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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 11 (1982), S. 25-31 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract Uptake and depuration kinetics for benzo(a)pyrene (B(a)P) were determined for the midgeChironomus riparius (Diptera) with one and two compartment models. Nonfeeding animals were exposed to nominal 1.0μg·L−1 14CB(a)P for eight hr. Depuration over eight hr was determined in animals with and without substrate. The uptake rate constant was 214+-20 hr−1 (X+-SE, n=3), while elimination rate constants for the first four hr were 0.22 hr−1 (with substrate) and 0.06 hr−1 (without substrate). Biphasic depuration was observed with an initial rapid phase that lasted several hr. Approximately 10% of accumulated14C was associated with exoskeleton. As much as 50% of the accumulated B(a)P was transformed into polar compounds after one hr. Based on steady state14C concentration, an apparent bioconcentration factor of 650 was determined. The bioconcentration value based on B(a)P analysis was 200.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Copenhagen : International Union of Crystallography (IUCr)
    Acta crystallographica 34 (1978), S. 3411-3414 
    ISSN: 1600-5740
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Archives of environmental contamination and toxicology 38 (2000), S. 163-168 
    ISSN: 1432-0703
    Source: Springer Online Journal Archives 1860-2000
    Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine
    Notes: Abstract. Uptake, biotransformation, and elimination rates for DDE and 2-chlorobiphenyl (2-CB) were examined using fourth instar midge larvae (Chironomus tentans) under a water-only exposure. A two-compartment model that included biotransformation described the kinetics for 2-CB and a one-compartment model was used for DDE. The uptake clearance coefficient (ku) was 65.96 ± 2.09 ml · g−1 midge · h−1 for 2-CB and 84.1 ± 2.7 ml · g−1 midge · h−1 for DDE. DDE demonstrated no measurable elimination, while 2-CB showed elimination with faster elimination of parent compound (kep = 0.100 ± 0.008 h−1) compared to the polar metabolites (kem = 0.073 ± 0.016 h−1). The biotransformation rate for 2-CB (km = 0.031 ± 0.005 h−1) appeared to be time-dependent with faster rates at the beginning of the accumulation process slowing to a constant once the midge was loaded with chemical. Experimental results indicate a difference in the ability of C. tentans to eliminate 2-CB and its metabolites more quickly than DDE, and these differences were related to the bioconcentration potential of the compounds.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-5141
    Keywords: sediments ; contamination ; Great Lakes ; ARCS ; toxicity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract In response to a mandate in Section 118(c)(3) of the Water Quality Act of 1987, a program called Assessment and Remediation of Contaminated Sediments (ARCS) was established. Four technical work groups were formed. This paper details the research strategy of the Toxicity-Chemistry Work Group. The Work Group's general objectives are to develop survey methods and to map the degree of contamination and toxicity in bottom sediments at three study areas, which will serve as guidance for future surveys at other locations. A related objective is to use the data base that will be generated to calculate sediment quality concentrations by several methods. The information needed to achieve these goals will be collected in a series of field surveys at three areas: Saginaw Bay (MI), Grand Calumet River (IN), and Buffalo River (NY). Assessments of the extent of contamination and potential adverse effects of contaminants in sediment at each of these locations will be conducted by collecting samples for physical characterization, toxicity testing, mutagenicity testing, chemical analyses, and fish bioaccumulation assays. Fish populations will be assessed for tumors and external abnormalities, and benthic community structure will be analyzed. A mapping approach will use low-cost indicator parameters at a large number of stations, and will extrapolate by correlation from traditional chemical and biological studies at a smaller number of locations. Sediment toxicity testing includes elutriate, pore water and whole sediment bioassays in a three-tiered framework. In addition to the regular series of toxicity tests at primary mater stations, some stations are selected for a more extensive suite of tests.
    Type of Medium: Electronic Resource
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