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Fusion Neutronic Source deuterium–tritium neutron spectrum measurements using natural diamond detectors (1997)

Krasilnikov, A. V. ; Kaneko, J. ; Isobe, M. ; [et al.]

[S.l.] : American Institute of Physics (AIP)

Review of Scientific Instruments 68 (1997), S. 1720-1724

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ISSN: 1089-7623

Source: AIP Digital Archive

Topics: Physics , Electrical Engineering, Measurement and Control Technology

Notes: Two natural diamond detectors (NDDs) operating at room temperature were used for Fusion Neutronics Source (FNS) deuterium–tritium (DT) neutron spectra measurements at different points around the tritium target and for different deuteron beam energies. Energy resolution of both NDDs were measured, with values 1.95% and 2.8%. Due to the higher energy resolution of one of the two NDDs studied it was possible to measure the shape of the DT neutron energy distribution and its broadening due to deuteron scattering inside the target. The influence of pulse pileup on the energy resolution of the combined system (NDD+electronics) at count rates up to 3.8×105 counts/s was investigated. A 3.58% energy resolution for the spectrometric system based on NDD and a 0.25 μs shaping time amplifier has been measured at a count rate of 5.7×105 counts/s. It is shown that special development of a fast pulse signal processor is necessary for NDD based spectrometry at count rates of approximately 106 counts/s. © 1997 American Institute of Physics.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1063/1.1148001

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Intracerebroventricular Administration of Melanin-Concentrating Hormone Suppresses Pulsatile Luteinizing Hormone Release in the Female Rat (2000)

Tsukamura, H. ; Thompson, R. C. ; Tsukahara, S. ; [et al.]

Oxford, UK : Blackwell Science Ltd

Journal of neuroendocrinology 12 (2000), S. 0

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ISSN: 1365-2826

Source: Blackwell Publishing Journal Backfiles 1879-2005

Topics: Medicine

Notes: Melanin-concentrating hormone (MCH) has been reported to be involved in the regulation of feeding behaviour in rats and mice. Because many neuropeptides that influence ingestive behaviour also regulate reproductive function, the present study was designed to determine if central administration of MCH changes pulsatile secretion of luteinizing hormone (LH) in the rats. Wistar-Imamichi strain female rats were ovariectomized and implanted with oestradiol to produce a moderate inhibitory feedback effect on LH release. The effects of i.c.v. injections of MCH on LH release were examined in freely moving animals. Blood samples were collected every 6 min for 3 h through an indwelling cannula. After 1 h of sampling, MCH (0.1, 1 or 10 μg/animal) or vehicle (saline) was injected into the third cerebroventricle. Because MCH is also reported to affect the hypothalamo-pituitary-adrenal (HPA) axis, which in turn, can influence reproductive function, plasma corticosterone concentrations were determined in the same animals at 30-min intervals during the first and last hours and every 12 min during the second hour of the 3-h sampling period. When expressed as per cent changes, mean plasma LH concentrations after MCH administration were significantly lower in the animals injected with all doses of the peptide compared with vehicle-treated animals; LH pulse frequency was significantly lowered by 1 μg of MCH. Per cent changes in mean plasma corticosterone levels were not significantly affected by MCH administration. These results in oestradiol-treated ovariectomized rats indicate that central MCH is capable of inhibiting pulsatile LH secretion. We have previously shown that 48-h fasting suppresses pulsatile LH release in the presence of oestrogen. Take together, these results raise the possibility that MCH could play a role in mediating the suppression of LH secretion during periods of reduced nutrition.