ISSN:
1089-7623
Quelle:
AIP Digital Archive
Thema:
Physik
,
Elektrotechnik, Elektronik, Nachrichtentechnik
Notizen:
The recurrent difficulties of rapidly localizing a small object in a large volume of highly scattering material such as brain and breast has been the "stumbling block'' of optical methods for tumor detection. Amplitude cancellation of in- and out-of-phase photon diffusion patterns, used in detection of small objects containing highly absorbing and fluorescing contrast agents provides real time, two- and three-dimensional localization of objects of mg size and picamole contents in models of human breast and brain tumors with positional accuracies of millimeters. A simple robust electronic circuit is described and tested to give a phase accuracy of ∼0.1°. An electro-optical scan rapidly detects small objects in a large volume that simulates the absorption/scattering characteristics of human head or breast. © 1996 American Institute of Physics.
Materialart:
Digitale Medien
URL:
http://dx.doi.org/10.1063/1.1147534
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