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  • 1
    Electronic Resource
    Electronic Resource
    Downstream boundary effects on the spectral characteristics of a swirling flowfield (1991)
    Springer
    Experiments in fluids 10 (1991), S. 341-348 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The spectral characteristics and the structural response of a swirling flowfield are investigated subject to a non-axisymmetric disturbance and a contraction imposed downstream. Two natural frequencies are noted in different regions of the undisturbed swirling flowfield, one is due to a precessing vortex core and the other to the most amplified downstream azimuthal instability. The downstream contraction usually causes compression of the central recirculation zone into two side-lobes, increases the dominant frequencies and forms a straight central vortex core with a high axial velocity. The dominant downstream instability frequency depends linearly on the inlet Reynolds number and on the mode of the breakdown. For the downstream non-axisymmetric disturbance, such as the passing of the turbine blades, the fundamental frequency is not altered by the disturbance and the oscillation strength of the downstream instability is greatly reduced as the excitation frequency remains unmatched with the dominant downstream natural frequency. Downstream azimuthal instability promotes the breakdown recirculation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190250
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  • 2
    Electronic Resource
    Electronic Resource
    Swirling flows in circular-to-rectangular transition ducts (1996)
    Springer
    Experiments in fluids 20 (1996), S. 401-409 
    Details
    ISSN: 1432-1114
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Swirling flows in three circular-to-rectangular transition ducts, each of them with an aspect ratio of 2.0 at the rectangular exit, have been studied experimentally. The swirling flows were produced by swirlers whose vane angles were at 5°, 10° and 20° inclinded to the incoming flow, respectively. Flow visualization experiments were made at selected cross-sectional planes in the transition ducts. Pressure and velocity measurements were obtained on the contoured duct walls and at the rectangular exit planes, respectively. The results show that the swirling flow pattern evolves into a skewed structure at the exit plane which, in connection with the wall pressure distributions, is asymmetric with respect to the centerline of either the top and bottom walls or the side walls. Moreover, an analysis based on the mean streamwise vorticity equation with the velocity data obtained immediately downstream of the rectangular exit plane indicates that the cross-stream Reynolds stress plays an important role in transporting the streamwise vorticity of the swirling flow into the surrounding fluid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00189378
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  • 3
    Electronic Resource
    Electronic Resource
    Deformed hedgehog and baryon resonances in the Skyrme model
    Amsterdam : Elsevier
    Nuclear Physics, Section A 449 (1986), S. 673-682 
    Details
    ISSN: 0375-9474
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0375-9474(86)90327-1
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  • 4
    Electronic Resource
    Electronic Resource
    The melanin operon of Streptomyces antibioticus: expression and use as a marker in Gram-negative bacteria
    Amsterdam : Elsevier
    Gene 86 (1990), S. 123-128 
    Details
    ISSN: 0378-1119
    Keywords: E. coli host ; Erwinia ; Recombinant DNA ; Xanthomonas ; lac promoter ; plasmid ; shuttle vector ; signal peptide
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://linkinghub.elsevier.com/retrieve/pii/0378-1119(90)90124-A
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  • 5
    Electronic Resource
    Electronic Resource
    Possible use of a polymerase chain reaction method for specific detection of Salmonella in beef
    Amsterdam : Elsevier
    Journal of Fermentation and Bioengineering 77 (1994), S. 137-143 
    Details
    ISSN: 0922-338X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0922-338X(94)90312-3
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  • 6
    Electronic Resource
    Electronic Resource
    Site of Protonation and Proton Affinity of Acrylamide. A Theoretical Study (1995)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 99 (1995), S. 1454-1461 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100005a014
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  • 7
    Electronic Resource
    Electronic Resource
    Eradication of Helicobacter pylori prevents ulcer development in patients with ulcer-like functional dyspepsia (2001)
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 15 (2001), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Although the eradication of Helicobacter pylori infection benefits patients with gastric or duodenal ulcers, the value of eradicating the infection in the patients with functional dyspepsia (FD) remains controversial.〈section xml:id="abs1-2"〉〈title type="main"〉Aims:To determine whether eradicating H. pylori can prevent the subsequent development of ulcers or relieve the symptoms of functional dyspepsia patients.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:In a double-blind, placebo-controlled trial, 161 patients infected with H. pylori who had functional dyspepsia were randomly assigned to 7 days of treatment with a lansoprazole-based triple therapy or placebo and then followed for 1 year. The main outcome measures were the development of peptic ulcers and the resolution of symptoms.〈section xml:id="abs1-4"〉〈title type="main"〉Results: H. pylori was eradicated in 63 out of 81 patients (78%) in the treatment group and none of the 80 patients (0%) in the placebo group. During the follow-up period, two patients in the treatment group and six patients in the placebo group developed peptic ulcers at repeat endoscopy (2.5% vs. 7.5%; 95% CI: –12 to 2). The reduction in ulcer rates was statistically significant in the ‘ulcer-like’ sub-group (0% vs. 16.7%; 95% CI: –32 to –2), but not in the ‘dysmotility-like’ and ‘unclassifiable’ sub-groups. Regarding symptom response, the resolution rates of symptoms were similar between the treatment and placebo groups (58.0% vs. 55.0%, 95% CI: –12 to 18). Additionally, no significant differences existed in the symptom responses between the treatment and control arms in each of the dyspepsia sub-groups.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Eradicating H. pylori can prevent the subsequent development of peptic ulcers in the patients with ‘ulcer-like’ functional dyspepsia. However, this approach does not significantly reduce the symptoms of functional dyspepsia patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2001.00903.x
