (2003), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 14 (2000), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 9 (1997), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: General description The mycobacteria are a large genus which includes important pathogens of man and other vertebrates, apparently harmless commensals, and free-living saprophytes. The relative importance of non-tuberculous mycobacterial diseases has been undergoing evolution during the past few years and further changes and modifications are expected to occur in the near future. In this paper we review the microbiological, clinical, histological and therapeutical aspects of the most important human pathogens of non–tuberculous mycobacteria.Learning objective At the conclusion of this learning activity, participants should be able to describe the pathogenesis. the microbiological, clinical and histological features of non-tuberculous mycobacterial skin infections and should be able to diagnose and treat these skin diseases.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 7 (1996), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Purpuras include a wide spectrum of cutaneous disorders characterized by extravasation of red blood cells into the skin with consequent release of hemoglobin. Various other pigments deriving from heme are subsequently found into the skin within 2-3 weeks, accounting for the color changes (purple, orange, brown, yellowish, green-blue) which may occur in most purpuric lesions. Too often the factors leading to these disturbances are obscure. Sometimes they are obscure mainly to the dermato-venereologist as they are generally considered more pertinent to the field of interest of other specialists, i.e. in hematology or internal medicine. The dermato-venereologist should be familiar with these cutaneous conditions and, when necessary, cooperate with the hematologist in order to evaluate the cutaneous and extracutaneous signs and symptoms and to schedule the proper systemic and/or topical therapies.Learning objective At the conclusion of this learning activity, participants should be able to discuss the clinical and histological presentations of purpuric disorders and know which tests should be done to allow proper diagnosis and treatment. The participants should also be aware of the controversies concerning the pathogenesis of some kinds of purpuras (i.e. palpable purpuras), of the evolution of terminology and finally of the different therapeutic options and regimens.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 1 (1992), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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