ISSN:
1612-1112
Keywords:
Column liquid chromatography
;
Phthalic anhydride
;
Naphthoquinones
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Summary A simple method of analysis of the 1,2 and 1,4 isomers of naphthoquinone in crude phthalic anhydride has been developed. The sample was first dissolved in water at 60°C to quantitatively hydrolyse the anhydride to phthalic acid. Analysis of the aqueous solution by reversed-phase HPLC using 75∶25 methanol:water mobile phase resulted in excellent resolution between the phthalic acid and the naphthoquinones and enabled quantitative measurement of each of the naphthoquinones to 0.1 % in crude phthalic anhydride.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02280604
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