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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Inflammation research 7 (1977), S. 199-202 
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The effects of histamine (10−7–10−5 M) on the cardiac action potential have been studied in ventricular strips of guinea pig heart, electrically driven at a constant rate. A decrease of action potential was constantly observed at histamine concentrations above 10−6 M. No significant variations of the other electrophysiological parameters were induced by the amine. The decrease in the duration of the action potential was blocked by burimamide at a concentration (10−4 M) which induced only slight changes in action potential outline. It is suggested that the shortening of the repolarization phase induced by histamine is due to the H2 receptor-mediated activation of the calcium inward current, which can increase the intracellular calcium concentration influencing the potassium permeability.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-908X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The positive inotropic effects of 2-pyridyl-ethylamine (PEA) and of 4-methylhistamine (4MeH) were studied in isolated guinea-pig ventricular strips electrically stimulated at a rate of 60 and 150/min. The increase in contractile tension induced by PEA (10−7−3×10−4 M) in the presence of cimetidine (10−5 M) was associated with a slight increase in time to peak tension and with a lengthening of the relaxation phase; the positive inotropic effect of PEA was significantly higher at a frequency of 60/min than at 150/min. Conversely, the inotropic response to 4MeH (10−8−3×10−6 M)was not frequency dependent, and was associated with an evident decrease in relaxation time. Moreover, 4MeH consistently antagonized, in dosedependent manner, the negative inotropic effects induced by the calcium antagonistic drug D600 and by lowering calcium concentration in the medium, and was able to restore the contractility abolished by treatment of preparations with a high K+ medium. On the other hand PEA, in the presence of cimetidine, scarcely antagonized the negative inotropic effects induced either by D600 or by low calcium solution, and was unable to restore the contractility of K+-depolarized preparations. The characteristics of the inotropic response of the H1-receptor agonist were very similar to those of the alpha-adrenoceptor agonist phenylephrine. This observation suggests that a common mechanism is probably involved in the inotropic effects mediated by H1 and by alpha receptors, and that this mechanism does not include a stimulation of the calcium transmembrane influx.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1440
    Keywords: Mushroom poisoning ; Diagnosis and therapy ; Chronic active hepatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary One hundred and sixty cases of mushroom poisoning during the period July–November 1981 are reported. The survey details 116 observations of short incubation syndromes and 44 cases of delayed syndrome, identified asAmanita Phalloides poisoning. Of the latter, 40 patients were adult (mean age 46 years, range 20–77; 18 females and 22 males) and 4 were children (≤ 12 years old; 3 females and 1 male). All the patients withAmanita Phalloides poisoning were treated according to a therapeutic protocol, based on the infusion of high doses of penicillin G, administration of dexamethasone and thioctic acid, careful correction of water and electrolyte unbalance. The severity of the disease varied in the population of 44 patients: 4 patients died (2 females, 10 and 77 years old; 2 males, 56 and 64 years old); 26 patients were discharged from the hospital as clinically cured; 14 were discharged with persistently abnormal levels of transaminases and they were advised of a follow-up evaluation. The average length of stay in hospital was 2 weeks. Of the patients followed-up, 6 were symptom-free after 6 months, with normal transaminase values and a normal histopathological picture of liver biopsy specimens. In the remaining patients, there was no normalization of transaminase values and liver biopsy specimens showed a picture of chronic active hepatitis. These patients displayed abnormal immunological tests, with presence of immune complexes and of anti-smooth muscle autoantibodies. The results indicate thatAmanita Phalloides poisoning represents a threat not only in the high mortality acute phase, but also in the development of chronic active hepatitis in some survivors.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1440
    Keywords: Alcoholic disease ; Biological markers ; Therapeutic protocols
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The early diagnosis and evaluation of the biological consequences of alcohol abuse are reviewed in a population of 401 chronic alcoholics admitted to our Toxicological Unit from January 1973 to the end of December 1984; selected cases were treated with disulfiram implantation. The results of the study indicate that anemia with increased globular volume of erythrocytes, elevated serum γ-glutamyl-transferase activity, increased postprandial cholalemia, and increased elimination of pentane in the breath can be considered suitable markers for the early diagnosis of alcohol abuse. Disulfiram implantation significantly prolonged the abstinence duration in the treated patients.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 1674-1680 
    ISSN: 0392-6737
    Keywords: Methods of crystal growth and purification
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Si riportano i risultati di un'indagine sistematica condotta su soluzioni solide ottenute da fasi tetraedriche quaternarie a composizione generale AIB2 IICIIITe4. Sono stati esaminati i seguenti sistemi:a) Cu x Ag1−x Cd2InTe4, CuCd2xZn2(1−x)InTe4, CuCd2In x Ga1−x Te4 eb) Cu x Ag1−x Zn2x Cd2(1−x)Ga x In1−x Te4, ottenuti rispettivamente per singola e tripla sostituzione degli atomi nei siti cationici e caratterizzati attraverso analisi microscopiche termodifferenziali e röntgenografiche. Tutti i campioni si comportano come semiconduttori di tipop. La possibilità di modificare il segno e la densità dei portatori di carica è stata verificata sperimentalmente operando piccole variazioni nel rapporto stechiometrico dei cationi. Si riportano inoltre i risultati delle misure sulle proprietà fondamentali di transporto effettuate sul sistema Cu x Ag1−x Cd2InTe4.
