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Premature Birth induced in Mice by Salicylate (1968)

ERIKSSON, M. ; LARSSON, K. S.

[s.l.] : Nature Publishing Group

Nature 220 (1968), S. 385-385

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ISSN: 1476-4687

Source: Nature Archives 1869 - 2009

Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics

Notes: [Auszug] Sixty-one pregnant primiparous A/Jax mice were used. plug was observed was denoted as the zero day of pregnancy. On the seventeenth day of gestation, at 1000 h, the mothers were given a single intramuscular injection of 0-1 ml. per 20 g body-weight of the appropriate solutions (Table 1), while the ...

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1038/220385a0

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Electrical impedance — a new parameter for oral mucosal irritation tests (1992)

Nilsson, R. ; Fallan, J. O. ; Larsson, K. S. ; [et al.]

Springer

Journal of materials science 3 (1992), S. 278-282

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ISSN: 1573-4838

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine , Technology

Notes: Abstract The potential for dental materials to irritate human oral mucosal membranes was assessed by an electrical impedance technique. A small electrode at the site of irritation on the inside of the cheek and a large electrode on the outside of the cheek were used. Skin impedance was reduced by inundation with ECG-gel. An irritation index was formed by calculating the quotient between the impedance absolute value at 20 kHz and the impedance value at 1 MHz. Electrical impedance technology was found to be more sensitive than traditional visual registration of mucosal reactions. Two series of experiments were performed in which special appliances were constructed to ensure duplicate measurements on the small area of exposed buccal mucosa. Liquid samples elicited differentiated fast response, which was insignificantly influenced by mechanical factors. The mechanical irritation induced by merely the shape of a solid specimen prevents detection of slight mucosal irritation from potentially leaking substances.