ISSN:
1013-9826
Source:
Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
Topics:
Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
Notes:
The bone-like self-organized hydroxyapatite/collagen (HAp/Col) nanocomposite spongewas prepared from HAp/Col nanocomposite fibers. We analyzed osteogenic activity of humanosteoblastic MG63 cells in the HAp/Col sponge under pressure/perfusion culture. Collagen (Col)sponge was used as a control. The MG63 cells were attached well and showed good proliferation inthe HAp/Col sponge. The total DNA content in the HAp/Col sponge was approximately 1.8 timesgreater than that in the Col sponge at 21 days. The MG63 cells showed good osteogenic geneexpression in the HAp/Col sponge by reverse transcription-polymerase chain reaction analysis.These result suggested that HAp/Col sponge can be useful for bone tissue engineering scaffoldmaterials
Type of Medium:
Electronic Resource
URL:
http://www.tib-hannover.de/fulltexts/2011/0528/01/56/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.361-363.1079.pdf
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