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Immunohistochemistry of proliferating cell nuclear antigen (PCNA), laminin, and electron microscopy by tannic acid fixation in surface epithelial-stromal ovarian tumors (1994)

Hiura, Masamichi ; Nogawa, Takayoshi ; Moriwaki, Shosuke

Springer

Medical molecular morphology 27 (1994), S. 268-270

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ISSN: 1860-1499

Keywords: PCNA ; Laminin ; Tannic acid ; Immunohistochemistry ; Electron microscopy

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract The distribution of proliferating cell nuclear antigen (PCNA), laminin, and basement membrane in surface epithelial-stromal ovarian tumors was studied using immunohistochemical and cytochemical techniques. PCNA is a useful means of differentiating between borderline and malignant tumors. The distribution of laminin-positive materials in malignant tumors showed that laminin synthesis in these tumors is quite different from that which occurs in benign or borderline tumors. This corresponded with electron microscopic findings by tannic acid fixation showing pleomorphism of cell organelles and discontinuity of the basement membrane in malignant tumors.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF02349672

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A quantitative analysis of mitochondria during fetal mouse oogenesis (1988)

Nogawa, Takayoshi ; Sung, Weng Kong ; Jagiello, Georgiana M. ; [et al.]

New York, NY : Wiley-Blackwell

Journal of Morphology 195 (1988), S. 225-234

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ISSN: 0362-2525

Keywords: Life and Medical Sciences ; Cell & Developmental Biology

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Biology , Medicine

Notes: A quantitative analysis of mitochondrial populations during the meiotic prophase of mouse oogenesis was carried out. The mean absolute area occupied by mitochondria and the mean number of mitochondria per cell increases in a linear fashion from pachytene through dictyate. The mean area occupied by mitochondria increases at pachytene and thereafter. Both small and large aggregations of mitochondria are seen, particularly during the later stages of prophase. Vacuolated mitochondria are present from preleptotene through pachytene. Mitochondria show major dynamic changes throughout fetal mouse oogenesis, which may suggest significant functional activities yet to be elucidated.

Additional Material: 5 Ill.