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  • 1
    Electronic Resource
    Electronic Resource
    FIGLU EXCRETION TEST IN URINE WITHOUT HISTIDINE LOADING (1962)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 69 (1962), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1962.tb01274.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Immunoglobulin G (IgG) Localization During Acute Autoimmune Demyelination (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 540 (1988), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1988.tb27084.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Oligodendrocyte Proliferation and Enhanced CNS Remyelination after Therapeutic Manipulation of Chronic Relapsing EAE (1988)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 540 (1988), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1988.tb27222.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Control of metalloprotein redox potentials: what does site-directed mutagenesis of hemoproteins tell us? (1997)
    Springer
    JBIC 2 (1997), S. 119-125 
    Details
    ISSN: 1432-1327
    Keywords: Key words Redox potentials ; Hemoproteins ; Electrostatic interactions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract  An overview of factors affecting metalloprotein redox potentials is given, together with an assessment of the role of site-directed mutagenesis of hemoproteins in investigating this topic and a description of several theoretically challenging hemoproteins. The conclusion is reached that a quantitative and experimentally testable description of metalloprotein redox potentials is not yet available.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s007750050115
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Flower power (1992)
    [s.l.] : Nature Publishing Group
    Nature 359 (1992), S. 598-598 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] PHYTOCHROME is a blue-green pigment that acts as a plant photoreceptor protein in the mediation of many light-activated processes including seed germination, leaf formation, circadian rhythms and flowering. Such physiological processes are often sensitive to the quality, quantity or duration of ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/359598a0
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  • 6
    Electronic Resource
    Electronic Resource
    Hippocampal synaptic pathology in patients with temporal lobe epilepsy (1994)
    Springer
    Acta neuropathologica 87 (1994), S. 202-210 
    Details
    ISSN: 1432-0533
    Keywords: Temporal lobe epilepsy ; Hippocampal sclerosis ; Synaptophysin ; Anti-synaptic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Immunostaining of synaptic terminals was studied in the hippocampus of 26 patients who had surgical resections for intractable temporal lobe epilepsy. Two monoclonal antibodies (EP10 and SP12) reactive with distinct synaptic antigens were used on paraffinembedded tissues. The results indicated qualitative reductions on synaptic terminals in CA4 and other regions where cell loss is reported. The inner molecular layer of the dentate gyrus was observed to have increased synaptic immunostaining. Synaptic terminal loss in CA4 and redistribution in the molecular layer were most frequent in cases with hippocampal sclerosis. However, both forms of synaptic pathology were also noted in most cases where the pathological findings were classified as indefinite, and in some cases associated with mass lesions of the temporal lobe. These results support the importance of neuronal loss and synaptic reorganization as possible mechanisms of illness in epilepsy. They also indicate that synaptic immunostaining may be a useful adjunct to routine neuropathological diagnostic techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296191
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  • 7
    Electronic Resource
    Electronic Resource
    Hippocampal synaptic pathology in patients with temporal lobe epilepsy (1994)
    Springer
    Acta neuropathologica 87 (1994), S. 202-210 
    Details
    ISSN: 1432-0533
    Keywords: Key words: Temporal lobe epilepsy – Hippocampal sclerosis – Synaptophysin – Anti-synaptic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Immunostaining of synaptic terminals was studied in the hippocampus of 26 patients who had surgical resections for intractable temporal lobe epilepsy. Two monoclonal antibodies (EP10 and SP12) reactive with distinct synaptic antigens were used on paraffin-embedded tissues. The results indicated qualitative reductions on synaptic terminals in CA4 and other regions where cell loss is reported. The inner molecular layer of the dentate gyrus was observed to have increased synaptic immunostaining. Synaptic terminal loss in CA4 and redistribution in the molecular layer were most frequent in cases with hippocampal sclerosis. However, both forms of synaptic pathology were also noted in most cases where the pathological findings were classified as indefinite, and in some cases associated with mass lesions of the temporal lobe. These results support the importance of neuronal loss and synaptic reorganization as possible mechanisms of illness in epilepsy. They also indicate that synaptic immunostaining may be a useful adjunct to routine neuropathological diagnostic techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00296191
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    Paper (German National Licenses)
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  • 8
    Electronic Resource
    Electronic Resource
    Myelin basic protein does not have a mitogenic effect on adult oligodendrocytes (1995)
    Springer
    Acta neuropathologica 89 (1995), S. 431-437 
    Details
    ISSN: 1432-0533
    Keywords: Key words Oligodendrocytes ; Mitogens ; Myelin basic ; protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Increased numbers of oligodendrocytes and remyelination are frequently observed in multiple sclerosis plaques. It is presumed the increased numbers of oligodendrocytes are due to cell division, but this has not been proven. The mitogens within the lesion which might be responsible for this are unknown. Since oligodendrocyte proliferation occurs in areas in which there is myelin breakdown, we undertook the present study to determine if myelin basic protein (MBP) or its breakdown products could induce oligodendrocyte proliferation. MBP, or MBP digested by the neutral proteinase plasmin, was added in three concentrations to the media of adult bovine oligodendrocytes in culture. Oligodendrocytes were identified by staining for galactocerebroside. Bromodeoxyuridine incorporation was used as a measure of cell division. Oligodendrocytes were found to divide only rarely in regular culture media, in the presence of MBP, plasmin, or MBP digested by plasmin. The results indicate that MBP is not a significant mitogen for the mature oligodendrocyte.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307648
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  • 9
    Electronic Resource
    Electronic Resource
    Myelin basic protein does not have a mitogenic effect on adult oligodendrocytes (1995)
    Springer
    Acta neuropathologica 89 (1995), S. 431-437 
    Details
    ISSN: 1432-0533
    Keywords: Oligodendrocytes ; Mitogens ; Myelin basic protein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Increased numbers of oligodendrocytes and remyelination are frequently observed in multiple sclerosis plaques. It is presumed the increased numbers of oligodendrocytes are due to cell division, but this has not been proven. The mitogens within the lesion which might be responsible for this are unknown. Since oligodendrocyte proliferation occurs in areas in which there is myelin breakdown, we undertook the present study to determine if myelin basic protein (MBP) or its breakdown products could induce oligodendrocyte proliferation. MBP, or MBP digested by the neutral proteinase plasmin, was added in three concentrations to the media of adult bovine oligodendrocytes in culture. Oligodendrocytes were identified by staining for galactocerebroside. Bromodeoxyuridine incorporation was used as a measure of cell division. Oligodendrocytes were found to divide only rarely in regular culture media, in the presence of MBP, plasmin, or MBP digested by plasmin. The results indicate that MBP is not a significant mitogen for the mature oligodendrocyte.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307648
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Isolation and preliminary characterization of ferritin from clover seeds (1995)
    Springer
    BioMetals 8 (1995), S. 47-52 
    Details
    ISSN: 1572-8773
    Keywords: characterization ; ferritin ; isolation ; plant ferritin (clover seed)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Ferritin from clover (Trifolium subterraneum) seeds was isolated and characterized. It was shown to contain polypeptide units of 28–26.5 kDa. The apparent molecular mass of the native protein was 560 kDa. The average iron cores were 4 nm in diameter and contained 1300 iron atoms, with Fe:P = 4:1. Purified clover apoferritin was shown to be functional by means of iron uptake experiments. Plots of initial velocities of iron uptake (at pH 6.7) into clover and horse spleen apoferritins were found to have similar profiles.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00156157
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