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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 48 (1981), S. 331-337 
    ISSN: 1432-1246
    Keywords: Biochemical changes ; Chronic noise exposure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Biochemical parameters in 75 normal healthy male subjects exposed to intense noise of 88–107 dB(A) (6–8 h/day) for 10 to 15 years during their work situation have been monitored and compared with 35 normal unexposed subjects. Levels of free cholesterol (P〈0.001), γ-globulin (P〈0.01) and cortisol (P〈0.01) were found to be significantly higher in the exposed subjects. Significant changes in free cholesterol also altered the ratio of free to esterified cholesterol significantly (P〈0.001). The value of the A/G ratio was also lower in the exposed group. Uric acid did not show any change. The study shows that in the exposed group the esterification process of cholesterol was modified. There was an effect on pituitary-adrenal axis as well as host-defence mechanism.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract Studies were carried out to ascertain the role of sympatho-parasympathetic responses in the process of adaptation to altitude. The assessment of status of autonomic balance was carried out in a group of 20 young male subjects by recording their resting heart rate, blood pressure, oral temperature, mean skin temperature, extremity temperatures, pupillary diameter, cold pressor response, oxygen consumption, cardioacceleration during orthostasis and urinary excretion of catecholamines; in a thermoneutral laboratory. The same parameters were repeated on day 3 and at weekly intervals for a period of 3 weeks, after exposing them to 3,500 m; and also after return to sea level. At altitude, similar studies were carried out in a group of 10 acclimatized lowlanders, 10 high altitude natives and 6 patients who had recently recovered from high altitude pulmonary oedema. In another phase, similar studies were done in two groups of subjects, one representing 15 subjects who had stayed at altitude (3,500–4,000 m) without any ill effects and the other comprising of 10 subjects who had either suffered from high altitude pulmonary oedema (HAPO) or acute mountain sickness (AMS). The results revealed sympathetic overactivity on acute induction to altitude which showed gradual recovery on prolonged stay, the high altitude natives had preponderance to parasympathetic system. Sympathetic preponderance may not be an essential etiological factor for the causation of maladaptation syndromes.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    International journal of biometeorology 25 (1981), S. 191-198 
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract Studies were conducted on 15 healthy young soldiers to evaluate the effect of a cold acclimatization schedule on the thermoregulatory and metabolic activity on exposure to acute cold stress. These men were exposed to cold (10
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International journal of biometeorology 23 (1979), S. 263-270 
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract The peripheral vascular responses during local cold stress, (heat output from the hands and cold induced vasodilatation-CIVD response) were studied on 4 groups (10 each) of Indian population, viz., South-Indians, North-Indians, Gurkhas and High Altitude Natives (HAN) of 3,500m. The parameters were recorded at Delhi, and at 3,500 m in thermoneutral laboratory (25–28°C). The sea level readings of HAN were taken after 3 weeks of their stay at Delhi; and that of lowlanders at 3,500 m were taken after 3 weeks of their sojourn. The results show that the heat output and CIVD were highest in HAN, and lowest in the South-Indians. The responses of the other two groups were similar in nature and were better than that of South-Indians. Based on an earlier study which has shown that individuals with higher heat output and CIVD are better protected against the occurrence of cold injuries, it can be suggested that HAN are most resistant and the South-Indians are highly susceptible to the occurrence of cold injuries.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International journal of biometeorology 25 (1981), S. 47-52 
    ISSN: 1432-1254
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geography , Physics
