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  • 1
    Electronic Resource
    Electronic Resource
    Anorexic Effect of Intraperitoneal Glucose in the Hypothalamic Hyperphagic Cat (1963)
    [s.l.] : Nature Publishing Group
    Nature 199 (1963), S. 1004-1005 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A total of 23 experiments were performed in 2 adult cats weighing 2.8 and 3.4 kg respectively at the beginning of the work. In these two animals bilateral ventromedial hypothalamic lesions were electrolytically produced. Following these lesions both cats became hyperphagic, increasing their weights ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/1991004a0
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  • 2
    Electronic Resource
    Electronic Resource
    Alterations in Feline Behaviour Following Bilateral Amygdalectomy (1957)
    [s.l.] : Nature Publishing Group
    Nature 180 (1957), S. 598-600 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] THIS experiment was designed to study the behavioural effects of bilateral removal of the amygdaloid complex in the cat and to study any further alterations produced by subsequent neo-decortication. This article will deal only with the first part of the study, that is, the effects of bilateral amy ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/180598a0
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  • 3
    Electronic Resource
    Electronic Resource
    Evidence of a ‘Hunger Motivational’ System in the Lateral Hypothalamus of the Rat (1961)
    [s.l.] : Nature Publishing Group
    Nature 191 (1961), S. 672-674 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] MUCH interest has recently been focused on the iVJL higher nervous control of food and water intake, particularly in the hypothalamic 'centres' concerned with the mechanisms of 'feeding' and 'satiety'. Several investigations1-5 have tended to stress the importance of longitudinal hypothalamic fibre ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/191672a0
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  • 4
    Electronic Resource
    Electronic Resource
    INTRODUCTORY REMARKS (1969)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 157 (1969), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1969.tb12905.x
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  • 5
    Electronic Resource
    Electronic Resource
    THE FUNCTION OF THE LIMBIC AND RHINIC FOREBRAIN-LIMBIC MIDBRAIN SYSTEMS AND RETICULAR FORMATION IN THE REGULATION OF FOOD AND WATER INTAKE (1969)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 157 (1969), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1969.tb12922.x
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  • 6
    Electronic Resource
    Electronic Resource
    Retino-hypothalamic Connexions in Cetacea (1964)
    [s.l.] : Nature Publishing Group
    Nature 203 (1964), S. 778-780 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Fig. 1. Ventral aspect of cetacean brains. A, humpback whale (Megaptera nodosa) optic nerve (ON) and optic tract (OT) are indicated. Anterior lobe of pituitary gland (AP) reflected anteriorly from separate posterior pituitary (PP); B, sperm whale (Physeter catodon) depicting optic nerve (ON) and ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/203778b0
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  • 7
    Electronic Resource
    Electronic Resource
    Paired-pulse facilitation and inhibition in the dentate gyrus is dependent on behavioral state (1989)
    Springer
    Experimental brain research 77 (1989), S. 594-604 
    Details
    ISSN: 1432-1106
    Keywords: Paired-pulse inhibition ; Paired-pulse facilitation ; Dentate gyrus ; Behavioral modulation ; Sleep-waking states
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary It is well established that neuronal transmission from the entorhinal cortex through the dentate gyrus via the perforant path is dependent on behavioral state. To further study the modulation of neuronal transmission by behavioral state we employed the paired-pulse technique to study interneuronally-mediated inhibition and shortterm facilitation in the dentate gyrus of freely-moving rat preparations. Precisely timed double pulses of electrical stimulation were delivered to the perforant path in the chronically implanted rat preparation during each of four well-defined behavioral states: slow-wave sleep (SWS), REM sleep (REM), immobile waking (IW) or active waking with voluntary movements (AW). Evoked field potentials were recorded in the dentate gyrus and analyzed to measure the population spike amplitude which represents the total number of dentate granule cells firing in synchronous response to perforant path stimulation. The paired-pulse index (PPI) was used as a measure of the net short-term facilitation or interneuronally-mediated inhibition effective at the time of the paired-pulse