ISSN:
1434-9949
Keywords:
Interferon
;
Synovitis
;
Auto-Immune Disease
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary From these data it appears that IFN is capable of stimulating prostaglandin E and hyaluronic acid production by human synovial fibroblastsin vitro and of initiating an inflammatory reaction in animal joints. In chronic arthritis its production may result from persisting viral or other antigenic stimulation. IFN may enhance the immune response and mediate the inflammatory process in the joint. Its role in the pathogenesis of rheumatic and various other autoimmune diseases is undergoing further study.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF02032343
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