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  • 1
    Electronic Resource
    Electronic Resource
    Transient cells of the developing mammalian telencephalon are peptide-immunoreactive neurons (1987)
    [s.l.] : Nature Publishing Group
    Nature 325 (1987), S. 617-620 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] We identified the subplate and marginal zone cells unam-bigously by their birthdate. These cells undergo their final round of cell division and migrate away from the ventricular zone between embryonic day 24 (E24) and E30 (gestation is 65 days in the cat)1. In contrast, cells of the cortical layers ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/325617a0
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mechanism of chlorpromazine binding by Gram-positive and Gram-negative bacteria (1992)
    Springer
    Antonie van Leeuwenhoek 62 (1992), S. 309-314 
    Details
    ISSN: 1572-9699
    Keywords: chlorpromazine ; xanthene dyes ; charge-transfer complexes ; birefringence ; Gram-positive and Gram-negative cell wall stain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Chlorpromazine forms charge-transfer complexes with xanthene dyes in bacteria. These complexes permit the differentiation of Gram-positive and Gram-negative bacteria in both light and polarization microscopy. The birefringence induced by the charge-transfer complex might explain the molecular basis of bacterial staining. The charge-transfer complexes formed between chorpromazine and xanthene dyes accumulate in the bacterial cell, mainly inside the bacterial cell wall. The complexes give the cells a color, which depends on the chemical composition of the staining structure, and in particular the polysaccharides of the cell wall in bacteria. Metachromatic granules were seen inside Gram-positive bacteria after chlorpromazine and rose bengal staining. Although the nature of these granules remains unclear, this type of binding may have a role in the inhibition of biochemical processes in the bacterial cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572599
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Effects of some tricyclic psychopharmacons and structurally related compounds on motility ofProteus vulgaris (1992)
    Springer
    Antonie van Leeuwenhoek 62 (1992), S. 315-320 
    Details
    ISSN: 1572-9699
    Keywords: phenothiazines ; inhibition ; bacterial motility ; proton pump antagonism ; Proteus vulgaris
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A simple test for the evaluation of drugs interfering with bacterial motility was established withProteus vulgaris. With this model, promethazine, 7-hydroxy-chlorpromazine, imipramine, 7,8-dioxochlorpromazine and acridine orange were shown to exert significant motility and swarming inhibitory action onProteus vulgaris strains at subinhibitory concentrations. Quinidine enhanced the antimotility effect of promethazine. The antimotility effect of promethazine was synergized by proton pump inhibitors omeprazole and abscissic acid, but antagonized by extracellular potassium and sodium ions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00572600
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    Paper (German National Licenses)
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