test and is computed by dividing the amplitude of the second population spike (p2) by the amplitude of the first population spike (p1). During the course of this study 3754 paired-pulse tests were performed in 9 rat preparations. The three interpulse interval (IPI) values used in these studies were 25, 30 and 35 ms. The results showed that the PPI was greater during AW and REM as compared to SWS and IW. The PPI was significantly greater during AW than during SWS and IW regardless of p1 amplitude or IPI value. The PPI was significantly greater during AW than during REM under most conditions except those corresponding to low p1 amplitude and long IPI. The PPIs measured during REM were significantly greater than those measured during SWS and IW at short IPIs (25 and 30 ms) but not at an IPI of 35 ms. These results indicate that short-term facilitation is the dominant response during AW especially when observed using an IPI of 35 ms. In contrast, interneuronally-mediated inhibition was observed to be dominant during SWS and IW. The net effect during REM was observed to lie between these two extremes using an IPI of 25 ms and tended toward short-term facilitation at longer IPIs of 30 and 35 ms. Septal disinhibition of dentate granule cells is proposed as the mechanism for this effect. The behavioral state modulaion of neuronal transmission through the dentate gyrus is discussed in terms of this hypothesis. We conclude that there are probably at least two mechanisms underlying the behavioral modulation of field potentials in the dentate gyrus: (1) an indirect influence modulating the activity of inhibitory interneurons and (2) a more direct influence modulating the excitability of granule cells themselves.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00249612
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  • 8
    Electronic Resource
    Electronic Resource
    Power spectrum analysis of EEG synchronization following application of serotonin to area postrema (1972)
    Springer
    Annals of biomedical engineering 1 (1972), S. 246-253 
    Details
    ISSN: 1573-9686
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Technology
    Notes: Abstract The role of serotonin and of the area postrema in synchronization of the neocortical electroencephalogram (EEG) was investigated in the present studies by observing the effects of different drugs (serotonin, norepinephrine, acetylcholine, and Xylocaine) applied topically at the site of the area postrema in cats. Using Fast Fourier Spectral analysis and power density spectra techniques it was found that serotonin increased the low frequency components and decreased the high frequency components in the cortical EEG. Application of serotonin to the floor of the fourth ventrical 6 mm rostral to the area postrema never produced EEG synchronizing effects. Xylocaine applied directly to the area postrema, as well as lesions of this region, decreased the low frequency components of the EEG while norepinephrine and acetylcholine produced variable effects. These results indicate that a serotonergic-sensitive mechanism, which induces EEG synchronization, exists in the region of the area postrema.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00000009
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  • 9
    Electronic Resource
    Electronic Resource
    The anatomy of the cervicothoracic arterial system in the bottlenose dolphin (Tursiops truncatus) with a surgical approach suitable for guided angiographyThis research was supported by grant NB 03097, National Institute of Neurological Disease and Blindness, National Institutes of Health, and N.S.F. grant GB 4407 to Communication Research Institute. (1966)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 155 (1966), S. 325-337 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Anatomical dissections on the cervicothoracic arterial system of the bottlenose dolphin (Tursiops truncatus) have been carried out as a necessary stage preceding certain physiological investigations in this animal. It is essential to have access to large blood vessels in these investigations, and the lack of superficial blood vessels suitable for catheterization in this species has required that a surgical approach to deeper vessels be developed. We have described a surgical technique for exposure of the A. carotis externa and V. jugularis externa and have used this method to introduce angio-catheters into both of these vessels. By these means we have been able to carry out hemodynamic, blood chemistry, and angiographic studies with successful recovery of the animals. These investigations, anatomical dissections on normal animals, and studies of vinylite vascular casts have delineated many specialized features of the cervicothoracic vascular systems in the dolphin.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091550306
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