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  • 1
    Electronic Resource
    Electronic Resource
    Licensed Midwife-Attended, Out-of-Hospital Births in Washington State: Are They Safe? (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Birth 21 (1994), S. 0 
    Details
    ISSN: 1523-536X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: : The safety of out-of-hospital births attended by midwives who are licensed according to international standards has not been established in the United States. To address this issue, outcomes of births attended out of hospital by licensed midwives in Washington state were compared with those attended by physicians and certified nurse-midwives in hospital and certified nurse-midwives out of hospital between 1981 and 1990. Outcomes measured included low birthweight, low five-minute Apgar scores, and neonatal and postneonatal mortality. Associations between attendant and outcomes were measured using odds ratios to estimate relative risks. Multivariate analysis using logistic regression controlled for confounding variables. Overall, births attended by licensed midwives out of hospital had a significantly lower risk for low birthweight than those attended in hospital by certified nurse-midwives, but no significant differences were found between licensed midwives and any of the comparison groups on any other outcomes measured. When the analysis was limited to low-risk women, certified nurse-midwives were no more likely to deliver low-birthweight infants than were licensed midwives, but births attended by physicians had a higher risk of low birthweight. The results of this study indicate that in Washington state the practice of licensed nonnurse-midwives, whose training meets standards set by international professional organizations, may be as safe as that of physicians in hospital and certified nurse-midwives in and out of hospital.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1523-536X.1994.tb00513.x
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  • 2
    Electronic Resource
    Electronic Resource
    Forensic science (2003)
    [s.l.] : Nature Publishing Group
    Nature 421 (2003), S. 872-873 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] ...Geneticist Patrick O'Donnell was happy to help police with their enquiries when they rang him in 1990. During a postdoc at San Diego State University, O'Donnell had started to question whether he wanted to remain in academic research. The San Diego Police Department (SDPD) Crime Laboratory was ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nj6925-872a
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    Paper (German National Licenses)
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  • 3
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    TOWARD UNDERSTANDING THE CHANGING WORK ETHIC (1974)
    Berkeley, Calif. : Periodicals Archive Online (PAO)
    California Management Review. 16:3 (1974:Spring) 
    Details
    ISSN: 0008-1256
    Topics: Economics
    URL: http://gateway.proquest.com/openurl?url_ver=Z39.88-2004&res_dat=xri:pao:&rft_dat=xri:pao:article:5018-1974-016-03-000001
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  • 4
    Electronic Resource
    Electronic Resource
    Mitoxantrone, vincristine, and 5-fluorouracil with leucovorin modulation as induction chemotherapy prior to high-dose intensification in metastatic breast cancer (1993)
    Springer
    Breast cancer research and treatment 28 (1993), S. 291-294 
    Details
    ISSN: 1573-7217
    Keywords: breast cancer ; induction chemotherapy ; mitoxantrone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We treated 39 women with newly diagnosed stage IV breast cancer with a new regimen of mitoxantrone 18 mg/m2 on days 1, 29, 57, vincristine 1.4 mg/m2 (maximum 2.0 mg) on days 1, 8, 15, 22, 29, 36, 43, 50, and 5-fluorouracil 375 mg/m2 on days 15–20, 43–47, 71–75 with leucovorin modulation 500 mg/m2 before each 5FU infusion (MVF). This regimen was utilized as an initial cytoreductive or induction program for these patients prior to high-dose intensification with autologous stem cell rescue. Ten patients (25%) obtained a clinical complete response and six patients (15%) obtained a partial response for an overall response rate of 40%. In addition, 10 patients had evaluable disease that was improved or stable (primarily bone and/or bone marrow metastases) after MVF induction. Thus, 26 patients (65%) were eligible for high-dose intensification with autologous stem cell rescue after MVF induction. Toxicity was primarily a mild mucositis and more commonly peripheral neuropathy. MVF therapy is an active treatment program for metastatic breast cancer but the neurotoxicity makes it difficult to recommend for widespread use.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00666591
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  • 5
    Electronic Resource
    Electronic Resource
    New strategies in marrow purging for breast cancer patients receiving high-dose chemotherapy with autologous bone marrow transplantation (1993)
    Springer
    Breast cancer research and treatment 26 (1993), S. S19 
    Details
    ISSN: 1573-7217
    Keywords: amifostine ; autologous bone marrow transplantation (ABMT) ; breast cancer ; 4-hydroperoxycyclophoshamide (4-HC) ; marrow purging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary High-dose chemotherapy and autologous bone marrow transplantation (ABMT) are commonly used to treat selected patients with high-risk breast cancer. A limitation of ABMT is that clonogenic cancer cells could be collected with the bone marrow and produce a relapse of disease when reinfused into patients. Purging the marrowex vivo may eliminate the tumor cells, but it can also delay engraftment. We employed two different purging methods whereby breast cancer cells were depleted without delaying engraftment. The addition of WR-2721 (amifostine) to 4-hydroperoxycyclophosphamide (4-HC) reduced the time to engraftment by 10 days compared with marrow purged with 4-HC alone (26 versus 37 days, respectively). The positive selection of CD34+ hematopoietic progenitors produced engraftment within 21 days. The use of granulocyte colony-stimulating factor (G-CSF) accelerated the engraftment time of CD34+ hematopoietic progenitors to 11 days.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00668356
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    Paper (German National Licenses)
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