ISSN:
1432-2161
Keywords:
Key words Etidronate
;
Osteomalacia
;
Paget’s disease
;
Vertebral collapse
;
X-rays
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract Inhibition of skeletal mineralisation is a well-recognized complication of disodium etidronate therapy that was identified in the earliest studies of its use in osteoporosis and Paget’s disease. The effect is seen at lower doses in Paget’s disease than in osteoporosis. Several cases of spontaneous fractures occurring in unaffected bones of Paget’s patients have been reported. However, we believe the case described here is the most severe example of etidronate-induced osteomalacia published in the literature, featuring widespread vertebral collapse occurring as a consequence of nearly 10 years of uninterrupted etidronate treatment for isolated hemipelvic Paget’s disease.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s002560050608
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