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  • 1
    Electronic Resource
    Electronic Resource
    Human ecchordosis physaliphora and chick embryonic notochord (1976)
    Springer
    Virchows Archiv 371 (1976), S. 295-303 
    Details
    ISSN: 1432-2307
    Keywords: Ecchordosis physaliphora ; Embryonic chick notochord ; Electron Microscopy ; Chordoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ecchordosis physaliphora, a small gelatinous mass attached to the midline of the clivus, is characterized ultrastructurally by glycogen-laden intracytoplasmic vacuoles, focally distended endoplasmic reticulum and perinuclear cisterns with cytoplasmic invaginations, large clusters of granular endoplasmic reticulum interdigitating with mitochondria, and an abundant extracellular space. These morphologic features are also present in the 9-day embryonal chick notochord and the human chordoma and serve to reaffirm the derivation of the ecchordosis and chordoma from notochordal rests.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00428050
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    In vitro characteristics of a sacrococcygeal chordoma maintained in tissue and organ culture systems (1976)
    Springer
    Acta neuropathologica 35 (1976), S. 13-25 
    Details
    ISSN: 1432-0533
    Keywords: Chordoma ; Tissue and organ culture ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Explants of a human sacral chordoma were successfully maintained on collagen-coated coverslips, gelfoam sponge matrices, and Millipore filter platforms for up to 30 days. Tumor cells cultured on collagen-coated coverslips became increasingly vacuolated whereas those maintained in organ culture were entirely free of vacuoles after 22 days in vitro. A single basic tumor cell, small and polygonal with a large central spherical nucleus and abundant endoplasmic reticulum and Golgi apparatus, was recognized. Vacuoles were formed as the result of the progressive expansion of smooth endoplasmic reticulum. Coalescence of these vacuoles produced the physaliferous cell of light microscopy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688940
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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