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  • 8
    Electronic Resource
    Electronic Resource
    Risks of interleukin-1 genetic polymorphisms and 〈fr〉Helicobacter pylori〈/fr〉 infection in the development of gastric cancer (2004)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 20 (2004), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : The host genetic factors that determine the clinical outcomes of Helicobacter pylori-infected individuals remain unclear.Aim : To elucidate the risks of host interleukin-1 (IL-1) genetic polymorphisms and H. pylori infection in the development of gastric cancer.Methods : In a case–control study of 164 controls and 142 patients with gastric cancer, the IL-1B-511 biallelic polymorphisms and the IL-1RN penta-allelic variable number of tandem repeats were genotyped.Results : The carriage of IL-1RN*2, male gender, old age and H. pylori infection independently increased the risk of gastric cancer, with odds ratios of 3.3 [95% confidence interval (CI), 1.4–7.7], 2.1 (95% CI, 1.2–3.8), 5.3 (95% CI, 3.1–9.0) and 2.2 (95% CI, 1.3–3.8), respectively. H. pylori-infected individuals who were carriers of IL-1RN*2 showed increased risks of both intestinal and diffuse types of gastric cancer, with odds ratios of 11.0 and 8.7, respectively. In addition, these individuals also had a higher score of intestinal metaplasia in the corpus than did uninfected non-carriers.Conclusions : This study is the first to verify IL-1RN*2 as an independent factor governing the development of gastric cancer in Asian individuals. A combination of H. pylori testing and host genotyping may target the eradication of H. pylori to high-risk individuals.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2004.01826.x
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  • 9
    Electronic Resource
    Electronic Resource
    Corrosion fatigue behaviour of a 15Cr-6Ni precipitation-hardening stainless steel in different tempers (2000)
    Oxford, UK : Blackwell Science Ltd
    Fatigue & fracture of engineering materials & structures 23 (2000), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Systematic fatigue experiments, including both high-cycle axial fatigue (S–N curves) and fatigue crack growth (FCG, da/dN–ΔK curves), were performed on a precipitation-hardening martensitic stainless steel in laboratory air and 3.5 wt% NaCl solution. Specimens were prepared in three tempers, i.e. solution-annealed (SA), peak-aged (H900) and overaged (H1150) conditions, to characterize the effects of ageing treatment on the corrosion fatigue (CF) resistance. S–N results indicated that fatigue resistance in all three tempers was dramatically reduced by the aqueous sodium chloride environment. In addition, the smooth-surface specimens in H900 temper exhibited longer CF lives than the H1150 ones, while those in SA condition stood in between. However, for precracked specimens, the H1150 temper provided superior corrosive FCG resistance than the other two tempers. Comparison of the S–N and FCG curves indicated that early growth of crack-like defects and short cracks played the major role in determining the CF life for smooth surface. The differences in the CF strengths for the S–N specimens of the given three tempers were primarily due to their inherent differences in resistance to small crack growth, as they were in the air environment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1460-2695.2000.00313.x
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  • 10
    Electronic Resource
    Electronic Resource
    Overproduction of inhibitory hematopoietic cytokines by lipopolysaccharide-activated peripheral blood mononuclear cells in patients with aplastic anemia (1995)
    Springer
    Annals of hematology 71 (1995), S. 281-286 
    Details
    ISSN: 1432-0584
    Keywords: Aplastic anemia ; MIP-1α ; TNF-α ; TGF-β2 ; IFN-γ
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to measure the level of cytokines produced by peripheral blood mononuclear cells (PBMNC) in patients with aplastic anemia (AA) and to determine their effect on the clonal growth of normal bone marrow (BM) cells. Twenty-one patients with AA and 11 normal controls were enrolled in this study. Medium conditioned by PBMNC of AA patients in the presence of lipopolysaccharide (LPS) was found to be suppressive to the colony growth of normal BM cells. Thus, we further determined the presence in the PBMNC-conditioned medium (CM) of both inhibitory cytokines: macrophage inflammatory protein-1α (MIP-1α), tumor necrosis factor-α (TNF-α), transforming growth factor-β2 (TGF-β2), and interferon-γ (IFN-γ), and stimulatory cytokines: interleukin-3 (IL-3) and stem cell factor (SCF). Spontaneous production of MlP-1α was higher in the AA patients than the normal controls (1887±174 pg/ml vs 1643±93 pg/ml), but the difference was not significant. After LPS stimulation, the production of MIP-1α was markedly increased in the AA patients, and its level was significantly higher than that of the normal controls (2360±149 pg/ml vs 1517±92 pg/ml, p=0.0022). The level of TNFα was also higher in the AA patients. However, IFN-γ, TGF-β2, SCF, and IL-3 were not detectable in the PBMNC-CM of either AA patients or normals. The myelopoietic suppressing effect of AA-PBMNC-CM from each AA patient was significantly blocked by pretreatment with anti-TNF-α, resulting in a colony-forming enhancement of 174%±12%. A similar effect was noted in six of 11 AA patients by pretreatment with anti-MIP-1α. We conclude that TNFα and MIP-1α can be overproduced by the PBMNC of some AA patients, which may play a role in the progression of AA.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01697980
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