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  • 1
    ISSN: 1432-1238
    Keywords: Topical anaesthesia ; Lidocaine ; Upper airways ; Respiratory resistance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To assess if two different forms of upper airway topical anaesthesia induce similar changes in airway flow resistance (Rrs). Design Serial measurements of Rrs before and after topical anaesthesia with acqueous or paste lidocaine. Setting Lung function test laboratory. Participants 9 normal men with documented normal lung function tests. Interventions 2 different session of topical upper airway anaesthesia with 100 mg of liquid 5% lidocaine and 100 mg of 2% lidocaine paste, respectively. Measurements and results Rrs was measured by the random noise forced oscillation technique. Fiberoptic upper airway examination was performed in two subjects. Rrs increased on average by 81% after lidocaine spray and by 68% after lidocaine paste (p〈0.005, respectively) with no difference in the magnitude of Rrs increase between the two modes of anaesthesia studied. This increase lasted 13±3 min (spray) and 12±3 min (paste), respectively (p=ns). Fiberoptic examination of the two most responders showed inspiratory laryngeal collapse. Conclusions Topical upper airway anaesthesia transiently increases Rrs with no specific effects regarding the drug presentation. Laryngeal dysfunction may be one mechanisms involved in Rrs increase following upper airway topical anaesthesia. Such findings may explain some poor respiratory tolerance reported during endoscopy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 18 (1980), S. 291-298 
    ISSN: 1741-0444
    Keywords: Digital computer ; Plethysmograph ; Pulmonary volumes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The actual gas contents of lungs can be measured by a total plethysmographic technique. A classical way of obtaining thoracic gas volume (t.g.v.) is by fitting a straight line to the thoracic volume (Vt) and mouth pressure (Pm) changes occurring during a panting manoeuvre with airway occlusion at the mouth. In our lung-function laboratory, a minicomputer has been connected to a pressure-compensated flow body plethysmograph. We describe here both the plethysmographic technique of measuring thoracic flow (V′t) and the computerised system developed to calculate on-line lung volumes in patients. By replacing Vt and Pm by their time derivatives, V′t and P′m, in the linear regression procedure, we significantly improve the correlation coefficient, namely the confidence which can be attributed to calculated t.g.v. The within-subject reproducibility of lung volumes is thus improved, and a closer comparison is found between the computer-derived and hand-calculated volumes, both in normal subjects and patients.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Medical & biological engineering & computing 24 (1986), S. 541-544 
    ISSN: 1741-0444
    Keywords: Forced random noise ; FFT ; Lung-function laboratory ; Microcomputer ; Respiratory impedance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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