    Abstract: Резюме Сообщаются результаты систематического исследования твердых растворов AIB2 IICIIITe4. Исследуются следующие системы:a) Cu x Ag1−x Cd2InTe4, CuCd2x Zn2(1−x)InTe4, CuCd2In x Ga1−x Te4 иb) Cu x Ag1−x Zn2x Cd2(1−x)Ga x In1−x Te4, полученные с помщшью однократного и трехкратного замещений в узлах катионов. Как следует из рентгеновского, DTA и микроскопического анализа все образцы представляют единственную фазу с кубической сфалеритической структурой. Исследо-ванные образцы ведут себя как полупроводникиp-типа. Эксперименталчно проверена возможность изменения знака и плотности носителей эа счет изменения стехиометрического отношения катионов. Приводятся резулчтаты для основных транспортных свойств системы Cu x Ag1−x Cd2Te4.
    Notes: Summary The results of a systematic investigation on solid solutions derived from quaternary tetrahedral phases of AIB2 IICIIITe4 composition are reported. The following systems:a) Cu x Ag1−x Cd2InTe4, CuCd2x Zn2(1−x)InTe4, CuCd2In x Ga1−x Te4 andb) Cu x Ag1−x Zn2x Cd2(1−x)Ga x In1−x Te4, obtained by single (a)) and threefold (b)) substitutions at cation sites have been examined. As determined by X-ray, DTA and microscopic analysis, all samples appear to be single-phased with a cubic sphalerite structure. The examined samples behave asp-type semiconductors. The possibility of changing the sign and the density of carriers, by varying the stoichiometric ratio of the cations, has been experimentally verified. The results on the main transport properties for the Cu x Ag1−x Cd2Te4 system are reported.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Il nuovo cimento della Società Italiana di Fisica 2 (1983), S. 1995-2001 
    ISSN: 0392-6737
    Keywords: Photoconduction and photovoltaic effects ; photodielectric effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Description / Table of Contents: Riassunto Sono state misurate le caratteristiche fotoelettriche piú significative dei composti appartenenti al sistema Cu x Ag1−x Cd2InTe4. Dalla dipendenza spettrale della fotoconducibilità misurata a temperatura ambiente ed a 77K, sono stati dedotti i valori dell'energia del gap ed i loro coefficienti termici. Le misure effettuate hanno anche permesso la determinazione dei valori della detettivitàD *, del guadagnoG, del tempo di vita e della mobilità dei portatori. In conclusione si effettua un'analisi dei parametri che regolano laD * al fine di migliorare le caratteristiche di questi composti come fotorivelatori.
    Abstract: Резюме Приводятся основные фотоэлектрические параметры для полупроводящих твердых растворов Cu x Ag1−x Cd2InTe4. Из спектральной зависимости фотопроводимости при комнатной температуре и при 77 К получаются значения энергетических щелей и их температурные коэффициенты. Измеряются вьшрямлениеD *, усиление фототокаG и время жизни носителей. Определяется подвижность носителей. Для улучшения характеристикиD * проводится анализ этих параметров.
    Notes: Summary The prominent photoelectric parameters of the semiconducting solid solutions Cu x Ag1−x Cd2InTe4 are reported. From the spectral dependence of photoconductivity at room temperature and at 77 K the energy gaps and their thermal coefficients are obtained. The detectivityD *, the photocurrent gainG and the carrier lifetime are measured and the carrier mobility is deduced. In order to improve theD * characteristics, the analysis of its parameters is also performed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 192 (1993), S. 1198-1203 
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 0022-3697
    Keywords: SnSb"2Te"4 ; cation order
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Journal of Physics and Chemistry of Solids 50 (1989), S. 1195-1196 
    ISSN: 0022-3697
    Keywords: Mossbauer spectra ; Sb-Te alloys
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
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