    Notes: Abstract Body fluid compartments were studied in a group of high altitude natives after a stay of two months at sea level and during 12 days at an altitude of 3,500 m. Measurements of total body water and extracellular water were made on day 3 and 12 of reinduction to altitude, while plasma volume was measured on day 12 only. The intracellular water, blood volume and red cell mass were computed from the above parameters. Total body water and intracellular water decreased by 3.3% (P〈0.001) and 5.0% (P〈0.001) respectively by the 3rd day at altitude and did not change thereafter. Extracellular water increased progressively at altitude, but the increase was not significant. Blood volume and red cell mass increased significantly while plasma volume decreased at altitude. These data were compared with that of low landers. This study suggested body hypohydration on high altitude induction in low landers as well as in high altitude natives on reinduction.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 50 (1982), S. 169-174 
    ISSN: 1432-1246
    Keywords: Noise level ; Blood pressure ; Heart rate ; Chronic noise exposure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Physiological parameters have been compared in 75 normal healthy individuals exposed to occupational noise of 88–107 dB (A) (6–8h/day) for 10–15 years and in 36 normal non-exposed subjects. Blood pressure, both systolic (P〈0.01) and diastolic (P〈0.001), and heart rate (P〈0.05) were found to be significantly higher in the exposed subjects. Irregularity in cardiac rhythm, both in amplitude and duration, was found in 18% of the exposed subjects as against 6% in the non-exposed group. Variation in the heart rate during acute noise exposure of 90 dB (A) has been shown to be related with the preponderance of tonicity of sympathetics and parasympathetics. Measurement of hand blood flow during the same exposure showed a lesser degree of vasoconstriction and a slower recovery rate in the exposed group. Altered observations in the exposed group could be attributed to changes in the mechanical property of blood vessels.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 51 (1983), S. 137-144 
    ISSN: 1439-6327
    Keywords: Chemoreceptor sensitivity ; High altitude ; Maladaptation syndromes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Studies were carried out to find out the role of chemoreceptor sensitivity in the causation of maladaptation syndromes on acute exposure to altitude. The experiments were done in two phases. In phase I, the responses in chemoreceptor sensitivity were studied in altitude acclimatized subjects and compared with those who suffered from either High Altitude Pulmonary Oedema (HAPO) or Acute Mountain Sickness (AMS). In Phase II, a similar comparison was done in two groups of subjects, one representing normal sojourners at 3,500 m and the other being subjects who had just recovered from HAPO. The first phase was done at Delhi; and the second at an altitude of 3,500 m. Parameters of assessment were hypoxic sensitivity, carbon dioxide sensitivity, ventilation ( $$\dot V$$ E), respiratory frequency (Rf), forced vital capacity (FVC), forced expiratory volume at the first second (FEV1), heart rate (HR), blood pressure (BP), and oral temperature (Tor). The results showed significantly lower sensitivity to both hypoxia and carbon dioxide in maladapted subjects, as compared to those who were well acclimatized in both the categories suggesting thereby that reduced chemoreceptor sensitivity might be an initiating factor in the causation of maladaptation syndromes at altitude.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    European journal of applied physiology 47 (1981), S. 65-72 
    ISSN: 1439-6327
    Keywords: High altitude natives ; Body density ; Body water ; Anthropometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Body density was experimentally determined at a field location at 3,920 m on 32 medically fit and active high altitude native males using a water displacement technique. Stature, body weight and the bony widths at the elbow, wrist, knee, and ankles; and thickness of skin folds at eight sites were measured. Based on body density and bony widths, body fat, total body water (TBW), mineral mass and total cell solids (TCS) were calculated. Similar measurements were made on another group of 16 high altitude natives after one months stay in Dehli (200 m). TBW of 11 of these subjects was experimentally determined by the oral administration of 200 ΜCi of tritiated water. This group of subjects was physically less active in Delhi. At high altitude the natives consumed a balanced diet which provided 20.21 MJ, but in the plains the diet provided only 15.69 MJ though it was nutritionally balanced. In spite of the reduced calorie intake this group showed greater fat content in Delhi than the group located at high altitude. These men were also hyperhydrated. Hyperhydration of the lean body could be an adaptive response of the high altitude natives to the new environment. Due to the disturbed state of hydration of the lean body of these men in the plains, use of Siri's formula for the computation of total body fat is questioned.
    Type of Medium: Electronic Resource
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