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  • 1
    Electronic Resource
    Electronic Resource
    Pituitary adenomas secreting more than two hormones (1979)
    Springer
    Acta neuropathologica 48 (1979), S. 67-72 
    Details
    ISSN: 1432-0533
    Keywords: Pituitary adenoma ; Ultrastructure ; Classitication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of pituitary adenoma secreting more than two hormones is presented. Morphological findings of this tumor have been correlated with biological behavior and with hormonal activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691794
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  • 2
    Electronic Resource
    Electronic Resource
    Scanning electron microscopy (S.E.M.) of biopsy specimens of ruptured intracranial saccular aneurysms (1978)
    Springer
    Acta neuropathologica 44 (1978), S. 131-134 
    Details
    ISSN: 1432-0533
    Keywords: Scanning electron microscopy ; Intracranial aneurysms ; Biopsy specimens ; Endothelial changes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Surgical specimens of 4 intracranial saccular aneurysms were studied by scanning electron microscopy. The internal surface of the aneurysms showed crater-like defects and cytoplasmic bridges. In some areas the endothelium was preserved, but its longitudinal convolutions were higher and thicker than those found in unchanged areas. On the damaged endothelial surface there was an increased number of blood cells. The adventitia resembled that of a normal cerebral artery. In conclusion the alterations observed are similar to those found in atherosclerosis and are most likely dut to the high wear and tear provoked by the blood streaming into the aneurysm. The results of this study are in agreement with the findings of a companion transmission electron microscopy study and emphasize the importance of degenerative changes on the development and rupture of intracranial saccular aneurysms.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00691478
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Fine structure of prolactin pituitary adenoma with special reference to annulate lamellae (1979)
    Springer
    Acta neuropathologica 46 (1979), S. 163-166 
    Details
    ISSN: 1432-0533
    Keywords: Electron microscopy ; Pituitary adenoma ; Annulate lamellae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Electron microscopy revealed the presence of annulate lamellae in the cytoplasm of a heavily granulated prolactin cell adenoma that had been removed from a 34-year-old male patient presenting impotence. To our knowledge this is the third case of pituitary adenomas where annulate lamellae are reported.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00684820
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Histological and ultrastructural study of intracranial saccular aneurysmal wall (1978)
    Springer
    Acta neurochirurgica 43 (1978), S. 171-182 
    Details
    ISSN: 0942-0940
    Keywords: Aneurysms ; electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The material studied consists of 10 cases of intracranial saccular aneurysms. Four came from autopsies, and in each of the other six aneurysmal wall was obtained at surgery after clipping of the aneurysm. The most significant findings from this pathological study are the almost complete disappearance of the internal elastic lamina at the level of the aneurysmal neck, sclerosis of the muscle coat, and in satellite vessels and vasa vasorum disruption of the internal elastic lamina and partial luminal occlusion. The importance of ischaemic changes in the aneurysmal wall is discussed. Rupture of the aneurysm at the distal extremity of the sac depends probably on the progressive brittleness of its wall which becomes sclerotic and less resistant to the blood pressure within. Splitting or rupture of the aneurysm appears to be dependent on degenerative ischaemic alterations in its wall.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01587953
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Pituitary abscesses: Report of two cases and review of the literature (1980)
    Springer
    Acta neurochirurgica 51 (1980), S. 209-217 
    Details
    ISSN: 0942-0940
    Keywords: Pituitary abscess ; brain abscess ; pituitary tumour ; infection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two cases of pituitary abscess are reported. Bacteriological and histological findings of both cases are discussed, together with data available from the literature.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01406747
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  • 6
    Electronic Resource
    Electronic Resource
    Proceedings of the joint meeting of the society of british neurological surgeons and the società italiana di neurochirurgia, Venice, May 15–17, 1980 (1981)
    Springer
    Acta neurochirurgica 57 (1981), S. 129-147 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01665124
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  • 7
    Electronic Resource
    Electronic Resource
    Malignant astrocytoma associated with arteriovenous malformation (1979)
    Springer
    Acta neurochirurgica 50 (1979), S. 305-309 
    Details
    ISSN: 0942-0940
    Keywords: Brain mixed tumour ; malignant astrocytoma ; vascular malformation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The coincidence of vascular malformation and primary brain neoplasm is very rare. A prevalently venous malformation associated with a malignant astrocytoma of the left temporal lobe is reported, and the pathological features are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01808529
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Pituitary microadenomas: Surgical results and morphological findings (1983)
    Springer
    Acta neurochirurgica 69 (1983), S. 231-242 
    Details
    ISSN: 0942-0940
    Keywords: Pituitary microadenoma ; transsphenoidal approach ; endocrine outcome ; electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The results of transsphenoidal microsurgery in treating 22 patients with pituitary microadenomas are reported. Histological and ultrastructural comparative studies were performed in attempting to obtain a more accurate morphological classification of pituitary microadenomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401810
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    Paper (German National Licenses)
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  • 9
    Electronic Resource
    Electronic Resource
    Immune infiltrates and cytokines in gliomas (1996)
    Springer
    Acta neurochirurgica 138 (1996), S. 50-56 
    Details
    ISSN: 0942-0940
    Keywords: Glioma ; macrophages ; cytokines
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Frozen sections of 21 gliomas were analysed to characterize inflammatory infiltrating cells, HLA-DR antigen expression and cytokine secretion. Mononuclear cells infiltrating the tumours were mostly macrophages, which were detected in 100% of cases, and expressed HLA-DR antigens. Lymphocytes were less frequently seen and expressed the CD8 phenotype. Interleukin-1 beta (IL-1β) and Interleukin-6 (IL-6), two cytokines mainly produced by activated cells of the macrophage lineage, were demonstrated expecially in neoplastic astrocytes. IL-1β immunoreactivity was detected in all tumours, and was prevalent in more anaplastic gliomas; IL-6 was found in anaplastic gliomas and in glioblastomas. IL-1 receptors were expressed by both infiltrating macrophages and neoplastic astrocytes in the gliomas analysed. These findings suggest that cytokine production in gliomas seems not related to immune reactions against the tumour and their synthesis by anaplastic astrocytes could follow an unregulated activation of many metabolic processes after neoplastic transformation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01411724
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Subarachnoid haemorrhage of unknown aetiology (1979)
    Springer
    Acta neurochirurgica 48 (1979), S. 217-221 
    Details
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary One hundred and forty consecutive subarachnoid haemorrhages (SAH) which presented either an intracranial vascular malformation (102 cases: aneurysm 80 cases, AVH 22 cases) or remained of “unknown aetiology” (38 cases) were studied. SAH caused by other factors (neoplasms, thrombo-embolisms, systemic diseases etc.) were excluded. The 38 cases with bleeding of “unknown aetiology” have been studied by complete cerebral angiography, pneumoencephalogram or CT scan, and have been followed for two years. The most important clinical factors in the three groups have been compared by a statistical method to verify the hypothesis that SAH of “unknown aetiology” is caused by vascular micromalformations which are angiographically not evident either because of their small size or because of their “spontaneous” recovery after bleeding due to thrombosis and disappearance of the malformation. From the data collected it may be concluded that SAH of “unknown aetiology” is a benign lesion, typically occurring in middle age, but with no clear characteristics that enable identification of the anatomical substratum from it originates.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02056969
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    Paper (German National Licenses)
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