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  • 1
    ISSN: 1128-045X
    Keywords: Key words Coloanal anastomosis ; Defunctioning stoma ; Complications ; Disease-free survival
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The role of a temporary defunctioning stoma in patients undergoing coloanal anastomosis remains controversial. Previous experimental studies have shown that the defunctioned colon is more resistant to neoplasia. The aim of this study was to investigate whether a defunctioning stoma was able to decrease complication rates and, also, to evaluate whether it had any impact on recurrence and survival rates in patients who underwent coloanal anastomosis. The records of 173 patients, 54 with benign rectal disease and 119 patients with cancer, operated on between 1980 and 1996, were retrospectively reviewed. Eighty-nine patients had a defunctioning stoma, 34 in the benign rectal disease and 55 in the cancer group. Mean age was 57.2 years (range 17–88). There were 126 men and 47 women. Follow-up was 57.2 month (range 17–88). There were 126 men and 47 women. Follow-up was done by clinical examination, telephone or mailed questionnaire. Mean time of follow-up was 3.8 years (range 0–13 years). There was no operative mortality. Non-stoma patients tended to have more early complications (pelvic sepsis and obstruction) and more probability of having a permanent stoma than the stoma group, but no significant differences could be found between the two groups (P 〉 0.05). The probability of being free of stricture was greater in the non-stoma group (stoma 62.6%; non-stoma 78.5%; P 〈 0.05). Probability of disease-free survival, at 5 years, for rectal cancer patients, was 73.7% for the stoma group and 53.6% for non-stoma group (P = 0.02). After coloanal anastomosis, defunctioning stomas may decrease postoperative complications, increase the likelihood of anastomosis structure and allow a greater disease-free survival.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les différents rapports concernant les résultats à long terme de la chirurgie d'exérèse de la maladie de Crohn limitée au colon sont contradictoires. C'est ainsi que le taux des récidives au niveau de l'intestin grêle varie de 3 à 46% selon les statistiques. Les variations constatées sont inhérentes à de multiples facteurs: différence dans le choix des malades, des critères pathologiques, ainsi que la définition des récidives, durée, précision, étude complète des suites évolutives post-opératoires. Un fait est certain: les taux de récidive varient en fonction de l'étendue de l'exérèse. En se basant sur l'étude rétrospective de 35 malades, les auteurs aboutissent aux conclusions suivantes: (1) quand la totalité du colon malade est réséquée la récidive est rare; (2) il est seulement nécessaire de pratiquer l'exérèse des segments coliques intéressés; (3) les tentatives de conservation du rectum, lorsqu'il est atteint, en ayant recours à une colostomie ou à une opération de Hartmann se soldent par des échecs; (4) la reconstitution de la continuité digestive par une anastomose d'emblée est possible si le rectum est intact.
    Abstract: Resumen Los informes sobre resultados a largo plazo de la cirugía extirpativa para la enfermedad de Crohn limitada al intestino grueso, la cual se reconoce como una entidad diferente de otras formas de colitis, han revelado cifras aparentemente contradictorias, con tasas de recurrencia que oscilan entre el 3% y el 46%. Variaciones en cuanto a la selección de los pacientes, diferentes criterios histopatológicos y diferentes criterios para definir las recurrencias, así como la extensión y el rigor del seguimiento postoperatorio, bien pueden explicar las diferencias encontradas en la literatura. Ciertamente la magnitud del procedimiento operatorio puede influir sobre las tasas de recurrencia. Se realizó una revisión retrospectiva con el propósito de determinar si la resección segmentaria del colon puede ser justificada en pacientes con enfermedad de Crohn clínicamente confinada al colon. Se analizaron 35 pacientes seguidos por 6 meses a 12 años (4.6 años en promedio), después de haber excluído a aquellos con afección del intestino delgado (enfermedad ileo-cólica), y a los que no reunían los criterios de Morson y de Korelitz para enfermedad de Crohn del colon. La indicatión más frecuente para operación fue la intratabilidad, tanto abdominal como perineal: la enfermedad se encontró ⌞mitada al recto-sigmoideo en 11 casos, a la totalidad del colon y recto en 11 y a segmentos del colon diferentes de la región recto-sigmoidea en 13. El enfoque selectivo del manejo operatorio de la colitis de Crohn, basado en la resectión de la región específica del colon que se encuentre afectada, parece ser razonable. Se pueden hacer cuatro sugerencias relativas al manejo quirÚrgico de esta entidad: 1. Con la extirpación de la totalidad del colon que se encuentre clínicamente afectado, la tasa de recurrencia es baja; 2. Solo es necesario extirpar los segmentos afectados; 3. Los esfuerzos por salvar el recto cuando obviamente hay enfermedad presente, mediante una fístula mucosa o un procedimiento de Hartmann, muy rara vez resultan exitosos; 4. En presencia de un recto realmente libre de enfermedad, la resección segmentaria del colon afectado con anastomosis primaria es un procedimiento seguro y potencialmente Útil. Nuestros resultados generales con este enfoque parecen ubicarse en un lugar intermedio, con 7 de 35 patientes (20%) que requirieron re-operación para recurrencia o persistencia de la enfermedad.
    Notes: Abstract Reports of the long-term results of excisional surgery for Crohn's disease restricted to the large intestine have revealed apparently conflicting data. Recurrent enteritis after colectomy and ileotomy varies from 3% to 46%. Variations in patient selection, differences in pathologic criteria and criteria for defining recurrences, and length, completeness, and accuracy of the follow-up may well explain such differences in the literature. Certainly, the extent of the operative procedure could influence recurrence rates. A retrospective review was undertaken to determine whether segmental colon resection was ever justified in patients with Crohn's disease clinically confined to the colon.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Diseases of the colon & rectum 40 (1997), S. 661-668 
    ISSN: 1530-0358
    Keywords: Anorectal melanoma ; Melanoma ; Surgical treatment ; Abdominoperineal resection ; Wide local excision ; Recurrence ; Anus ; Rectum ; Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract PURPOSE: This study was designed to describe recurrence and survival rates after operative treatment for anorectal melanoma and to identify predictive factors for recurrence. METHODS: Records of 50 patients with anorectal melanoma from 1939 to 1993 were reviewed. RESULTS: Overall five-year survival and disease-free survival were 22 and 16 percent, respectively. At the time of diagnosis, 26 percent of patients had metastatic disease, and all died within 12 (mean, 6.3) months. Five-year survival and recurrence rates were identical after either abdominoperineal resection (APR) or wide local excision, both with curative intent. Gender, size of tumor, presence of melanin, positive perirectal lymph nodes, or treatment were not predictive of recurrence. Anorectal melanoma was found incidentally after hemorrhoidectomy or polypectomy in five patients. Three other patients underwent an excisional biopsy of a lesion measuring less than 2 cm. Of these eight patients, five underwent APR and three underwent wide local excision with no microscopic residual tumor at pathology. All developed regional or systemic recurrence at a mean of 21 (range, 4–88) months, and all died of their disease at a mean of 29 (range, 5–98) months. CONCLUSION: Prognosis for anorectal melanoma is poor, irrespective of surgical treatment performed. No predictive factors for recurrence were identified in this series. Wide local excision with a negative margin of a least 1 cm is suggested as the treatment of choice. APR should be reserved for tumor not amenable to local excision or for palliative treatment of large obstructive lesion until effective adjuvant therapies are available.
    Type of Medium: Electronic Resource
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