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Environmental risk factors for allergy and socioeconomic status in a birth cohort (BAMSE) (2002)

Lannerö, E. ; Kull, I. ; Wickman, M. ; [et al.]

Copenhagen, Denmark : Munksgaard International Publishers

Pediatric allergy and immunology 13 (2002), S. 0

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ISSN: 1399-3038

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Associations between parental educational level and possible risk factors for atopic disease during the first months of life were explored in a cohort of 4089 neonate children born 1994–96 in Stockholm, Sweden. Reports concerning a number of life style factors during pregnancy and after the baby was born were obtained by questionnaire. There was a strong negative association between duration of education and maternal smoking during pregnancy, parental smoking after the baby was born and keeping of cat and dog (p-trend 〈 0.001), respectively. For example, smoking during pregnancy was reported by 6.7% (95% CI 5.5–7.9) of mothers with college or university degree and by 22.2% (95% CI 20.1–24.5) of those with the shortest education. Indicators of dampness and poor ventilation were also more common in homes of those with the shortest education. The results show that the educational level has an influence on risk factors for development of atopic disease in childhood and indicates a need of deeper understanding of life style in different socioeconomic groups. The data also indicate that various possible confounding factors need to be thoroughly investigated when analysing studies of risk factors for allergic disease in childhood.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1034/j.1399-3038.2002.01055.x

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A pilot study of lead and cadmium exposure in young children in Stockholm, Sweden: Methodological considerations using capillary blood microsampling (1994)

Berglund, M. ; Lind, B. ; Lannerö, E. ; [et al.]

Springer

Archives of environmental contamination and toxicology 27 (1994), S. 281-287

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ISSN: 1432-0703

Source: Springer Online Journal Archives 1860-2000

Topics: Energy, Environment Protection, Nuclear Power Engineering , Medicine

Notes: Abstract A capillary blood microsampling technique was tested among urban young children in Stockholm. Blood lead (BPb) and hemoglobin (Hb) concentrations were determined in capillary blood obtained by fingerstick from 41 children, 13–20 months old, and the accompanying parent. The quality control included control for lead (Pb) and cadmium (Cd) contamination of material and equipment used for blood sampling, washing procedures for the hands and fingers to be punctured, comparisons of Pb and Cd concentrations in blood obtained by fingerstick and by brachial vein puncture from the same individuals, analysis of external quality control samples for Pb and Cd in blood together with the collected samples, and evaluation of the analytical performance using linear regression analysis. The results showed that blood sampling material may contaminate the blood samples with amounts of Pb and Cd that would seriously influence the monitoring results in the low concentration range (〈100 μg Pb/L and 〈1 μg Cd/L). However, it is possible to obtain reliable BPb concentrations (〉10 μg Pb/L), but not BCd concentrations (〈1 μg Cd/L), with the capillary blood microsampling technique tested provided that a strict quality control is applied. The sampling procedure tested was well accepted by the children and their parents. The children's median BPb concentration (27 μg/L; range 9–73 μg/L) was similar to the median BPb concentration of their parents (27 μg/L; range 7–74 μg/L). However, the correlation between child and parent BPb concentrations was poor (R2=0.20), which may indicate different sources to Pb exposure in children and parents.