ISSN:
1573-8221
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Summary A study was made of the effect produced by thyroidin on blood cholesterol and on the cholesterol content of various organs of rabbits kept on the usual diet, and developing atherosclerosis induced dietetically. In rabbits kept on a normal diet administration of 0.06 g/kg thyroidin for 45 days did not influence the cholesterol content of the blood, aorta, liver, or brain, but did cause an increase in the adrenal glands. When cholesterol was fed to animals for 45 days, the same doses of thyroidin caused a greater accumulation of cholesterol in the liver, adrenal glands, and brain than was found in animals given cholesterol alone. In the animals treated with thyroidin the increased blood cholesterol was prevented. When thyroidin and cholesterol were given no lipid plaques developed in the aorta, though they did when the rabbits received cholesterol alone. Nevertheless, the amount of cholesterol per unit dry weight of aorta was the same in both groups of animals.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00785665
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